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ChemicalBook >> CAS DataBase List >> 3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide

3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide

3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide price.
  • $37 - $1173
  • Product name: 3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide
  • CAS: 461000-66-8
  • MF: C22H24N2O5S
  • MW: 428.5
  • EINECS:
  • MDL Number:MFCD03115431
  • Synonyms:3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide;Eact;3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide;Benzamide, 3,4,5-trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-;Eact >=98% (HPLC);inhibit,Eact,Inhibitor,Chloride Channel,Cl? Channels
Price22 Properties Safety Information Description
22 prices
Selected condition：
Brand
  • aablocks
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 2.5mg
  • 1mg
  • 50
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • Manufactureraablocks
  • Product numberAA00DLTC
  • Product description3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide 100%
  • Packaging5mg
  • Price$167
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA00DLTC
  • Product description3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide 100%
  • Packaging25mg
  • Price$442
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0246CK
  • Product description3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
  • Packaging10mg
  • Price$334
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number0246CK
  • Product description3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
  • Packaging1mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5746
  • Product descriptionEact
  • Packaging50mg
  • Price$1173
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29791
  • Product descriptionEact
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29791
  • Product descriptionEact
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29791
  • Product descriptionEact
  • Packaging10mg
  • Price$213
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29791
  • Product descriptionEact
  • Packaging25mg
  • Price$442
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0027763
  • Product descriptionEact 98.28%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0027763
  • Product descriptionEact 98.28%
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0027763
  • Product descriptionEact 98.28%
  • Packaging25mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0027763
  • Product descriptionEact 98.28%
  • Packaging50mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0027763
  • Product descriptionEact 98.28%
  • Packaging100mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number176738
  • Product description3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide
  • Packaging100mg
  • Price$990
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1157
  • Product descriptionEact ≥98% (HPLC)
  • Packaging5mg
  • Price$120
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00DLTC 3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide 100% 5mg $167 2021-12-16 Buy
aablocks AA00DLTC 3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)-benzamide 100% 25mg $442 2021-12-16 Buy
AK Scientific 0246CK 3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide 10mg $334 2021-12-16 Buy
AK Scientific 0246CK 3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide 1mg $139 2021-12-16 Buy
ApexBio Technology B5746 Eact 50mg $1173 2021-12-16 Buy
Cayman Chemical 29791 Eact 1mg $37 2024-03-01 Buy
Cayman Chemical 29791 Eact 5mg $116 2024-03-01 Buy
Cayman Chemical 29791 Eact 10mg $213 2024-03-01 Buy
Cayman Chemical 29791 Eact 25mg $442 2024-03-01 Buy
ChemScene CS-0027763 Eact 98.28% 5mg $90 2021-12-16 Buy
ChemScene CS-0027763 Eact 98.28% 10mg $160 2021-12-16 Buy
ChemScene CS-0027763 Eact 98.28% 25mg $330 2021-12-16 Buy
ChemScene CS-0027763 Eact 98.28% 50mg $550 2021-12-16 Buy
ChemScene CS-0027763 Eact 98.28% 100mg $900 2021-12-16 Buy
Matrix Scientific 176738 3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-1,3-thiazol-2-yl)benzamide 100mg $990 2021-12-16 Buy
Sigma-Aldrich SML1157 Eact ≥98% (HPLC) 5mg $120 2024-03-01 Buy
Next Last

Properties

Boiling point :595.9±60.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :2.27±0.10(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Eact is an activator of the calcium-activated chloride channel anoctamin 1 (ANO1). It increases chloride currents in FRT cells expressing human ANO1 (EC50 = 3 μM). It is selective for ANO1 over cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels and epithelial sodium channels (ENaCs) in FRT cells at 10 μM. Eact (20 μM) increases the rate of submucosal gland fluid secretion in human bronchi isolated from patients with cystic fibrosis and healthy individuals. It increases production of mitochondrial reactive oxygen species (ROS), reduces the mitochondrial membrane potential, and induces apoptosis in rat lung microvascular endothelial cells (RLMVECs), as well as reduces total cell counts in pulmonary artery endothelial cell populations isolated from patients with idiopathic pulmonary arterial hypertension (IPAH). Eact also activates transient receptor potential vanilloid 1 (TRPV1) in HEK293T cells expressing the mouse receptor (EC50 = 11.6 μM) and induces scratching and licking behaviors in wild-type, but not Trpv1-/-, mice.

Suppliers and manufacturers

TargetMol Chemicals Inc.
Eact
$31.00 /1mg
Eact CAS:461000-66-8
Career Henan Chemica Co
Aladdin Scientific Chembest Research Laboratories Limited Sigma-Aldrich EMMX Biotechnology LLC Shanghai EFE Biological Technology Co., Ltd. MQ (shanghai) Pharmaceuticals Co., Ltd. BOC Sciences ChemeGen(Shanghai) Biotechnology Co.,Ltd.