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ChemicalBook >> CAS DataBase List >> (3β,24S)-Cholest-5-ene-3,24-diol

(3β,24S)-Cholest-5-ene-3,24-diol

(3β,24S)-Cholest-5-ene-3,24-diol price.
  • $68 - $1131.9
  • Product name: (3β,24S)-Cholest-5-ene-3,24-diol
  • CAS: 474-73-7
  • MF: C27H46O2
  • MW: 402.65
  • EINECS:
  • MDL Number:MFCD03695560
  • Synonyms:(3S,8S,9S,10R,13R,14S,17R)-17-[(1R,4S)-4-hydroxy-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;24-hydroxycholesterol ;cholest-5-ene-3-beta,24-diol;(3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-hydroxy-6-methyl-heptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol;cholest-5-ene-3β,24(S)-diol;CHOLEST-5-ENE-3Β,24(S)-DIOL;24(S)-HYDROXYCHOLESTEROL;(24S)-24-hydroxycholesterol;24(S)-HYDROXYCHOLESTEROL
12 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0001850
  • Product description(3BETA,24S)-CHOLEST-5-ENE-3,24-DIOL 95.00%
  • Packaging10MG
  • Price$1131.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3997
  • Product description24(S)-hydroxyCholesterol
  • Packaging1mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3997
  • Product description24(S)-hydroxyCholesterol
  • Packaging5mg
  • Price$361
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3997
  • Product description24(S)-hydroxyCholesterol
  • Packaging10mg
  • Price$686
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009931
  • Product description24(S)-hydroxy Cholesterol ≥95%
  • Packaging1mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009931
  • Product description24(S)-hydroxy Cholesterol ≥95%
  • Packaging5mg
  • Price$319
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009931
  • Product description24(S)-hydroxy Cholesterol ≥95%
  • Packaging10mg
  • Price$601
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0012985
  • Product description24(S)-Hydroxycholesterol
  • Packaging10mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number731
  • Product description24(S)-Hydroxycholesterol 98%
  • Packaging1mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1648
  • Product description24(S)-Hydroxycholesterol ≥98% (HPLC)
  • Packaging5MG
  • Price$504
  • Updated2023-06-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1648
  • Product description24(S)-Hydroxycholesterol ≥98% (HPLC)
  • Packaging1MG
  • Price$124
  • Updated2023-06-20
  • Buy
  • ManufacturerTRC
  • Product numberC431750
  • Product description(3β,24S)-Cholest-5-ene-3,24-diol
  • Packaging5mg
  • Price$470
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation SHG0001850 (3BETA,24S)-CHOLEST-5-ENE-3,24-DIOL 95.00% 10MG $1131.9 2021-12-16 Buy
ApexBio Technology C3997 24(S)-hydroxyCholesterol 1mg $77 2021-12-16 Buy
ApexBio Technology C3997 24(S)-hydroxyCholesterol 5mg $361 2021-12-16 Buy
ApexBio Technology C3997 24(S)-hydroxyCholesterol 10mg $686 2021-12-16 Buy
Cayman Chemical 10009931 24(S)-hydroxy Cholesterol ≥95% 1mg $68 2024-03-01 Buy
Cayman Chemical 10009931 24(S)-hydroxy Cholesterol ≥95% 5mg $319 2024-03-01 Buy
Cayman Chemical 10009931 24(S)-hydroxy Cholesterol ≥95% 10mg $601 2024-03-01 Buy
ChemScene CS-0012985 24(S)-Hydroxycholesterol 10mg $1000 2021-12-16 Buy
Medical Isotopes, Inc. 731 24(S)-Hydroxycholesterol 98% 1mg $290 2021-12-16 Buy
Sigma-Aldrich SML1648 24(S)-Hydroxycholesterol ≥98% (HPLC) 5MG $504 2023-06-20 Buy
Sigma-Aldrich SML1648 24(S)-Hydroxycholesterol ≥98% (HPLC) 1MG $124 2023-06-20 Buy
TRC C431750 (3β,24S)-Cholest-5-ene-3,24-diol 5mg $470 2021-12-16 Buy

Properties

Melting point :174-176 °C
Boiling point :513.1±23.0 °C(Predicted)
Density :1.03±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 10 mg/ml) or in Ethanol (up to 10 mg/ml).
form :powder
pka :15.03±0.70(Predicted)
color :white to beige
optical activity :[α]/D -45 to -52°, c = 1 in chloroform-d
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that has important roles in cholesterol homeostasis. It is generated by the action of CYP46 on cholesterol in the brain and diffuses across the blood-brain barrier to the systemic circulation where it can modulate cell signaling, be used for further sterol biosynthesis, or be metabolized in the liver. 24(S)-hydroxy cholesterol potently activates LXRα and LXRβ nuclear receptors (EC50 = 4 and 3 μM, respectively), causing upregulation of cholesterol-lowering genes. In the brain, this oxysterol controls cholesterol processing to facilitate neurological repair during Alzheimer’s disease and other neuropathological conditions.

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