2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one
![2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one price.](/CAS/GIF/521937-07-5.gif)
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- $49 - $1140
- Product name: 2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one
- CAS: 521937-07-5
- MF: C12H11NO3
- MW: 217.22
- EINECS:604-604-1
- MDL Number:MFCD03828155
- Synonyms:PKD Inhibitor, CID755673 ;2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one;CID 755673;3-Hydroxy-5,6,7,8-tetrahydro-10-oxa-8-aza-benzo[a]azulen-9-one;CID 755673 2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one;7-Hydroxy-2,3,4,5-tetrahydro-1H-benzofuro[2,3-c]azepin-1-one;7-hydroxy-2,3,4,5-tetrahydro-[1]benzofuro[2,3-c]azepin-1-one;PKD Inhibitor, CID755673 - CAS 521937-07-5 - Calbiochem
22 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10
- 1mg
- 10mM(in 1mL DMSO)
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product numberY1401
- Product description7-hydroxy-2,3,4,5-tetrahydro-1H-benzofuro[2,3-c]azepin-1-one
- Packaging5mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA539848
- Product descriptionCID-755673 98+%
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA539848
- Product descriptionCID-755673 98+%
- Packaging10mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA539848
- Product descriptionCID-755673 98+%
- Packaging50mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0001040
- Product descriptionCID 755673 95.00%
- Packaging10MG
- Price$289.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8678
- Product descriptionCID755673
- Packaging10mM(in 1mL DMSO)
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1627
- Product descriptionCID755673 98%
- Packaging10mg
- Price$137.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1627
- Product descriptionCID755673 98%
- Packaging50mg
- Price$467.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15924
- Product descriptionCID755673 ≥98%
- Packaging1mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15924
- Product descriptionCID755673 ≥98%
- Packaging5mg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15924
- Product descriptionCID755673 ≥98%
- Packaging10mg
- Price$190
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15924
- Product descriptionCID755673 ≥98%
- Packaging25mg
- Price$416
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31001640
- Product descriptionCID755673 98+%
- Packaging50mg
- Price$386
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7385
- Product descriptionCID-755673 >98%
- Packaging100mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7385
- Product descriptionCID-755673 >98%
- Packaging250mg
- Price$800
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number59062
- Product description3-Hydroxy-5,6,7,8-tetrahydro-10-oxa-8-aza-benzo[a]azulen-9-one
- Packaging50mg
- Price$1140
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | Y1401 | 7-hydroxy-2,3,4,5-tetrahydro-1H-benzofuro[2,3-c]azepin-1-one | 5mg | $232 | 2021-12-16 | Buy |
| Ambeed | A539848 | CID-755673 98+% | 5mg | $65 | 2021-12-16 | Buy |
| Ambeed | A539848 | CID-755673 98+% | 10mg | $85 | 2021-12-16 | Buy |
| Ambeed | A539848 | CID-755673 98+% | 50mg | $144 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0001040 | CID 755673 95.00% | 10MG | $289.8 | 2021-12-16 | Buy |
| ApexBio Technology | A8678 | CID755673 | 10mM(in 1mL DMSO) | $50 | 2021-12-16 | Buy |
| Axon Medchem | Axon1627 | CID755673 98% | 10mg | $137.5 | 2021-12-16 | Buy |
| Axon Medchem | Axon1627 | CID755673 98% | 50mg | $467.5 | 2021-12-16 | Buy |
| Cayman Chemical | 15924 | CID755673 ≥98% | 1mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 15924 | CID755673 ≥98% | 5mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 15924 | CID755673 ≥98% | 10mg | $190 | 2024-03-01 | Buy |
| Cayman Chemical | 15924 | CID755673 ≥98% | 25mg | $416 | 2024-03-01 | Buy |
| Crysdot | CD31001640 | CID755673 98+% | 50mg | $386 | 2021-12-16 | Buy |
| DC Chemicals | DC7385 | CID-755673 >98% | 100mg | $420 | 2021-12-16 | Buy |
| DC Chemicals | DC7385 | CID-755673 >98% | 250mg | $800 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 59062 | 3-Hydroxy-5,6,7,8-tetrahydro-10-oxa-8-aza-benzo[a]azulen-9-one | 50mg | $1140 | 2021-12-16 | Buy |
Properties
Melting point :244-247 °C(Solv: isopropanol (67-63-0); isopropanol (67-63-0))
Boiling point :531.8±38.0 °C(Predicted)
Density :1.341±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
pka :9.00±0.20(Predicted)
form :powder
color :white to tan
Boiling point :531.8±38.0 °C(Predicted)
Density :1.341±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
pka :9.00±0.20(Predicted)
form :powder
color :white to tan
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CID755673 is a small molecule inhibitor of PKD (IC50s = 182, 280, 227 nM for PKD1, 2, and 3, respectively) that exhibits higher selectivity for PKD over Akt, polo-like kinase 1, CDK activating kinase, CAMKII and three different PKC isoforms (IC50s range from 15 to > 50 μM). At 25 μM, CID755673 has been shown to inhibit prostate cancer cell proliferation, cell migration, and invasion.Related product price
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