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ChemicalBook >> CAS DataBase List >> 7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID

7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID

7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID price.
  • $153 - $995
  • Product name: 7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID
  • CAS: 528583-91-7
  • MF: C22H32O5
  • MW: 376.49
  • EINECS:
  • MDL Number:MFCD11976905
  • Synonyms:17(R)-RESOLVIN D1;17(R)-RVD1;7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID;4,9,11,13,15,19-Docosahexaenoic acid, 7,8,17-trihydroxy-, (4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-;OIWTWACQMDFHJG-BJEBZIPWSA-N
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • Cayman Chemical
Package
  • 10μg
  • 25μg
  • 50μg
  • 100μg
  • ManufacturerCayman Chemical
  • Product number13060
  • Product description17(R)-Resolvin D1 ≥95%
  • Packaging10μg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13060
  • Product description17(R)-Resolvin D1 ≥95%
  • Packaging25μg
  • Price$345
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13060
  • Product description17(R)-Resolvin D1 ≥95%
  • Packaging50μg
  • Price$651
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13060
  • Product description17(R)-Resolvin D1 ≥95%
  • Packaging100μg
  • Price$995
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 13060 17(R)-Resolvin D1 ≥95% 10μg $153 2024-03-01 Buy
Cayman Chemical 13060 17(R)-Resolvin D1 ≥95% 25μg $345 2024-03-01 Buy
Cayman Chemical 13060 17(R)-Resolvin D1 ≥95% 50μg $651 2024-03-01 Buy
Cayman Chemical 13060 17(R)-Resolvin D1 ≥95% 100μg $995 2024-03-01 Buy

Properties

Boiling point :609.2±55.0 °C(Predicted)
Density :1.101±0.06 g/cm3(Predicted)
storage temp. :Store at -80°C
solubility :DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml
pka :4.58±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; ) and docosahexaenoic acid (DHA; ). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1; ) is produced physiologically from the sequential oxygenation of DHA by 15- and 5-lipoxygenase. 17(R)-RvD1 is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte (PMN) transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM). 17(R)-RvD1 exhibits a dose-dependent reduction in leukocyte infiltration in a mouse model of peritonitis with maximal inhibition of ~35% at a 100 ng dose. In contrast to RvD1, the aspirin-triggered form resists rapid inactivation by eicosanoid oxidoreductases. Analytical and biological comparisons of synthetic 17(R)-RvD1 with endogenously derived 17(R)-RvD1 have confirmed its identity as matching the natural product.

Suppliers and manufacturers

Aladdin Scientific Shanghai Aladdin Bio-Chem Technology Co.,LTD Shanghai Hongye Biotechnology Co. Ltd ChemeGen(Shanghai) Biotechnology Co.,Ltd. TargetMol Chemicals Inc. Shanghai Yifei Biotechnology Co. , Ltd.