Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> TMEM16AInhibitorsRevealTMEM16A(T16Ainh-A01)

TMEM16AInhibitorsRevealTMEM16A(T16Ainh-A01)

TMEM16AInhibitorsRevealTMEM16A(T16Ainh-A01) price.
  • $32 - $2200
  • Product name: TMEM16AInhibitorsRevealTMEM16A(T16Ainh-A01)
  • CAS: 552309-42-9
  • MF: C19H20N4O3S2
  • MW: 416.52
  • EINECS:
  • MDL Number:MFCD29770791
  • Synonyms:TMEM16AInhibitorsRevealTMEM16A(T16Ainh-A01);T16Ainh-A01;2-[(5-Ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]-N-[4-(4-methoxyphenyl)-2-thiazolyl]acetamide;TMEM16A Inhibitor, T16Ainh-A01 - Calbiochem;Acetamide, 2-[(5-ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]-N-[4-(4-methoxyphenyl)-2-thiazolyl]-;inhibitor of TMEM16A;2-((5-Ethyl-4-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio)-N-(4-(4-methoxyphenyl)thiazol-2-yl)acetamide;inhibit,T16AinhA01,Chloride Channel,T16Ainh-A01,T-16Ainh-A01,T16Ainh A01,Cl-Channels,Inhibitor
21 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5MG
  • 10mg
  • 50
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0001545
  • Product descriptionT-16-AINH-A-01 98.00%
  • Packaging5MG
  • Price$504.82
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5635
  • Product descriptionT16Ainh-A01
  • Packaging10mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5635
  • Product descriptionT16Ainh-A01
  • Packaging50mg
  • Price$261
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18518
  • Product descriptionT16A(inh)-A01 ≥95%
  • Packaging5mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18518
  • Product descriptionT16A(inh)-A01 ≥95%
  • Packaging10mg
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18518
  • Product descriptionT16A(inh)-A01 ≥95%
  • Packaging50mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019784
  • Product descriptionT16Ainh-A01 >99.0%
  • Packaging1mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019784
  • Product descriptionT16Ainh-A01 >99.0%
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0019784
  • Product descriptionT16Ainh-A01 >99.0%
  • Packaging10mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC21956
  • Product descriptionT16Ainh-A01 >98%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC21956
  • Product descriptionT16Ainh-A01 >98%
  • Packaging250mg
  • Price$1100
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC21956
  • Product descriptionT16Ainh-A01 >98%
  • Packaging1g
  • Price$2200
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number57882
  • Product description2-[(5-Ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]-N-[4-(4-methoxyphenyl)-2-thiazolyl]acetamide
  • Packaging10mg
  • Price$640
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0493
  • Product descriptionT16Ainh-A01 ≥95% (HPLC)
  • Packaging10mg
  • Price$47.34
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number613551
  • Product descriptionTMEM16A Inhibitor, T16Ainh-A01 - Calbiochem
  • Packaging5mg
  • Price$230
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0493
  • Product descriptionT16Ainh-A01 ≥95% (HPLC)
  • Packaging50mg
  • Price$320
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation INB0001545 T-16-AINH-A-01 98.00% 5MG $504.82 2021-12-16 Buy
ApexBio Technology B5635 T16Ainh-A01 10mg $67 2021-12-16 Buy
ApexBio Technology B5635 T16Ainh-A01 50mg $261 2021-12-16 Buy
Cayman Chemical 18518 T16A(inh)-A01 ≥95% 5mg $32 2024-03-01 Buy
Cayman Chemical 18518 T16A(inh)-A01 ≥95% 10mg $61 2024-03-01 Buy
Cayman Chemical 18518 T16A(inh)-A01 ≥95% 50mg $230 2024-03-01 Buy
ChemScene CS-0019784 T16Ainh-A01 >99.0% 1mg $70 2021-12-16 Buy
ChemScene CS-0019784 T16Ainh-A01 >99.0% 5mg $150 2021-12-16 Buy
ChemScene CS-0019784 T16Ainh-A01 >99.0% 10mg $250 2021-12-16 Buy
DC Chemicals DC21956 T16Ainh-A01 >98% 100mg $600 2021-12-16 Buy
DC Chemicals DC21956 T16Ainh-A01 >98% 250mg $1100 2021-12-16 Buy
DC Chemicals DC21956 T16Ainh-A01 >98% 1g $2200 2021-12-16 Buy
Medical Isotopes, Inc. 57882 2-[(5-Ethyl-1,6-dihydro-4-methyl-6-oxo-2-pyrimidinyl)thio]-N-[4-(4-methoxyphenyl)-2-thiazolyl]acetamide 10mg $640 2021-12-16 Buy
Sigma-Aldrich SML0493 T16Ainh-A01 ≥95% (HPLC) 10mg $47.34 2024-03-01 Buy
Sigma-Aldrich 613551 TMEM16A Inhibitor, T16Ainh-A01 - Calbiochem 5mg $230 2024-03-01 Buy
Sigma-Aldrich SML0493 T16Ainh-A01 ≥95% (HPLC) 50mg $320 2024-03-01 Buy

Properties

Melting point :211-212°C (dec.)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :7.20±0.50(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

Transmembrane protein 16A (TMEM16A, also known as anoctamin-1) is a calcium-activated chloride channel (CaCC) with roles in transepithelial anion transport and smooth muscle contraction. T16A(inh)-A01 is an aminophenylthiazole that inhibits transient TMEM16A-mediated chloride currents with an IC50 value of ~1 μM. Its inhibitory effects are independent of voltage and do not prolong the rate of TMEM16A current deactivation. T16A(inh)-A01 blocks CaCC activity in vascular smooth muscle cells and relaxes mouse and human blood vessels. It also inhibits the proliferation of pancreatic cancer and squamous carcinoma cells in culture.