4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE
![4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE price.](/CAS/GIF/607737-87-1.gif)
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- $40 - $1600
- Product name: 4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE
- CAS: 607737-87-1
- MF: C18H14N4
- MW: 286.33
- EINECS:
- MDL Number:MFCD07367791
- Synonyms:4-[3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL]-QUINOLINE;A 77-01;A-77-01;A77-01;4-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]quinoline A 77-01;4-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoline;CS-1775;4-[5-(6-methylpyridin-2-yl)-1~{H}-pyrazol-4-yl]quinoline
18 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
Package
- 1mg
- 5
- 5mg
- 1g
- 25
- 10mg
- 25mg
- 50MG
- 500MG
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number3271AH
- Product descriptionA77-01
- Packaging25mg
- Price$1022
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA869452
- Product description4-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)quinoline 98+%
- Packaging25mg
- Price$539
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0150287
- Product description4-(3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL)-QUINOLINE 95.00%
- Packaging50MG
- Price$704.55
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0150287
- Product description4-(3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL)-QUINOLINE 95.00%
- Packaging500MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3132
- Product descriptionA77-01
- Packaging10mg
- Price$102
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3132
- Product descriptionA77-01
- Packaging10mM(in 1mL DMSO)
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3132
- Product descriptionA77-01
- Packaging25mg
- Price$187
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18396
- Product descriptionA-77-01 ≥98%
- Packaging1mg
- Price$40
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18396
- Product descriptionA-77-01 ≥98%
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18396
- Product descriptionA-77-01 ≥98%
- Packaging10mg
- Price$236
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18396
- Product descriptionA-77-01 ≥98%
- Packaging25mg
- Price$492
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-1564
- Product descriptionA77-01 99.55%
- Packaging5mg
- Price$144
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1564
- Product descriptionA77-01 99.55%
- Packaging10mg
- Price$216
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001307
- Product descriptionA77-01 98+%
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001307
- Product descriptionA77-01 98+%
- Packaging10mg
- Price$126
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC8020
- Product descriptionA77-01 >98%
- Packaging1g
- Price$1600
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3271AH | A77-01 | 25mg | $1022 | 2021-12-16 | Buy |
| Ambeed | A869452 | 4-(3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl)quinoline 98+% | 25mg | $539 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0150287 | 4-(3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL)-QUINOLINE 95.00% | 50MG | $704.55 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0150287 | 4-(3-(6-METHYL-2-PYRIDINYL)-1H-PYRAZOL-4-YL)-QUINOLINE 95.00% | 500MG | $1593.9 | 2021-12-16 | Buy |
| ApexBio Technology | A3132 | A77-01 | 10mg | $102 | 2021-12-16 | Buy |
| ApexBio Technology | A3132 | A77-01 | 10mM(in 1mL DMSO) | $120 | 2021-12-16 | Buy |
| ApexBio Technology | A3132 | A77-01 | 25mg | $187 | 2021-12-16 | Buy |
| Cayman Chemical | 18396 | A-77-01 ≥98% | 1mg | $40 | 2024-03-01 | Buy |
| Cayman Chemical | 18396 | A-77-01 ≥98% | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 18396 | A-77-01 ≥98% | 10mg | $236 | 2024-03-01 | Buy |
| Cayman Chemical | 18396 | A-77-01 ≥98% | 25mg | $492 | 2024-03-01 | Buy |
| ChemScene | CS-1564 | A77-01 99.55% | 5mg | $144 | 2021-12-16 | Buy |
| ChemScene | CS-1564 | A77-01 99.55% | 10mg | $216 | 2021-12-16 | Buy |
| Crysdot | CD31001307 | A77-01 98+% | 5mg | $84 | 2021-12-16 | Buy |
| Crysdot | CD31001307 | A77-01 98+% | 10mg | $126 | 2021-12-16 | Buy |
| DC Chemicals | DC8020 | A77-01 >98% | 1g | $1600 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥14.3 mg/mL in DMSO; ≥8.84 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
color :Off-white to light yellow
solubility :insoluble in H2O; ≥14.3 mg/mL in DMSO; ≥8.84 mg/mL in EtOH with gentle warming and ultrasonic
form :solid
color :Off-white to light yellow
Safety Information
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Description
A-77-01 is a potent inhibitor of the TGF-β1 receptor ALK5 (IC50 = 25 nM). It has no effects on BMP-regulated transcriptional activity or MAPK pathways. A-77-01 efficiently prevents the growth inhibitory effects of TGF-β on lung epithelial Mv1Lu cells. It completely blocks phosphorylation of SMAD2 by TGF-β in human keratinocyte HaCaT cells at 1 μM. A-77-01 prevents morphological and gene expression changes characteristic of epithelial-to-mesenchymal transition in NMuMG cells treated with TGF-β.More related product prices
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