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ChemicalBook >> CAS DataBase List >> 7α,25-dihydroxy Cholesterol

7α,25-dihydroxy Cholesterol

7α,25-dihydroxy Cholesterol price.
  • $57 - $1490
  • Product name: 7α,25-dihydroxy Cholesterol
  • CAS: 64907-22-8
  • MF: C27H46O3
  • MW: 418.65
  • EINECS:
  • MDL Number:MFCD20488904
  • Synonyms:7-alpha,25-Dihydroxycholesterol;3β,7α,25-Trihydroxycholest-5-ene;5-Cholesten-3β,7α,25-triol;25-dihydroxycholesterol;7Α,25-DIHYDROXYCHOLESTEROL;7Α;25-DIHYDROXYCHOLESTEROL;(3β,7α)-Cholest-5-ene-3,7,25-triol;7α,25-OHC;7α,25-dihydroxy Cholesterol
16 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
Package
  • 10
  • 1mg
  • 2.5mg
  • 5MG
  • 10mg
  • 25mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberSHG0005095
  • Product description7-ALPHA-25-DIHYDROXY CHOLESTEROL 95.00%
  • Packaging5MG
  • Price$500.04
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4241
  • Product description7α,25-dihydroxyCholesterol
  • Packaging1mg
  • Price$62
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4241
  • Product description7α,25-dihydroxyCholesterol
  • Packaging5mg
  • Price$297
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4241
  • Product description7α,25-dihydroxyCholesterol
  • Packaging10mg
  • Price$562
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11032
  • Product description7α,25-dihydroxy Cholesterol ≥95%
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11032
  • Product description7α,25-dihydroxy Cholesterol ≥95%
  • Packaging5mg
  • Price$262
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11032
  • Product description7α,25-dihydroxy Cholesterol ≥95%
  • Packaging10mg
  • Price$493
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0064788
  • Product description7α,25-Dihydroxycholesterol >99.0%
  • Packaging1mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0064788
  • Product description7α,25-Dihydroxycholesterol >99.0%
  • Packaging5mg
  • Price$680
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0064788
  • Product description7α,25-Dihydroxycholesterol >99.0%
  • Packaging10mg
  • Price$1150
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number72836
  • Product description3β,7α,25-Trihydroxycholest-5-ene
  • Packaging5mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0541
  • Product description7α,25-Dihydroxycholesterol ≥98% (HPLC)
  • Packaging5mg
  • Price$370
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0541
  • Product description7α,25-Dihydroxycholesterol ≥98% (HPLC)
  • Packaging25mg
  • Price$1490
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number6277
  • Product description7alpha,25-Dihydroxycholesterol ≥98%(HPLC)
  • Packaging10
  • Price$368
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT795075
  • Product description3β,7α,25-Trihydroxycholest-5-ene
  • Packaging2.5mg
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT795075
  • Product description3β,7α,25-Trihydroxycholest-5-ene
  • Packaging5mg
  • Price$210
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation SHG0005095 7-ALPHA-25-DIHYDROXY CHOLESTEROL 95.00% 5MG $500.04 2021-12-16 Buy
ApexBio Technology C4241 7α,25-dihydroxyCholesterol 1mg $62 2021-12-16 Buy
ApexBio Technology C4241 7α,25-dihydroxyCholesterol 5mg $297 2021-12-16 Buy
ApexBio Technology C4241 7α,25-dihydroxyCholesterol 10mg $562 2021-12-16 Buy
Cayman Chemical 11032 7α,25-dihydroxy Cholesterol ≥95% 1mg $57 2024-03-01 Buy
Cayman Chemical 11032 7α,25-dihydroxy Cholesterol ≥95% 5mg $262 2024-03-01 Buy
Cayman Chemical 11032 7α,25-dihydroxy Cholesterol ≥95% 10mg $493 2024-03-01 Buy
ChemScene CS-0064788 7α,25-Dihydroxycholesterol >99.0% 1mg $225 2021-12-16 Buy
ChemScene CS-0064788 7α,25-Dihydroxycholesterol >99.0% 5mg $680 2021-12-16 Buy
ChemScene CS-0064788 7α,25-Dihydroxycholesterol >99.0% 10mg $1150 2021-12-16 Buy
Medical Isotopes, Inc. 72836 3β,7α,25-Trihydroxycholest-5-ene 5mg $700 2021-12-16 Buy
Sigma-Aldrich SML0541 7α,25-Dihydroxycholesterol ≥98% (HPLC) 5mg $370 2024-03-01 Buy
Sigma-Aldrich SML0541 7α,25-Dihydroxycholesterol ≥98% (HPLC) 25mg $1490 2024-03-01 Buy
Tocris 6277 7alpha,25-Dihydroxycholesterol ≥98%(HPLC) 10 $368 2021-12-16 Buy
TRC T795075 3β,7α,25-Trihydroxycholest-5-ene 2.5mg $115 2021-12-16 Buy
TRC T795075 3β,7α,25-Trihydroxycholest-5-ene 5mg $210 2021-12-16 Buy

Properties

Boiling point :548.5±35.0 °C(Predicted)
Density :1.08±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL (clear solution)
form :powder
pka :14.11±0.70(Predicted)
color :white to beige

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

GPR183 (also known as Epstein-Barr virus-induced gene 2) is an orphan G protein-coupled receptor (GPCR) that is highly expressed in spleen and is required for humoral immune responses, including B cell migration and T cell-dependent antibody production. 7α,25-dihydroxy Cholesterol (7α,25-DHC) is a potent agonist of GPR183 that induces specific activation of the receptor with an EC50 value of 50 nM (Kd = 450 pM). At concentrations below 3 μM, it does not show any appreciable binding activity when tested against eight different nuclear hormone receptors including LXR and thirty-one different G protein-coupled receptors in a panel of reporter gene assays. 7α,25-DHC can act as a potent chemokine, affecting migration of immune cells expressing GPR183 both in vitro (EC50 = 500 pM) and in vivo.