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ChemicalBook >> CAS DataBase List >> N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea

N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea

N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea price.
  • $32 - $767
  • Product name: N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea
  • CAS: 685506-42-7
  • MF: C17H21N3O4S
  • MW: 363.43
  • EINECS:
  • MDL Number:MFCD02679009
  • Synonyms:GSK 264220A;N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea;1-(2-methyl-5-piperidin-1-ylsulfonylfuran-3-yl)-3-phenylurea;Urea, N-[2-methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenyl-
14 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 50
  • 10mg
  • 25mg
  • 2x25mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number1744CJ
  • Product description3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1744CJ
  • Product description3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea
  • Packaging5mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1744CJ
  • Product description3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea
  • Packaging10mg
  • Price$268
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1744CJ
  • Product description3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea
  • Packaging25mg
  • Price$479
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5473
  • Product descriptionGSK264220A
  • Packaging10mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3213
  • Product descriptionGSK264220A 99%
  • Packaging2x25mg
  • Price$572
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13009
  • Product descriptionGSK264220A ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13009
  • Product descriptionGSK264220A ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13009
  • Product descriptionGSK264220A ≥98%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13009
  • Product descriptionGSK264220A ≥98%
  • Packaging25mg
  • Price$343
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number3752
  • Product descriptionGSK264220A ≥98%(HPLC)
  • Packaging10
  • Price$182
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3752
  • Product descriptionGSK264220A ≥98%(HPLC)
  • Packaging50
  • Price$767
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberG797608
  • Product descriptionGSK264220A
  • Packaging100mg
  • Price$605
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255406
  • Product descriptionGSK 264220A
  • Packaging10mg
  • Price$423
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1744CJ 3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea 1mg $133 2021-12-16 Buy
AK Scientific 1744CJ 3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea 5mg $226 2021-12-16 Buy
AK Scientific 1744CJ 3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea 10mg $268 2021-12-16 Buy
AK Scientific 1744CJ 3-[2-Methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea 25mg $479 2021-12-16 Buy
ApexBio Technology B5473 GSK264220A 10mg $266 2021-12-16 Buy
Axon Medchem Axon3213 GSK264220A 99% 2x25mg $572 2021-12-16 Buy
Cayman Chemical 13009 GSK264220A ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 13009 GSK264220A ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 13009 GSK264220A ≥98% 10mg $153 2024-03-01 Buy
Cayman Chemical 13009 GSK264220A ≥98% 25mg $343 2024-03-01 Buy
Tocris 3752 GSK264220A ≥98%(HPLC) 10 $182 2021-12-16 Buy
Tocris 3752 GSK264220A ≥98%(HPLC) 50 $767 2021-12-16 Buy
TRC G797608 GSK264220A 100mg $605 2021-12-16 Buy
Usbiological 255406 GSK 264220A 10mg $423 2021-12-16 Buy

Properties

Density :1.375±0.06 g/cm3(Predicted)
storage temp. :Store at +4°C
solubility :Soluble to 100 mM in DMSO and to 10 mM in ethanol
form :Powder
pka :13.63±0.70(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Endothelial lipase, a member of the triglyceride lipase gene family expressed in endothelial cells, prefers phospholipid-enriched high-density lipoprotein (HDL) over triglyceride as substrate. GSK264220A is a potent inhibitor of endothelial lipase (IC50 = 16 nM). Levels of HDL cholesterol are inversely correlated with endothelial lipase protein activity. Therefore, inhibition of endothelial lipase by compounds like GSK264220A may be expected to increase HDL levels and potentially decrease the risk of cardiovascular disease.