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ChemicalBook >> CAS DataBase List >> alpha-(difluoromethyl)arginine

alpha-(difluoromethyl)arginine

alpha-(difluoromethyl)arginine price.
  • $32 - $290
  • Product name: alpha-(difluoromethyl)arginine
  • CAS: 69955-43-7
  • MF: C7H14F2N4O2
  • MW: 224.21
  • EINECS:
  • MDL Number:MFCD18252556
  • Synonyms:alpha-(difluoromethyl)arginine;2-(Difluoromethyl)arginine;a-(Difluoromethyl)-DL-arginine;a-Difluoromethylarginine;DFMA;DL-a-(Difluoromethyl)arginine;RMI 71897;DL-α-(Difluoromethyl)arginine
6 prices
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  • AK Scientific
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product number8641CA
  • Product description2-(Difluoromethyl)arginine
  • Packaging5mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16415
  • Product descriptionα-(difluoromethyl)-DL-Arginine ≥95%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16415
  • Product descriptionα-(difluoromethyl)-DL-Arginine ≥95%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16415
  • Product descriptionα-(difluoromethyl)-DL-Arginine ≥95%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16415
  • Product descriptionα-(difluoromethyl)-DL-Arginine ≥95%
  • Packaging25mg
  • Price$290
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberD445840
  • Product descriptionDL-α-(Difluoromethyl)arginine
  • Packaging25mg
  • Price$180
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8641CA 2-(Difluoromethyl)arginine 5mg $201 2021-12-16 Buy
Cayman Chemical 16415 α-(difluoromethyl)-DL-Arginine ≥95% 1mg $32 2024-03-01 Buy
Cayman Chemical 16415 α-(difluoromethyl)-DL-Arginine ≥95% 5mg $93 2024-03-01 Buy
Cayman Chemical 16415 α-(difluoromethyl)-DL-Arginine ≥95% 10mg $153 2024-03-01 Buy
Cayman Chemical 16415 α-(difluoromethyl)-DL-Arginine ≥95% 25mg $290 2024-03-01 Buy
TRC D445840 DL-α-(Difluoromethyl)arginine 25mg $180 2021-12-16 Buy

Properties

Melting point :>160°C (dec.)
Boiling point :406.9±55.0 °C(Predicted)
Density :1.53±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Methanol (Very Slightly, Heated), Water (Slightly)
form :Solid
pka :1.26±0.44(Predicted)
color :White to Off-White
Stability :Hygroscopic

Safety Information

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Description

Bacteria synthesize the cellular growth factor putrescine through a number of pathways. One pathway involves the decarboxylation of arginine by arginine decarboxylase to produce agmatine, which is then degraded to putrescine. While important for various cellular processes (e.g., cell division, differentiation, environmental stress responses) in all living organisms, including plants, high levels of this polyamine can be toxic. α-(difluoromethyl)-DL-Arginine (DFMA) is an enzyme-activated, irreversible inhibitor of the arginine decarboxylases of E. coli (Ki = 800 μM), P. aeruginosa, and K. pneumoniae. At 0.01 mM, it has been shown to prevent the osmotic stress-induced increase in arginine decarboxylase activity and putrescine synthesis in oat leaf cells. DFMA can also reduce the growth of T. cruzi in mammalian host cells at a minimal concentration of 10 mM and prevent the growth of C. parvum in a T cell receptor alpha-deficient mouse model when combined with various polyamine analogs.

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