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ChemicalBook >> CAS DataBase List >> pyridoxal isonicotinoyl hydrazone

pyridoxal isonicotinoyl hydrazone

pyridoxal isonicotinoyl hydrazone price.
  • $42 - $1356.6
  • Product name: pyridoxal isonicotinoyl hydrazone
  • CAS: 737-86-0
  • MF: C14H14N4O3
  • MW: 286.29
  • EINECS:
  • MDL Number:MFCD00763290
  • Synonyms:Pyridoxal isonicotinoyl hydrazone (PIH);NSC 77674;PIH(Pyridoxal isonicotinoyl hydrazine);PIH - CAS 737-86-0 - Calbiochem;Pyridoxal isonicotinoyl hydrazine;4-Pyridinecarboxylic acid, 2-[[3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl]methylene]hydrazide;N'-((3-Hydroxy-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene)isonicotinohydrazide;inhibit,pyridoxal isonicotinoyl hydrazone,Inhibitor
14 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 50mg
  • 528110-50MG
  • 5MG
  • 100mg
  • 10mM(in 1mL DMSO)
  • 250mg
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCHM0312134
  • Product descriptionPYRIDOXAL ISONICOTINOYL HYDRAZONE 95.00%
  • Packaging5MG
  • Price$495.09
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6060
  • Product descriptionPyridoxalisonicotinoylhydrazone
  • Packaging10mM(in 1mL DMSO)
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6060
  • Product descriptionPyridoxalisonicotinoylhydrazone
  • Packaging50mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573419
  • Product descriptionPIH (Pyridoxal isonicotinoyl hydrazine) >98%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573419
  • Product descriptionPIH (Pyridoxal isonicotinoyl hydrazine) >98%
  • Packaging250mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573419
  • Product descriptionPIH (Pyridoxal isonicotinoyl hydrazine) >98%
  • Packaging1g
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19357
  • Product descriptionPyridoxal isonicotinoyl hydrazone ≥99%
  • Packaging50mg
  • Price$141
  • Updated2024-03-01
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN23890
  • Product descriptionPyridoxalisonicotinoylhydrazone
  • Packaging50mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC20241
  • Product descriptionPIH(Pyridoxalisonicotinoylhydrazine) >98%
  • Packaging100mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC20241
  • Product descriptionPIH(Pyridoxalisonicotinoylhydrazine) >98%
  • Packaging250mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC20241
  • Product descriptionPIH(Pyridoxalisonicotinoylhydrazine) >98%
  • Packaging1g
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number528110-M
  • Product descriptionPIH - CAS 737-86-0 - Calbiochem A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class.
  • Packaging50mg
  • Price$210
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number528110-M
  • Product descriptionPIH - CAS 737-86-0 - Calbiochem A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class.
  • Packaging528110-50MG
  • Price$275
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP991723
  • Product descriptionPyridoxalIsonicotinoylHydrazone
  • Packaging100mg
  • Price$335
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation CHM0312134 PYRIDOXAL ISONICOTINOYL HYDRAZONE 95.00% 5MG $495.09 2021-12-16 Buy
ApexBio Technology B6060 Pyridoxalisonicotinoylhydrazone 10mM(in 1mL DMSO) $42 2021-12-16 Buy
ApexBio Technology B6060 Pyridoxalisonicotinoylhydrazone 50mg $105 2021-12-16 Buy
Biorbyt Ltd orb573419 PIH (Pyridoxal isonicotinoyl hydrazine) >98% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb573419 PIH (Pyridoxal isonicotinoyl hydrazine) >98% 250mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb573419 PIH (Pyridoxal isonicotinoyl hydrazine) >98% 1g $1356.6 2021-12-16 Buy
Cayman Chemical 19357 Pyridoxal isonicotinoyl hydrazone ≥99% 50mg $141 2024-03-01 Buy
CSNpharm CSN23890 Pyridoxalisonicotinoylhydrazone 50mg $92 2021-12-16 Buy
DC Chemicals DC20241 PIH(Pyridoxalisonicotinoylhydrazine) >98% 100mg $250 2021-12-16 Buy
DC Chemicals DC20241 PIH(Pyridoxalisonicotinoylhydrazine) >98% 250mg $450 2021-12-16 Buy
DC Chemicals DC20241 PIH(Pyridoxalisonicotinoylhydrazine) >98% 1g $900 2021-12-16 Buy
Sigma-Aldrich 528110-M PIH - CAS 737-86-0 - Calbiochem A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class. 50mg $210 2022-05-15 Buy
Sigma-Aldrich 528110-M PIH - CAS 737-86-0 - Calbiochem A cell-permeable, non-toxic tridendate iron (Fe3+) chelator of the aroyl hydrazone class. 528110-50MG $275 2024-03-01 Buy
TRC P991723 PyridoxalIsonicotinoylHydrazone 100mg $335 2021-12-16 Buy

Properties

Melting point :261-262 °C (decomp)
Density :1.35±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :DMF: 1 mg/ml; DMSO: 5 mg/ml; Ethanol: 0.5 mg/ml
form :Yellow solid
pka :8.04±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Pyridoxal isonicotinoyl hydrazine is a lipophilic, nontoxic, iron-chelating agent that shows high iron chelation efficacy both in vitro in cell culture models and in vivo in rats and mice. Because iron is a crucial component of metabolic pathways involved in DNA synthesis, cancerous cells have a high iron requirement due to rapid rates of proliferation. While pyridoxal isonicotinoyl hydrazine exhibits low anticancer activity, its analogs demonstrate antiproliferative effects in a range of tumor cells.

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