(9E,12Z)-10-Nitrooctadecadienoic acid
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- $48 - $371
- Product name: (9E,12Z)-10-Nitrooctadecadienoic acid
- CAS: 774603-04-2
- MF: C18H31NO4
- MW: 325.44
- EINECS:
- MDL Number:
- Synonyms:(9E,12Z)-10-Nitrooctadecadienoic acid;10-Nitrolinoleic acid;10-Nitrolinoleate;10-Nitro-9Z,12Z-octadecadienoic acid;LELVHAQTWXTCLY-XYWKCAQWSA-N;9,12-Octadecadienoic acid, 10-nitro-, (9E,12Z)-;10-Nitro-9(E)-12(Z)-Octadecadienoic acid;10 Nitrolinoleic acid,10Nitrolinoleic acid
3 prices
Selected condition：
Brand
- Cayman Chemical
Package
- 100μg
- 500μg
- 1mg
- ManufacturerCayman Chemical
- Product number10037
- Product description10-Nitrolinoleate ≥95%
- Packaging100μg
- Price$48
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10037
- Product description10-Nitrolinoleate ≥95%
- Packaging500μg
- Price$210
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10037
- Product description10-Nitrolinoleate ≥95%
- Packaging1mg
- Price$371
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 10037 | 10-Nitrolinoleate ≥95% | 100μg | $48 | 2024-03-01 | Buy |
| Cayman Chemical | 10037 | 10-Nitrolinoleate ≥95% | 500μg | $210 | 2024-03-01 | Buy |
| Cayman Chemical | 10037 | 10-Nitrolinoleate ≥95% | 1mg | $371 | 2024-03-01 | Buy |
Properties
Boiling point :452.2±33.0 °C(Predicted)
Density :1.016±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka :4.77±0.10(Predicted)
Density :1.016±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
pka :4.77±0.10(Predicted)
Safety Information
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| Signal word: | Danger | |||||||
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Description
10-Nitrolinoleate is the product of nitration of linoleate by NO-derived reactive species. Other nitrolinoleates detected in human plasma and urine include 9-, 12-, and 13-nitrolinoleate. Nitrolinoleates activate peroxisome proliferator-activated receptor γ (PPARγ; Ki = 133 nM), inducing CD36 expression in macrophages, adipocyte differentiation, and glucose uptake. Nitrolinoleates can also be metabolized by smooth muscle cells to produce nitrite derivatives which in turn form NO, leading to increased cGMP production and smooth muscle relaxation. Through the same mechanism, nitrolinoleate-derived NO suppresses leukocyte adhesion, in part through nitrosation of CD40. Alteratively, nitrolinoleates can act independently of NO/cGMP and PPARγ signaling to suppress neutrophil and macrophage functions.Suppliers and manufacturers
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