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ChemicalBook >> CAS DataBase List >> 1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine

1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine

1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine price.
  • $49 - $2023
  • Product name: 1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine
  • CAS: 831234-13-0
  • MF: C19H17N3O
  • MW: 303.36
  • EINECS:
  • MDL Number:MFCD06609959
  • Synonyms:1-benzyl-N-(furan-2-ylmethyl)benzimidazol-2-amine;AC1903;1H-Benzimidazol-2-amine, N-(2-furanylmethyl)-1-(phenylmethyl)-;AC1903 >=98% (HPLC);1-benzyl-N-(furan-2-ylmethyl)-1H-benzo[d]imidazol-2-amine;1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine;Inhibitor,glomerulosclerosis,proteinuria,inhibit,TRP Channel,ros,focal segmental,AC 1903,Transient receptor potential channels,AC-1903,FSGS,AC1903,kidney disease,podocyte loss,HEK-293;AC1903 AC-1903
Price19 Properties Safety Information Description
19 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • Biorbyt Ltd
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Tocris
Package
  • 50mg
  • 100mg
  • 250mg
  • 25
  • 5mg
  • 10mg
  • 25mg
  • 1g
  • ManufacturerAK Scientific
  • Product number9847CC
  • Product description1-Benzyl-N-(furan-2-ylmethyl)-1H-benzimidazol-2-amine
  • Packaging1g
  • Price$1429
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1059027
  • Product description1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+%
  • Packaging5mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1059027
  • Product description1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+%
  • Packaging10mg
  • Price$246
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1059027
  • Product description1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+%
  • Packaging25mg
  • Price$319
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1059027
  • Product description1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+%
  • Packaging50mg
  • Price$414
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1059027
  • Product description1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+%
  • Packaging100mg
  • Price$538
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1059027
  • Product description1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+%
  • Packaging250mg
  • Price$814
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1059027
  • Product description1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+%
  • Packaging1g
  • Price$2023
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546177
  • Product descriptionAC1903 >98%
  • Packaging10mg
  • Price$190.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546177
  • Product descriptionAC1903 >98%
  • Packaging50mg
  • Price$521.9
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25324
  • Product descriptionAC1903 ≥95%
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25324
  • Product descriptionAC1903 ≥95%
  • Packaging10mg
  • Price$87
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0081483
  • Product descriptionAC1903 98.64%
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0081483
  • Product descriptionAC1903 98.64%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0081483
  • Product descriptionAC1903 98.64%
  • Packaging25mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0081483
  • Product descriptionAC1903 98.64%
  • Packaging50mg
  • Price$420
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9847CC 1-Benzyl-N-(furan-2-ylmethyl)-1H-benzimidazol-2-amine 1g $1429 2021-12-16 Buy
Ambeed A1059027 1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+% 5mg $190 2021-12-16 Buy
Ambeed A1059027 1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+% 10mg $246 2021-12-16 Buy
Ambeed A1059027 1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+% 25mg $319 2021-12-16 Buy
Ambeed A1059027 1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+% 50mg $414 2021-12-16 Buy
Ambeed A1059027 1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+% 100mg $538 2021-12-16 Buy
Ambeed A1059027 1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+% 250mg $814 2021-12-16 Buy
Ambeed A1059027 1-Benzyl-N-[(furan-2-yl)methyl]-1H-1,3-benzodiazol-2-amine 98+% 1g $2023 2021-12-16 Buy
Biorbyt Ltd orb546177 AC1903 >98% 10mg $190.4 2021-12-16 Buy
Biorbyt Ltd orb546177 AC1903 >98% 50mg $521.9 2021-12-16 Buy
Cayman Chemical 25324 AC1903 ≥95% 5mg $49 2024-03-01 Buy
Cayman Chemical 25324 AC1903 ≥95% 10mg $87 2024-03-01 Buy
ChemScene CS-0081483 AC1903 98.64% 5mg $65 2021-12-16 Buy
ChemScene CS-0081483 AC1903 98.64% 10mg $110 2021-12-16 Buy
ChemScene CS-0081483 AC1903 98.64% 25mg $240 2021-12-16 Buy
ChemScene CS-0081483 AC1903 98.64% 50mg $420 2021-12-16 Buy
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Properties

Boiling point :512.4±60.0 °C(Predicted)
Density :1.20±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 25 mg/ml)
pka :6.09±0.10(Predicted)
form :solid
color :Beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

AC1903 is an inhibitor of transient receptor potential canonical channel 5 (TRPC5; IC50 = 14.7 μM). It is selective for TRPC5 over TRPC4 and TRPC6 at concentrations up to 100 and 30 μM, respectively. It inhibits TRPC5 in a concentration-dependent manner in HEK293 cells when used at concentrations ranging from 1 to 100 μM. AC1903 (30 μM) inhibits angiotensin II-induced production of reactive oxygen species (ROS) in wild-type podocytes and podocytes expressing a mutant angiotensin II type 1 (AT1) receptor that cannot be inactivated and endocytosed. It also suppresses proteinuria as well as reduces pseudocyst formation and podocyte loss in an AT1 receptor transgenic rat model of kidney disease when administered at a dose of 50 mg/kg twice per day. In a model of hypertension-induced focal segmental glomerulosclerosis (FSGS) using Dahl salt-sensitive rats, AC1903 decreases the rate of proteinuria when administered at the beginning of a high-salt diet and prevents progression when administered one week following initiation of a high-salt diet.

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Zhejiang J&C Biological Technology Co.,Limited
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Aladdin Scientific Suzhou Zhixin Biotechnology Co., Ltd. Nantong MYBio-pharm. Co., Ltd. Shanghai Lollane Biological Technology Co.,Ltd. BOC Sciences ShangHai Angti Biotechnology Co., Ltd.