2-Acetylfuro-1,4-naphthoquinone
- $17 - $1650
- Product name: 2-Acetylfuro-1,4-naphthoquinone
- CAS: 83280-65-3
- MF: C14H8O4
- MW: 240.21
- EINECS:
- MDL Number:MFCD28155270
- Synonyms:2-Acetylfuro-1,4-naphthoquinone;Napabucasin;2-Acetylfuro-1,4-phthoquinone;Napabucasin (BBI608);2-acetylnaphtho[2,3-b]furan-4,9-quinone;Remimazolam besylate;Naphtho[2,3-b]furan-4,9-dione, 2-acetyl-;2-acetylbenzo[f][1]benzofuran-4,9-dione
38 prices
Selected condition:
Brand
- Abosyn
- Ambeed
- American Custom Chemicals Corporation
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 50
- 500mg
- 0.5g
- 1g
- ManufacturerAbosyn
- Product number10-3525
- Product description2-acetylfuro-1,4-naphthoquinone 95%-98%
- Packaging0.5g
- Price$395
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113651
- Product descriptionNapabucasin 98+%
- Packaging1mg
- Price$17
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113651
- Product descriptionNapabucasin 98+%
- Packaging5mg
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113651
- Product descriptionNapabucasin 98+%
- Packaging10mg
- Price$36
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113651
- Product descriptionNapabucasin 98+%
- Packaging50mg
- Price$61
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113651
- Product descriptionNapabucasin 98+%
- Packaging100mg
- Price$97
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113651
- Product descriptionNapabucasin 98+%
- Packaging250mg
- Price$149
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA113651
- Product descriptionNapabucasin 98+%
- Packaging1g
- Price$371
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004695
- Product description2-ACETYLNAPHTHO[2,3-B]FURAN-4,9-DIONE 95.00%
- Packaging5MG
- Price$496.42
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2517
- Product descriptionNapabucasin-BBI608|FNQ 99%
- Packaging10mg
- Price$115.5
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2517
- Product descriptionNapabucasin-BBI608|FNQ 99%
- Packaging50mg
- Price$445.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546182
- Product descriptionNapabucasin >98%
- Packaging5mg
- Price$168.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546182
- Product descriptionNapabucasin >98%
- Packaging25mg
- Price$472.6
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22255
- Product descriptionNapabucasin ≥98%
- Packaging5mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22255
- Product descriptionNapabucasin ≥98%
- Packaging10mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22255
- Product descriptionNapabucasin ≥98%
- Packaging25mg
- Price$268
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Abosyn | 10-3525 | 2-acetylfuro-1,4-naphthoquinone 95%-98% | 0.5g | $395 | 2021-12-16 | Buy |
Ambeed | A113651 | Napabucasin 98+% | 1mg | $17 | 2021-12-16 | Buy |
Ambeed | A113651 | Napabucasin 98+% | 5mg | $28 | 2021-12-16 | Buy |
Ambeed | A113651 | Napabucasin 98+% | 10mg | $36 | 2021-12-16 | Buy |
Ambeed | A113651 | Napabucasin 98+% | 50mg | $61 | 2021-12-16 | Buy |
Ambeed | A113651 | Napabucasin 98+% | 100mg | $97 | 2021-12-16 | Buy |
Ambeed | A113651 | Napabucasin 98+% | 250mg | $149 | 2021-12-16 | Buy |
Ambeed | A113651 | Napabucasin 98+% | 1g | $371 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0004695 | 2-ACETYLNAPHTHO[2,3-B]FURAN-4,9-DIONE 95.00% | 5MG | $496.42 | 2021-12-16 | Buy |
Axon Medchem | Axon2517 | Napabucasin-BBI608|FNQ 99% | 10mg | $115.5 | 2021-12-16 | Buy |
Axon Medchem | Axon2517 | Napabucasin-BBI608|FNQ 99% | 50mg | $445.5 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546182 | Napabucasin >98% | 5mg | $168.3 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546182 | Napabucasin >98% | 25mg | $472.6 | 2021-12-16 | Buy |
Cayman Chemical | 22255 | Napabucasin ≥98% | 5mg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 22255 | Napabucasin ≥98% | 10mg | $116 | 2024-03-01 | Buy |
Cayman Chemical | 22255 | Napabucasin ≥98% | 25mg | $268 | 2024-03-01 | Buy |
Properties
Melting point :225-226℃ (dichloromethane )
Boiling point :444.4±45.0 °C(Predicted)
Density :1.385±0.06 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 20 mg/ml)
form :Brown solid
color :Yellow
λmax :272nm(EtOH)(lit.)
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Boiling point :444.4±45.0 °C(Predicted)
Density :1.385±0.06 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 20 mg/ml)
form :Brown solid
color :Yellow
λmax :272nm(EtOH)(lit.)
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Napabucasin is an inhibitor of cancer cell stemness. It reduces growth in a panel of cancer cells enriched for high stemness (IC50s = 0.291-1.249 μM) and decreases protein and gene expression of various self-renewal and pro-survival markers including Nanog, Smo, Axl, Atm, and Bmi-1 in a concentration-dependent manner in FaDu head and neck squamous cell carcinoma (HNSCC) cells. In vivo, napabucasin (20 mg/kg per day) inhibits tumor growth in a PaCa-2 mouse xenograft model and prevents tumor regrowth after cessation of treatment. It blocks formation of spleen and liver metastases in an HT29 intrasplenic nude mouse model system (ISMS) model. Napabucasin (40 mg/kg, i.p.) also reduces tumor volume in PC3 and 22RV1 prostate cancer mouse xenograft models.More related product prices
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Suppliers and manufacturers
Beijing Cooperate Pharmaceutical Co.,Ltd
Nanjing ChemLin Chemical Industry Co., Ltd.
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Biochempartner
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Alchem Pharmtech,Inc.
Shanxi Xuanran Import and Export Trade Co., Ltd.
Zhejiang J&C Biological Technology Co.,Limited