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ChemicalBook >> CAS DataBase List >> L-BUTHIONINE-(S,R)-SULFOXIMINE

L-BUTHIONINE-(S,R)-SULFOXIMINE

L-BUTHIONINE-(S,R)-SULFOXIMINE price.
  • $70 - $2333.1
  • Product name: L-BUTHIONINE-(S,R)-SULFOXIMINE
  • CAS: 83730-53-4
  • MF: C8H18N2O3S
  • MW: 222.31
  • EINECS:
  • MDL Number:MFCD00067000
  • Synonyms:L-BUTHIONINE-SULFOXIMINE;L-BUTHIONINE (R,S)-SULFOXIMINE;L-BUTHIONINE-[S,R]-SULFOXIME;L-BUTHIONINE-(S,R)-SULFOXIMINE;nsc326231 ;L-BUTHIONINESULPHOXIMINE;L-BUTHIONINE-S,R-SULPHOXIMINE;(2S)-2-Amino-4-(S-butylsulfonimidoyl)butanoic Acid
21 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Biosynth Carbosynth
  • Cayman Chemical
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 100mg
  • 500mg
  • 250mg
  • 100
  • 1G
  • 2g
  • 5g
  • 10G
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBIO0000090
  • Product descriptionL-BUTHIONINE-[S,R]-SULFOXIMINE 95.00%
  • Packaging1G
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberBIO0000090
  • Product descriptionL-BUTHIONINE-[S,R]-SULFOXIMINE 95.00%
  • Packaging10G
  • Price$2333.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19391
  • Product descriptionL-Buthionine-(S,R)-sulfoximine
  • Packaging100mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19391
  • Product descriptionL-Buthionine-(S,R)-sulfoximine
  • Packaging250mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19391
  • Product descriptionL-Buthionine-(S,R)-sulfoximine
  • Packaging500mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19391
  • Product descriptionL-Buthionine-(S,R)-sulfoximine
  • Packaging1g
  • Price$400
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB19391
  • Product descriptionL-Buthionine-(S,R)-sulfoximine
  • Packaging2g
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14484
  • Product descriptionButhionine Sulfoximine ≥98%
  • Packaging250mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14484
  • Product descriptionButhionine Sulfoximine ≥98%
  • Packaging500mg
  • Price$152
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14484
  • Product descriptionButhionine Sulfoximine ≥98%
  • Packaging1g
  • Price$286
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD21002232
  • Product description(2S)-2-Amino-4-(butylsulfonimidoyl)butanoicacid 95+%
  • Packaging10g
  • Price$1380
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD21002232
  • Product description(2S)-2-Amino-4-(butylsulfonimidoyl)butanoicacid 95+%
  • Packaging5g
  • Price$775
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number7919
  • Product descriptionL-Buthionine-(S,R)-sulfoximine
  • Packaging250mg
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number5.08228
  • Product descriptionL-ButhionineSulfoximine-CAS83730-53-4-Calbiochem
  • Packaging100mg
  • Price$142
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB2515
  • Product descriptionL-Buthionine-sulfoximine ≥97% (TLC)
  • Packaging500mg
  • Price$282
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB2515
  • Product descriptionL-Buthionine-sulfoximine ≥97% (TLC)
  • Packaging1g
  • Price$444
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation BIO0000090 L-BUTHIONINE-[S,R]-SULFOXIMINE 95.00% 1G $739.2 2021-12-16 Buy
American Custom Chemicals Corporation BIO0000090 L-BUTHIONINE-[S,R]-SULFOXIMINE 95.00% 10G $2333.1 2021-12-16 Buy
Biosynth Carbosynth FB19391 L-Buthionine-(S,R)-sulfoximine 100mg $80 2021-12-16 Buy
Biosynth Carbosynth FB19391 L-Buthionine-(S,R)-sulfoximine 250mg $150 2021-12-16 Buy
Biosynth Carbosynth FB19391 L-Buthionine-(S,R)-sulfoximine 500mg $250 2021-12-16 Buy
Biosynth Carbosynth FB19391 L-Buthionine-(S,R)-sulfoximine 1g $400 2021-12-16 Buy
Biosynth Carbosynth FB19391 L-Buthionine-(S,R)-sulfoximine 2g $700 2021-12-16 Buy
Cayman Chemical 14484 Buthionine Sulfoximine ≥98% 250mg $81 2024-03-01 Buy
Cayman Chemical 14484 Buthionine Sulfoximine ≥98% 500mg $152 2024-03-01 Buy
Cayman Chemical 14484 Buthionine Sulfoximine ≥98% 1g $286 2024-03-01 Buy
Crysdot CD21002232 (2S)-2-Amino-4-(butylsulfonimidoyl)butanoicacid 95+% 10g $1380 2021-12-16 Buy
Crysdot CD21002232 (2S)-2-Amino-4-(butylsulfonimidoyl)butanoicacid 95+% 5g $775 2021-12-16 Buy
Medical Isotopes, Inc. 7919 L-Buthionine-(S,R)-sulfoximine 250mg $290 2021-12-16 Buy
Sigma-Aldrich 5.08228 L-ButhionineSulfoximine-CAS83730-53-4-Calbiochem 100mg $142 2024-03-01 Buy
Sigma-Aldrich B2515 L-Buthionine-sulfoximine ≥97% (TLC) 500mg $282 2024-03-01 Buy
Sigma-Aldrich B2515 L-Buthionine-sulfoximine ≥97% (TLC) 1g $444 2024-03-01 Buy

Properties

Melting point :224-228 °C (dec.)
Boiling point :382.3±52.0 °C(Predicted)
Density :1.29
refractive index :1.6300 (estimate)
storage temp. :-20°C
solubility :H2O: 50 mg/mL, clear, colorless to faintly yellow
form :Fine Powder
color :White
BRN :2367136
Stability :Stable for 2 years from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily.
CAS DataBase Reference :83730-53-4

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Buthionine sulfoximine (BSO) is an irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM), the rate-limiting enzyme for L-glutathione (GSH) synthesis, that induces oxidative stress in cells by depleting GSH. Administration of BSO leads to decreased GSH levels in virtually all tissues and is associated with tissue damage and apoptosis. Whereas elevated glutathione levels are associated with tumor cell resistance, BSO has been shown to enhance the toxicity of various chemotherapeutic agents in drug-resistant tumors.

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