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ChemicalBook >> CAS DataBase List >> N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide

N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide

$50 - $2100
Product name: N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide
CAS: 839707-37-8
MF: C27H25F3N8O2
MW: 550.53
EINECS:804-647-7
MDL Number:MFCD20527253
Synonyms:SC1 (Pluripotin);N-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimid;N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide;Pluripotin;Pluripotin (SC-1);N-[3-[7-[(1,3-Dimethyl-1H-pyrazol-5-yl)amino]-1,4-dihydro-1-methyl-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide;N-[3-[7-(2,5-Dimethyl-2H-pyrazol-3-ylamino)-1-methyl-2-oxo-1,4-dihydro-2H-pyrimido[4,5-d]pyrimidin-3-yl]-4-methylphenyl]-3-trifluoromethyl-benzamide;CS-2160

Price35 Properties Safety Information Description

35 prices

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Brand

Ambeed
ApexBio Technology
Biosynth Carbosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Medical Isotopes, Inc.
Sigma-Aldrich
Tocris
TRC
Usbiological

Package

1
1mg
2mg
2.5mg
5mg
10mg
25mg
50mg
100mg
250mg
1g

ManufacturerAmbeed
Product numberA183088
Product descriptionN-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide 98+%
Packaging5mg
Price$168
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA183088
Product descriptionN-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide 98+%
Packaging10mg
Price$269
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA183088
Product descriptionN-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide 98+%
Packaging25mg
Price$431
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA183088
Product descriptionN-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide 98+%
Packaging50mg
Price$666
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB5593
Product descriptionPluripotin
Packaging2mg
Price$103
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB5593
Product descriptionPluripotin
Packaging50mg
Price$977
Updated2021-12-16
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ManufacturerApexBio Technology
Product numberB5593
Product descriptionPluripotin
Packaging100mg
Price$1260
Updated2021-12-16
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ManufacturerBiosynth Carbosynth
Product numberFP104266
Product descriptionPluripotin
Packaging10mg
Price$95
Updated2021-12-16
Buy

ManufacturerBiosynth Carbosynth
Product numberFP104266
Product descriptionPluripotin
Packaging50mg
Price$409
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number10009557
Product descriptionSC-1 ≥98%
Packaging1mg
Price$57
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number10009557
Product descriptionSC-1 ≥98%
Packaging5mg
Price$152
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number10009557
Product descriptionSC-1 ≥98%
Packaging10mg
Price$275
Updated2024-03-01
Buy

ManufacturerCayman Chemical
Product number10009557
Product descriptionSC-1 ≥98%
Packaging25mg
Price$601
Updated2024-03-01
Buy

ManufacturerChemScene
Product numberCS-5597
Product descriptionPluripotin 98.86%
Packaging2mg
Price$50
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-5597
Product descriptionPluripotin 98.86%
Packaging5mg
Price$70
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-5597
Product descriptionPluripotin 98.86%
Packaging10mg
Price$100
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Ambeed	A183088	N-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide 98+%	5mg	$168	2021-12-16	Buy
Ambeed	A183088	N-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide 98+%	10mg	$269	2021-12-16	Buy
Ambeed	A183088	N-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide 98+%	25mg	$431	2021-12-16	Buy
Ambeed	A183088	N-(3-(7-((1,3-Dimethyl-1H-pyrazol-5-yl)amino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide 98+%	50mg	$666	2021-12-16	Buy
ApexBio Technology	B5593	Pluripotin	2mg	$103	2021-12-16	Buy
ApexBio Technology	B5593	Pluripotin	50mg	$977	2021-12-16	Buy
ApexBio Technology	B5593	Pluripotin	100mg	$1260	2021-12-16	Buy
Biosynth Carbosynth	FP104266	Pluripotin	10mg	$95	2021-12-16	Buy
Biosynth Carbosynth	FP104266	Pluripotin	50mg	$409	2021-12-16	Buy
Cayman Chemical	10009557	SC-1 ≥98%	1mg	$57	2024-03-01	Buy
Cayman Chemical	10009557	SC-1 ≥98%	5mg	$152	2024-03-01	Buy
Cayman Chemical	10009557	SC-1 ≥98%	10mg	$275	2024-03-01	Buy
Cayman Chemical	10009557	SC-1 ≥98%	25mg	$601	2024-03-01	Buy
ChemScene	CS-5597	Pluripotin 98.86%	2mg	$50	2021-12-16	Buy
ChemScene	CS-5597	Pluripotin 98.86%	5mg	$70	2021-12-16	Buy
ChemScene	CS-5597	Pluripotin 98.86%	10mg	$100	2021-12-16	Buy

Next Last

Properties

Density :1.43
storage temp. :-20°C
solubility :DMSO: soluble10mg/mL (clear solution)
pka :12.82±0.70(Predicted)
form :powder
color :white to beige
InChIKey :NBZFRTJWEIHFPF-UHFFFAOYSA-N

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.

Description

SC1 is a small molecule shown to sustain self-renewal of mouse embryonic stem (mES) cells. In order to maintain embryonic stem cells in an undifferentiated state, it is typically necessary to use a combination of feeder cells, leukemia inhibitor factor (LIF) and bone morphogenic protein (BMP); SC1 (Pluripotin) allows for stem cell propagation in the absence of these factors. The activity of SC1 is mediated by Ras signaling which promotes self-renewal, and inhibition of ERK blocks differentiation.

Suppliers and manufacturers

career henan chemical co

$1.00 /1KG
N-(3-(7-(1,3-dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide CAS:839707-37-8

TargetMol Chemicals Inc.

$30.00 /1mg
Pluripotin CAS:839707-37-8

BOC Sciences

Zhejiang J&C Biological Technology Co.,Limited

InvivoChem

Hangzhou MolCore BioPharmatech Co.,Ltd.

TargetMol Chemicals Inc.

ShenZhen Trendseen Biological Technology Co.,Ltd.

Aladdin Scientific

Amadis Chemical Company Limited

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