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ChemicalBook >> CAS DataBase List >> (1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile

(1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile

(1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile price.
  • $40 - $4300
  • Product name: (1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile
  • CAS: 848344-36-5
  • MF: C25H23N5O2S
  • MW: 457.55
  • EINECS:604-604-1
  • MDL Number:
  • Synonyms:(1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile;AS 602801;Bentamapimod;AS 602801 (BentaMapiMod);(1,3-Benzothiazol-2-yl)[2-[[4-[(morpholin-4-yl)methyl]benzyl]oxy]pyrimidin-4-yl]acetonitrile AS602801(Bentamapimod);Bentamapimod (AS 602801);CS-401;2-(1,3-benzothiazol-2-yl)-2-[2-[[4-(morpholin-4-ylmethyl)phenyl]methoxy]pyrimidin-4-yl]acetonitrile
34 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Axon Medchem
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 2x25mg
  • 50mg
  • 100mg
  • 200mg
  • 10mM(in 1mL DMSO)
  • 500mg
  • 1g
  • 2g
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1147-M001
  • Product descriptionBentamapimod ≥95%
  • Packaging1mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN1147
  • Product descriptionBentamapimod
  • Packaging10mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3189
  • Product descriptionAS602801
  • Packaging10mM(in 1mL DMSO)
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3189
  • Product descriptionAS602801
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3189
  • Product descriptionAS602801
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3189
  • Product descriptionAS602801
  • Packaging200mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3189
  • Product descriptionAS602801
  • Packaging500mg
  • Price$1500
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2002
  • Product descriptionAS602801-Bentamapimod 98%
  • Packaging25mg
  • Price$231
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2002
  • Product descriptionAS602801-Bentamapimod 98%
  • Packaging2x25mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB146407
  • Product descriptionBentamapimod
  • Packaging1mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB146407
  • Product descriptionBentamapimod
  • Packaging2mg
  • Price$140
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB146407
  • Product descriptionBentamapimod
  • Packaging5mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB146407
  • Product descriptionBentamapimod
  • Packaging10mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB146407
  • Product descriptionBentamapimod
  • Packaging25mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21482
  • Product descriptionBentamapimod ≥98%
  • Packaging1mg
  • Price$40
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21482
  • Product descriptionBentamapimod ≥98%
  • Packaging5mg
  • Price$177
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences SYN-1147-M001 Bentamapimod ≥95% 1mg $205 2021-12-16 Buy
AK Scientific SYN1147 Bentamapimod 10mg $480 2021-12-16 Buy
ApexBio Technology A3189 AS602801 10mM(in 1mL DMSO) $77 2021-12-16 Buy
ApexBio Technology A3189 AS602801 10mg $120 2021-12-16 Buy
ApexBio Technology A3189 AS602801 50mg $250 2021-12-16 Buy
ApexBio Technology A3189 AS602801 200mg $800 2021-12-16 Buy
ApexBio Technology A3189 AS602801 500mg $1500 2021-12-16 Buy
Axon Medchem Axon2002 AS602801-Bentamapimod 98% 25mg $231 2021-12-16 Buy
Axon Medchem Axon2002 AS602801-Bentamapimod 98% 2x25mg $330 2021-12-16 Buy
Biosynth Carbosynth FB146407 Bentamapimod 1mg $80 2021-12-16 Buy
Biosynth Carbosynth FB146407 Bentamapimod 2mg $140 2021-12-16 Buy
Biosynth Carbosynth FB146407 Bentamapimod 5mg $300 2021-12-16 Buy
Biosynth Carbosynth FB146407 Bentamapimod 10mg $500 2021-12-16 Buy
Biosynth Carbosynth FB146407 Bentamapimod 25mg $1000 2021-12-16 Buy
Cayman Chemical 21482 Bentamapimod ≥98% 1mg $40 2024-03-01 Buy
Cayman Chemical 21482 Bentamapimod ≥98% 5mg $177 2024-03-01 Buy

Properties

Boiling point :666.5±65.0 °C(Predicted)
Density :1.326
storage temp. :2-8°C
solubility :insoluble in H2O; insoluble in EtOH; ≥11.45 mg/mL in DMSO
form :solid
pka :6.47±0.10(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Bentamapimod is an orally bioavailable inhibitor of Jun kinases (JNKs), with IC50 values for JNK1, JNK2, and JNK3 of 80, 90, and 230 nM, respectively. It is selective for JNKs over a panel of 25 related kinases. Bentamapimod induces regression of endometriotic lesions without suppressing estrogen action in animal models of endometriosis. It blocks proliferation and induces apoptosis of T cells in vitro and inhibits cancer stem cell survival, self-renewal, and tumor-initiating capacity in vitro and in mice.

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