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ChemicalBook >> CAS DataBase List >> 2-(14,15-EPOXYEICOSATRIENOYL) GLYCEROL

2-(14,15-EPOXYEICOSATRIENOYL) GLYCEROL

2-(14,15-EPOXYEICOSATRIENOYL) GLYCEROL price.
  • $185 - $844
  • Product name: 2-(14,15-EPOXYEICOSATRIENOYL) GLYCEROL
  • CAS: 848667-56-1
  • MF: C23H38O5
  • MW: 394.54
  • EINECS:
  • MDL Number:MFCD10567087
  • Synonyms:2-glyceryl 14,15-epoxy-(5Z,8Z,11Z)-icosatrienoate;2-14,15-EG;2-(14,15-EPOXYEICOSATRIENOYL) GLYCEROL;LPMVKZXODWQHGJ-ILYOTBPNSA-N;5,8,11-Tridecatrienoic acid, 13-(3-pentyl-2-oxiranyl)-, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (5Z,8Z,11Z)-
4 prices
Selected condition:
Brand
  • Cayman Chemical
  • TRC
Package
  • 25μg
  • 50μg
  • 100μg
  • 500μg
  • ManufacturerCayman Chemical
  • Product number10009962
  • Product description(±)2-(14,15-Epoxyeicosatrienoyl) Glycerol ≥95%
  • Packaging25μg
  • Price$235
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009962
  • Product description(±)2-(14,15-Epoxyeicosatrienoyl) Glycerol ≥95%
  • Packaging50μg
  • Price$447
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009962
  • Product description(±)2-(14,15-Epoxyeicosatrienoyl) Glycerol ≥95%
  • Packaging100μg
  • Price$844
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberE589135
  • Product description2-(14,15-Epoxyeicosatrienoyl)Glycerol
  • Packaging500μg
  • Price$185
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10009962 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol ≥95% 25μg $235 2024-03-01 Buy
Cayman Chemical 10009962 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol ≥95% 50μg $447 2024-03-01 Buy
Cayman Chemical 10009962 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol ≥95% 100μg $844 2024-03-01 Buy
TRC E589135 2-(14,15-Epoxyeicosatrienoyl)Glycerol 500μg $185 2021-12-16 Buy

Properties

Boiling point :531.5±50.0 °C(Predicted)
Density :1.038±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.15 mg/ml
pka :13.54±0.10(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

2-(14,15-Epoxyeicosatrienoyl) Glycerol (2-14,15-EG) is a novel CYP450 metabolite of 2-Arachidonoyl glycerol (2-AG) in the kidney. 2-14,15-EG is a potent mitogen for renal epithelial cells, increasing DNA synthesis in LLCPKcl4 cells at concentrations as low as 100 nM and doubling cell proliferation rates at 1 μM. In these cells, 2-14,15-EG activates the metalloprotease ADAM17 (TACE), which cleaves proTGF-α and releases TGF-α as a ligand that initiates the EGFR-ERK signalling pathway.

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