4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine
- $45 - $565
- Product name: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine
- CAS: 854847-61-3
- MF: C17H17NO2
- MW: 267.32
- EINECS:
- MDL Number:MFCD26961120
- Synonyms:4-Ethyl-5,6-Dihydro-5-methyl-[1,3]dioxolo[4,5-j]phenanthridine;4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine;HLY78;[1,3]Dioxolo[4,5-j]phenanthridine, 4-ethyl-5,6-dihydro-5-methyl-;HLY78 >=98% (HPLC);4-Ethyl-5-methyl-5;5-j]phenanthridine;Beta catenin,Neuronal apoptosis,HLY78,gastric cancer,SAH,subarachnoid hemorrhage,tumor cells,β-catenin,LRP6,inhibit,Inhibitor,anti-apoptotic,Blood-brain barrier,embryonic cells,Apoptosis,HLY-78,Wnt,HLY 78
12 prices
Selected condition:
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product numberSYN5048
- Product descriptionHLY78
- Packaging50mg
- Price$565
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5433
- Product descriptionHLY78
- Packaging5mg
- Price$112
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5433
- Product descriptionHLY78
- Packaging10mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5433
- Product descriptionHLY78
- Packaging25mg
- Price$437
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19087
- Product descriptionHLY78 ≥98%
- Packaging1mg
- Price$45
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19087
- Product descriptionHLY78 ≥98%
- Packaging5mg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19087
- Product descriptionHLY78 ≥98%
- Packaging10mg
- Price$177
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19087
- Product descriptionHLY78 ≥98%
- Packaging25mg
- Price$384
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0089730
- Product descriptionHLY78 98.38%
- Packaging5mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0089730
- Product descriptionHLY78 98.38%
- Packaging10mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0833
- Product descriptionHLY78 ≥98% (HPLC)
- Packaging5mg
- Price$94.3
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0833
- Product descriptionHLY78 ≥98% (HPLC)
- Packaging25mg
- Price$479
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5048 | HLY78 | 50mg | $565 | 2021-12-16 | Buy |
ApexBio Technology | C5433 | HLY78 | 5mg | $112 | 2021-12-16 | Buy |
ApexBio Technology | C5433 | HLY78 | 10mg | $200 | 2021-12-16 | Buy |
ApexBio Technology | C5433 | HLY78 | 25mg | $437 | 2021-12-16 | Buy |
Cayman Chemical | 19087 | HLY78 ≥98% | 1mg | $45 | 2024-03-01 | Buy |
Cayman Chemical | 19087 | HLY78 ≥98% | 5mg | $100 | 2024-03-01 | Buy |
Cayman Chemical | 19087 | HLY78 ≥98% | 10mg | $177 | 2024-03-01 | Buy |
Cayman Chemical | 19087 | HLY78 ≥98% | 25mg | $384 | 2024-03-01 | Buy |
ChemScene | CS-0089730 | HLY78 98.38% | 5mg | $160 | 2021-12-16 | Buy |
ChemScene | CS-0089730 | HLY78 98.38% | 10mg | $270 | 2021-12-16 | Buy |
Sigma-Aldrich | SML0833 | HLY78 ≥98% (HPLC) | 5mg | $94.3 | 2024-03-01 | Buy |
Sigma-Aldrich | SML0833 | HLY78 ≥98% (HPLC) | 25mg | $479 | 2024-03-01 | Buy |
Properties
Boiling point :444.0±34.0 °C(Predicted)
Density :1.208±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :4?+-.0.20(Predicted)
color :white to beige
Density :1.208±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :4?+-.0.20(Predicted)
color :white to beige
Safety Information
Symbol(GHS): | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | ||||||||||||||
Hazard statements: |
|
||||||||||||||
Precautionary statements: |
|
Description
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. HLY78 is a positive modulator of the Wnt/β-catenin pathway, as it augments Wnt-mediated signaling in cells at concentrations of 5 to 20 μM. It has no significant effect alone, and it does not affect LiCl-stimulated β-catenin signaling. A biotinylated form of HLY78 binds Axin at its DIX domain, which is thought to potentiate Axin-LRP6 association. HLY78 activates Wnt signaling in vivo, altering Wnt-dependent gene expression and embryonic development in zebrafish.Suppliers and manufacturers
Nantong HI-FUTURE Biology Co., Ltd.
Aladdin Scientific
Amadis Chemical Company Limited
ShangHai Caerulum Pharma Discovery Co., Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.
Pharmacodia (Beijing) Co.,Ltd
Shanghai EFE Biological Technology Co., Ltd.
ShangHai Biochempartner Co.,Ltd