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ChemicalBook >> CAS DataBase List >> 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine

4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine

4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine price.
  • $45 - $565
  • Product name: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine
  • CAS: 854847-61-3
  • MF: C17H17NO2
  • MW: 267.32
  • EINECS:
  • MDL Number:MFCD26961120
  • Synonyms:4-Ethyl-5,6-Dihydro-5-methyl-[1,3]dioxolo[4,5-j]phenanthridine;4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine;HLY78;[1,3]Dioxolo[4,5-j]phenanthridine, 4-ethyl-5,6-dihydro-5-methyl-;HLY78 >=98% (HPLC);4-Ethyl-5-methyl-5;5-j]phenanthridine;Beta catenin,Neuronal apoptosis,HLY78,gastric cancer,SAH,subarachnoid hemorrhage,tumor cells,β-catenin,LRP6,inhibit,Inhibitor,anti-apoptotic,Blood-brain barrier,embryonic cells,Apoptosis,HLY-78,Wnt,HLY 78
12 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product numberSYN5048
  • Product descriptionHLY78
  • Packaging50mg
  • Price$565
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5433
  • Product descriptionHLY78
  • Packaging5mg
  • Price$112
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5433
  • Product descriptionHLY78
  • Packaging10mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5433
  • Product descriptionHLY78
  • Packaging25mg
  • Price$437
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19087
  • Product descriptionHLY78 ≥98%
  • Packaging1mg
  • Price$45
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19087
  • Product descriptionHLY78 ≥98%
  • Packaging5mg
  • Price$100
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19087
  • Product descriptionHLY78 ≥98%
  • Packaging10mg
  • Price$177
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19087
  • Product descriptionHLY78 ≥98%
  • Packaging25mg
  • Price$384
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0089730
  • Product descriptionHLY78 98.38%
  • Packaging5mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0089730
  • Product descriptionHLY78 98.38%
  • Packaging10mg
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0833
  • Product descriptionHLY78 ≥98% (HPLC)
  • Packaging5mg
  • Price$94.3
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0833
  • Product descriptionHLY78 ≥98% (HPLC)
  • Packaging25mg
  • Price$479
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5048 HLY78 50mg $565 2021-12-16 Buy
ApexBio Technology C5433 HLY78 5mg $112 2021-12-16 Buy
ApexBio Technology C5433 HLY78 10mg $200 2021-12-16 Buy
ApexBio Technology C5433 HLY78 25mg $437 2021-12-16 Buy
Cayman Chemical 19087 HLY78 ≥98% 1mg $45 2024-03-01 Buy
Cayman Chemical 19087 HLY78 ≥98% 5mg $100 2024-03-01 Buy
Cayman Chemical 19087 HLY78 ≥98% 10mg $177 2024-03-01 Buy
Cayman Chemical 19087 HLY78 ≥98% 25mg $384 2024-03-01 Buy
ChemScene CS-0089730 HLY78 98.38% 5mg $160 2021-12-16 Buy
ChemScene CS-0089730 HLY78 98.38% 10mg $270 2021-12-16 Buy
Sigma-Aldrich SML0833 HLY78 ≥98% (HPLC) 5mg $94.3 2024-03-01 Buy
Sigma-Aldrich SML0833 HLY78 ≥98% (HPLC) 25mg $479 2024-03-01 Buy

Properties

Boiling point :444.0±34.0 °C(Predicted)
Density :1.208±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
form :powder
pka :4?+-.0.20(Predicted)
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H410 Very toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P273 Avoid release to the environment.
P501 Dispose of contents/container to..…

Description

Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. HLY78 is a positive modulator of the Wnt/β-catenin pathway, as it augments Wnt-mediated signaling in cells at concentrations of 5 to 20 μM. It has no significant effect alone, and it does not affect LiCl-stimulated β-catenin signaling. A biotinylated form of HLY78 binds Axin at its DIX domain, which is thought to potentiate Axin-LRP6 association. HLY78 activates Wnt signaling in vivo, altering Wnt-dependent gene expression and embryonic development in zebrafish.