S-(-)-7-Desmethyl-8-nitro Blebbistatin
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- $117 - $3000
- Product name: S-(-)-7-Desmethyl-8-nitro Blebbistatin
- CAS: 856925-75-2
- MF: C17H13N3O4
- MW: 323.3
- EINECS:
- MDL Number:MFCD17018077
- Synonyms:(3aS)-1,2,3,3a-Tetrahydro-3a-hydroxy-7-nitro-1-phenyl-4H-pyrrolo[2,3-β]quinolin-4-one;S-(-)-7-Desmethyl-8-nitro Blebbistatin;(3aS)-1,2,3,3a-Tetrahydro-3a-hydroxy-7-nitro-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one;(S)-nitro-Blebbistatin;4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-7-nitro-1-phenyl-, (3aS)-
12 prices
Selected condition：
Brand
- AK Scientific
- Biosynth Carbosynth
- Cayman Chemical
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 2mg
- 2.5mg
- 5mg
- 10mg
- 12.5mg
- 25mg
- ManufacturerAK Scientific
- Product number0257CT
- Product descriptionS-(-)-7-Desmethyl-8-nitroBlebbistatin
- Packaging5mg
- Price$613
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21357
- Product descriptionS-(-)-7-Desmethyl-8-nitro blebbistatin
- Packaging1mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21357
- Product descriptionS-(-)-7-Desmethyl-8-nitro blebbistatin
- Packaging2mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21357
- Product descriptionS-(-)-7-Desmethyl-8-nitro blebbistatin
- Packaging5mg
- Price$900
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21357
- Product descriptionS-(-)-7-Desmethyl-8-nitro blebbistatin
- Packaging10mg
- Price$1400
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD21357
- Product descriptionS-(-)-7-Desmethyl-8-nitro blebbistatin
- Packaging25mg
- Price$3000
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13891
- Product description(S)-nitro-Blebbistatin ≥98%
- Packaging1mg
- Price$117
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13891
- Product description(S)-nitro-Blebbistatin ≥98%
- Packaging5mg
- Price$463
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13891
- Product description(S)-nitro-Blebbistatin ≥98%
- Packaging10mg
- Price$727
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13891
- Product description(S)-nitro-Blebbistatin ≥98%
- Packaging25mg
- Price$1210
- Updated2024-03-01
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number9205
- Product descriptionS-(-)-7-Desmethyl-8-nitroBlebbistatin
- Packaging12.5mg
- Price$2120
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberD422350
- Product descriptionS-(-)-7-Desmethyl-8-nitroBlebbistatin
- Packaging2.5mg
- Price$145
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0257CT | S-(-)-7-Desmethyl-8-nitroBlebbistatin | 5mg | $613 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21357 | S-(-)-7-Desmethyl-8-nitro blebbistatin | 1mg | $280 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21357 | S-(-)-7-Desmethyl-8-nitro blebbistatin | 2mg | $480 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21357 | S-(-)-7-Desmethyl-8-nitro blebbistatin | 5mg | $900 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21357 | S-(-)-7-Desmethyl-8-nitro blebbistatin | 10mg | $1400 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21357 | S-(-)-7-Desmethyl-8-nitro blebbistatin | 25mg | $3000 | 2021-12-16 | Buy |
| Cayman Chemical | 13891 | (S)-nitro-Blebbistatin ≥98% | 1mg | $117 | 2024-03-01 | Buy |
| Cayman Chemical | 13891 | (S)-nitro-Blebbistatin ≥98% | 5mg | $463 | 2024-03-01 | Buy |
| Cayman Chemical | 13891 | (S)-nitro-Blebbistatin ≥98% | 10mg | $727 | 2024-03-01 | Buy |
| Cayman Chemical | 13891 | (S)-nitro-Blebbistatin ≥98% | 25mg | $1210 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | 9205 | S-(-)-7-Desmethyl-8-nitroBlebbistatin | 12.5mg | $2120 | 2021-12-16 | Buy |
| TRC | D422350 | S-(-)-7-Desmethyl-8-nitroBlebbistatin | 2.5mg | $145 | 2021-12-16 | Buy |
Properties
Boiling point :570.7±60.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 16 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :10.02±0.20(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 16 mg/ml; DMSO: 16 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form :A crystalline solid
pka :10.02±0.20(Predicted)
Safety Information
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Description
(+)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. By rapidly and reversibly inhibiting Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB, it blocks apoptosis-related bleb formation, directed cell migration and cytokinesis in vertebrate cells. However, prolonged exposure to blue light (450-490 nm) results in degradation of blebbistatin to an inactive product via cytotoxic intermediates, which may be problematic for its use in fluorescent live cell imaging applications. (S)-nitro-Blebbistatin is an analog of (?)-blebbistatin that is stable to prolonged irradiation at 450-490 nm. This compound, which has the same stereochemistry as the active (?)-blebbistatin isoform, has been successfully used in fluorescent live cell imaging.Suppliers and manufacturers
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