Leptomycin B
- $36 - $1190
- Product name: Leptomycin B
- CAS: 87081-35-4
- MF: C33H48O6
- MW: 540.73
- EINECS:617-954-4
- MDL Number:MFCD06795848
- Synonyms:(2E,10Z,12E,16Z,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxo-nonadeca-2,10,12,16,18-pentaenoic acid;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-;2,10,12,16,18-Nonadecapentanoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-;(2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-19-[(2S,3S)-3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl]-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-nonadecapentaenoicacid;LeptoMycin B( CI 940, LMB);antibioticcl1957a ;CI-940, Elactocin, PD 114720, ATS 1287B, Mantuamycin, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-Nonadecapentaenoic acid;Elactocin, ATS 1287B, CI 940, CL 1957A, PD 114720, MantuaMycin
17 prices
Selected condition:
Brand
- Alfa Aesar
- Apolloscientific
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 0.5μg
- 2x0.5μg
- 5x0.5μg
- 10x0.5μg
- 5μg
- 5ug
- 10μg
- 25μg
- 100μg
- 500ug
- 500μg
- 1mg
- 25g
- 100microg
- ManufacturerAlfa Aesar
- Product numberJ63784
- Product descriptionLeptomycin B, 99+%, 1mM soln. in ethanol
- Packaging100microg
- Price$276
- Updated2023-06-20
- Buy
- ManufacturerApolloscientific
- Product numberBIL2101
- Product descriptionLeptomycinB
- Packaging100μg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIL2101
- Product descriptionLeptomycinB
- Packaging500μg
- Price$508
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIL2101
- Product descriptionLeptomycinB
- Packaging1mg
- Price$907
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10004976
- Product descriptionLeptomycin B ≥98%
- Packaging5μg
- Price$36
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10004976
- Product descriptionLeptomycin B ≥98%
- Packaging10μg
- Price$61
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10004976
- Product descriptionLeptomycin B ≥98%
- Packaging25μg
- Price$120
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0012947
- Product descriptionLeptomycinB 99.71%
- Packaging5ug
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number74786
- Product descriptionLeptomycinB >99%
- Packaging500ug
- Price$1190
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number431050
- Product descriptionInSolution Leptomycin B, Streptomyces sp. - CAS 87081-35-4 - Calbiochem An antifungal antibiotic that acts as an inhibitor of nuclear export because of its ability to interact with and impair the function of the nuclear export factor CRM1.
- Packaging5μg
- Price$313.57
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number431050
- Product descriptionInSolution? Leptomycin B,
- Packaging5ug
- Price$327
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging5μg
- Price$399
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging10x0.5μg
- Price$367
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging5x0.5μg
- Price$234
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging2x0.5μg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberL2913
- Product descriptionLeptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3)
- Packaging0.5μg
- Price$57.7
- Updated2024-03-01
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Alfa Aesar | J63784 | Leptomycin B, 99+%, 1mM soln. in ethanol | 100microg | $276 | 2023-06-20 | Buy |
Apolloscientific | BIL2101 | LeptomycinB | 100μg | $138 | 2021-12-16 | Buy |
Apolloscientific | BIL2101 | LeptomycinB | 500μg | $508 | 2021-12-16 | Buy |
Apolloscientific | BIL2101 | LeptomycinB | 1mg | $907 | 2021-12-16 | Buy |
Cayman Chemical | 10004976 | Leptomycin B ≥98% | 5μg | $36 | 2024-03-01 | Buy |
Cayman Chemical | 10004976 | Leptomycin B ≥98% | 10μg | $61 | 2024-03-01 | Buy |
Cayman Chemical | 10004976 | Leptomycin B ≥98% | 25μg | $120 | 2024-03-01 | Buy |
ChemScene | CS-0012947 | LeptomycinB 99.71% | 5ug | $300 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 74786 | LeptomycinB >99% | 500ug | $1190 | 2021-12-16 | Buy |
Sigma-Aldrich | 431050 | InSolution Leptomycin B, Streptomyces sp. - CAS 87081-35-4 - Calbiochem An antifungal antibiotic that acts as an inhibitor of nuclear export because of its ability to interact with and impair the function of the nuclear export factor CRM1. | 5μg | $313.57 | 2021-12-16 | Buy |
Sigma-Aldrich | 431050 | InSolution? Leptomycin B, | 5ug | $327 | 2021-12-16 | Buy |
Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 5μg | $399 | 2024-03-01 | Buy |
Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 10x0.5μg | $367 | 2024-03-01 | Buy |
Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 5x0.5μg | $234 | 2024-03-01 | Buy |
Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 2x0.5μg | $107 | 2024-03-01 | Buy |
Sigma-Aldrich | L2913 | Leptomycin B solution from Streptomyces sp. ≥95% (HPLC), Supplied in methanol: water (7:3) | 0.5μg | $57.7 | 2024-03-01 | Buy |
Properties
Melting point :41-44°, with prior softening (Hokanson)
alpha :D -24.5° (c = 0.70 in MeOH); D23 -157 ° (c = 0.7% in chloroform)
Boiling point :725.8±60.0 °C(Predicted)
Density :1.072±0.06 g/cm3(Predicted)
Flash point :11°(52°F)
storage temp. :−20°C
solubility :Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO.
form :Liquid
pka :5.10±0.33(Predicted)
color :White to off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions or dilutions in DMSO are not stable. Solutions should be made fresh and used within one working day.
alpha :D -24.5° (c = 0.70 in MeOH); D23 -157 ° (c = 0.7% in chloroform)
Boiling point :725.8±60.0 °C(Predicted)
Density :1.072±0.06 g/cm3(Predicted)
Flash point :11°(52°F)
storage temp. :−20°C
solubility :Supplied in solution in ethanol (1 mg/ml). Further dilutions may be made with either ethanol or DMSO.
form :Liquid
pka :5.10±0.33(Predicted)
color :White to off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions or dilutions in DMSO are not stable. Solutions should be made fresh and used within one working day.
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Description
Potent, specific inhibitor of nuclear export signal (NES)-dependent protein export from the nucleusRelated product price
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