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ChemicalBook >> CAS DataBase List >> (±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-ethanone

(±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-ethanone

(±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-ethanone price.
  • $33 - $780
  • Product name: (±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-ethanone
  • CAS: 881639-98-1
  • MF: C21H18BrNO3
  • MW: 412.28
  • EINECS:
  • MDL Number:MFCD16618392
  • Synonyms:(±)-1-[(3aR*,4S*,9bS*)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-ethanone;1-((3aS,4R,9bR)-4-(6-bromobenzo[d][1,3]dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl)ethanone;G-06710-1;Ethanone, 1-[(3aR,4S,9bS)-4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl]-, rel-;1-((3aR,4S,9bS)-rel-4-(6-Bromobenzo[d][1,3]dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-8-yl)ethanone;G1,Inhibitor,G-1,inhibit,G 1,Estrogen Receptor/ERR
Price10 Properties Safety Information Description
10 prices
Selected condition：
Brand
  • Ambeed
  • ApexBio Technology
  • Cayman Chemical
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAmbeed
  • Product numberA287698
  • Product descriptionG-1 98+%
  • Packaging25mg
  • Price$206
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA287698
  • Product descriptionG-1 98+%
  • Packaging50mg
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA287698
  • Product descriptionG-1 98+%
  • Packaging100mg
  • Price$459
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA287698
  • Product descriptionG-1 98+%
  • Packaging250mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5455
  • Product descriptionG-1
  • Packaging10mg
  • Price$192
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008933
  • Product descriptionG-1 ≥98%
  • Packaging1mg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008933
  • Product descriptionG-1 ≥98%
  • Packaging5mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008933
  • Product descriptionG-1 ≥98%
  • Packaging10mg
  • Price$223
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008933
  • Product descriptionG-1 ≥98%
  • Packaging25mg
  • Price$475
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberG932035
  • Product descriptionG-1
  • Packaging5mg
  • Price$350
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A287698 G-1 98+% 25mg $206 2021-12-16 Buy
Ambeed A287698 G-1 98+% 50mg $310 2021-12-16 Buy
Ambeed A287698 G-1 98+% 100mg $459 2021-12-16 Buy
Ambeed A287698 G-1 98+% 250mg $780 2021-12-16 Buy
ApexBio Technology B5455 G-1 10mg $192 2021-12-16 Buy
Cayman Chemical 10008933 G-1 ≥98% 1mg $33 2024-03-01 Buy
Cayman Chemical 10008933 G-1 ≥98% 5mg $120 2024-03-01 Buy
Cayman Chemical 10008933 G-1 ≥98% 10mg $223 2024-03-01 Buy
Cayman Chemical 10008933 G-1 ≥98% 25mg $475 2024-03-01 Buy
TRC G932035 G-1 5mg $350 2021-12-16 Buy

Properties

Boiling point :529.6±50.0 °C(Predicted)
Density :1.457±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥41.2 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :crystalline solid
pka :1.20±0.40(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
H400 Very toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 1 Warning GHS hazard pictograms P273, P391, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

GPR30 is a transmembrane G protein-coupled receptor (GPCR) localized to endoplasmic reticulum (ER) that binds estradiol with high affinity, activating multiple intracellular signaling pathways. G-1 is a nonsteroidal, high-affinity, selective agonist of GPR30 that binds with a Ki value of 11 nM. Competitive binding studies in estrogen receptor α- (ERα-) and ERβ-expressing cells yielded Ki values for estradiol of 0.30 and 0.38 nM, respectively, with no substantial binding of G-1 at 1 μM. The discovery of G-1, a compound that does not bind classical ERs, should facilitate further physiological experiments to define the role of GPR30 in vivo.

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