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ChemicalBook >> CAS DataBase List >> 2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol

2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol

2-amino-2-[2-(3-azido-4-octylphenyl)ethyl]propane-1,3-diol price.
4 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 100μg
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerCayman Chemical
  • Product number10008612
  • Product descriptionazido-FTY720 ≥98%
  • Packaging100μg
  • Price$33
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008612
  • Product descriptionazido-FTY720 ≥98%
  • Packaging500μg
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008612
  • Product descriptionazido-FTY720 ≥98%
  • Packaging1mg
  • Price$254
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008612
  • Product descriptionazido-FTY720 ≥98%
  • Packaging5mg
  • Price$1105
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10008612 azido-FTY720 ≥98% 100μg $33 2024-03-01 Buy
Cayman Chemical 10008612 azido-FTY720 ≥98% 500μg $143 2024-03-01 Buy
Cayman Chemical 10008612 azido-FTY720 ≥98% 1mg $254 2024-03-01 Buy
Cayman Chemical 10008612 azido-FTY720 ≥98% 5mg $1105 2024-03-01 Buy

Properties

Melting point :63-65 °C
storage temp. :Store at -20°C
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2) (1:1): .2 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.1 FTY720 is phosphorylated by sphingosine kinase, which then acts as a potent agonist at four of the sphingosine-1-phosphate (S1P) receptors (S1P1, S1P3, S1P4, and S1P5).2 Down-regulation of S1P1 receptors on T and B lymphocytes by FTY720 results in defective egress of these cells from spleen, lymph nodes, and Peyer’s patch.3 azido-FTY720 is a highly photoreactive analog of FTY720 that can be used to identify receptor binding sites for this ligand.4