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ChemicalBook >> CAS DataBase List >> 2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide

2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide

2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide price.
  • $32 - $1800
  • Product name: 2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide
  • CAS: 883031-03-6
  • MF: C26H28F3N3O2
  • MW: 471.51
  • EINECS:
  • MDL Number:MFCD01571257
  • Synonyms:2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide;HC 067047;2-methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide;HC-067047;HC 067047;HC067047;1221277-90-2;1H-Pyrrole-3-carboxamide, 2-methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-;HC-067047 >=98% (HPLC);Transient receptor potential channels,HC-067047,Inhibitor,HC 067047,TRP Channel,inhibit
29 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 5mg
  • 10
  • 50
  • 1mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product number9976BA
  • Product description2-Methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7588
  • Product descriptionHC067047
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7588
  • Product descriptionHC067047
  • Packaging50mg
  • Price$430
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20927
  • Product descriptionHC-067047 ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20927
  • Product descriptionHC-067047 ≥98%
  • Packaging5mg
  • Price$70
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20927
  • Product descriptionHC-067047 ≥98%
  • Packaging10mg
  • Price$122
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20927
  • Product descriptionHC-067047 ≥98%
  • Packaging25mg
  • Price$267
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM255538
  • Product description2-Methyl-1-(3-morpholinopropyl)-5-phenyl-N-(3-(trifluoromethyl)phenyl)-1H-pyrrole-3-carboxamide 98%
  • Packaging100mg
  • Price$628
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5701
  • Product descriptionHC-067047 99.95%
  • Packaging5mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5701
  • Product descriptionHC-067047 99.95%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5701
  • Product descriptionHC-067047 99.95%
  • Packaging25mg
  • Price$264
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5701
  • Product descriptionHC-067047 99.95%
  • Packaging50mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5701
  • Product descriptionHC-067047 99.95%
  • Packaging100mg
  • Price$840
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000427
  • Product descriptionHC-067047 98+%
  • Packaging5mg
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000427
  • Product descriptionHC-067047 98+%
  • Packaging10mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000427
  • Product descriptionHC-067047 98+%
  • Packaging25mg
  • Price$166
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 9976BA 2-Methyl-1-(3-morpholin-4-ylpropyl)-5-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrole-3-carboxamide 1mg $133 2021-12-16 Buy
ApexBio Technology B7588 HC067047 10mg $110 2021-12-16 Buy
ApexBio Technology B7588 HC067047 50mg $430 2021-12-16 Buy
Cayman Chemical 20927 HC-067047 ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 20927 HC-067047 ≥98% 5mg $70 2024-03-01 Buy
Cayman Chemical 20927 HC-067047 ≥98% 10mg $122 2024-03-01 Buy
Cayman Chemical 20927 HC-067047 ≥98% 25mg $267 2024-03-01 Buy
Chemenu CM255538 2-Methyl-1-(3-morpholinopropyl)-5-phenyl-N-(3-(trifluoromethyl)phenyl)-1H-pyrrole-3-carboxamide 98% 100mg $628 2021-12-16 Buy
ChemScene CS-5701 HC-067047 99.95% 5mg $72 2021-12-16 Buy
ChemScene CS-5701 HC-067047 99.95% 10mg $120 2021-12-16 Buy
ChemScene CS-5701 HC-067047 99.95% 25mg $264 2021-12-16 Buy
ChemScene CS-5701 HC-067047 99.95% 50mg $480 2021-12-16 Buy
ChemScene CS-5701 HC-067047 99.95% 100mg $840 2021-12-16 Buy
Crysdot CD31000427 HC-067047 98+% 5mg $46 2021-12-16 Buy
Crysdot CD31000427 HC-067047 98+% 10mg $76 2021-12-16 Buy
Crysdot CD31000427 HC-067047 98+% 25mg $166 2021-12-16 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: ≥15mg/mL
form :powder
color :white to tan
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

HC-067047 (883031-03-6) is a potent reversible and selective TRPV4 blocker. Active at mouse, human and rat TRPV4, IC50?= 17, 48 and 133 nM respectively. Also inhibits the endogenous TRPV4-mediated response to 4α-PDH (IC50 = 22 nM). Selective for TRPV4 over TRPV1, TRPV2, TRPV3 and TRPM8 channels.1 Increases functional bladder capacity and reduces micturition frequency in mice and rats with cystitis.1 Inhibits brain edema in middle cerebral artery occlusion mice.2 HC-067047 induces an increase in core body temperature accompanied by increased oxygen consumption in Wistar rats.3?Active?in vivo.

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