N-(2-(2-(4-chlorophenyl)thiazol-4-yl)ethyl)butyraMide
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- $44 - $1400
- Product name: N-(2-(2-(4-chlorophenyl)thiazol-4-yl)ethyl)butyraMide
- CAS: 932986-18-0
- MF: C15H17ClN2OS
- MW: 308.83
- EINECS:
- MDL Number:MFCD08009374
- Synonyms:Azoramide;N-(2-(2-(4-chlorophenyl)thiazol-4-yl)ethyl)butyraMide;N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide;Azoraminde;CS-1554;N-[2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl]butanamide;Butanamide, N-[2-[2-(4-chlorophenyl)-4-thiazolyl]ethyl]-
20 prices
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Brand
- Abosyn
- AK Scientific
- Ark Pharm
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAbosyn
- Product number61-11524
- Product descriptionN-(2-(2-(4-Chlorophenyl)thiazol-4-yl)ethyl)butyramide 95-98%
- Packaging1g
- Price$980
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8564CQ
- Product descriptionN-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide
- Packaging10mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000105065
- Product descriptionAzoramide 98+%
- Packaging1mg
- Price$63
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000105065
- Product descriptionAzoramide 98+%
- Packaging5mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000105065
- Product descriptionAzoramide 98+%
- Packaging10mg
- Price$141
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000105065
- Product descriptionAzoramide 98+%
- Packaging50mg
- Price$532
- Updated2021-12-16
- Buy
- ManufacturerArk Pharm
- Product numberP000105065
- Product descriptionAzoramide 98+%
- Packaging100mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546239
- Product descriptionAzoramide >98%
- Packaging10mg
- Price$154.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546239
- Product descriptionAzoramide >98%
- Packaging50mg
- Price$348.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18045
- Product descriptionAzoramide ≥98%
- Packaging5mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18045
- Product descriptionAzoramide ≥98%
- Packaging10mg
- Price$84
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18045
- Product descriptionAzoramide ≥98%
- Packaging25mg
- Price$193
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18045
- Product descriptionAzoramide ≥98%
- Packaging50mg
- Price$341
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM190376
- Product descriptionN-(2-(2-(4-chlorophenyl)thiazol-4-yl)ethyl)butyramide 98%
- Packaging100mg
- Price$413
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11010582
- Product descriptionAzoramide 98+%
- Packaging50mg
- Price$374
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11010582
- Product descriptionAzoramide 98+%
- Packaging100mg
- Price$660
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
Abosyn | 61-11524 | N-(2-(2-(4-Chlorophenyl)thiazol-4-yl)ethyl)butyramide 95-98% | 1g | $980 | 2021-12-16 | Buy |
AK Scientific | 8564CQ | N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide | 10mg | $190 | 2021-12-16 | Buy |
Ark Pharm | P000105065 | Azoramide 98+% | 1mg | $63 | 2021-12-16 | Buy |
Ark Pharm | P000105065 | Azoramide 98+% | 5mg | $86 | 2021-12-16 | Buy |
Ark Pharm | P000105065 | Azoramide 98+% | 10mg | $141 | 2021-12-16 | Buy |
Ark Pharm | P000105065 | Azoramide 98+% | 50mg | $532 | 2021-12-16 | Buy |
Ark Pharm | P000105065 | Azoramide 98+% | 100mg | $750 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546239 | Azoramide >98% | 10mg | $154.7 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546239 | Azoramide >98% | 50mg | $348.5 | 2021-12-16 | Buy |
Cayman Chemical | 18045 | Azoramide ≥98% | 5mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 18045 | Azoramide ≥98% | 10mg | $84 | 2024-03-01 | Buy |
Cayman Chemical | 18045 | Azoramide ≥98% | 25mg | $193 | 2024-03-01 | Buy |
Cayman Chemical | 18045 | Azoramide ≥98% | 50mg | $341 | 2024-03-01 | Buy |
Chemenu | CM190376 | N-(2-(2-(4-chlorophenyl)thiazol-4-yl)ethyl)butyramide 98% | 100mg | $413 | 2021-12-16 | Buy |
Crysdot | CD11010582 | Azoramide 98+% | 50mg | $374 | 2021-12-16 | Buy |
Crysdot | CD11010582 | Azoramide 98+% | 100mg | $660 | 2021-12-16 | Buy |
Properties
Melting point :90-93°C
Density :1.215
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in ethanol (up to at least 25 mg/ml)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Density :1.215
storage temp. :-20°C
solubility :Soluble in DMSO (up to at least 25 mg/ml) or in ethanol (up to at least 25 mg/ml)
form :solid
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
Safety Information
Symbol(GHS): |
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Description
The unfolded protein response (UPR) maintains balance between protein synthesis and endoplasmic reticulum (ER) protein-folding by inhibiting translation to decrease global protein synthesis, increasing degradation and disposal of unfolded protein intermediates from the ER, and increasing the folding capacity of the ER by expanding its volume and increasing chaperone synthesis. Chronic ER stress leads to a defective UPR and is strongly associated with neurodegenerative diseases, cancers, and metabolic syndrome. Azoramide is a small molecule that has been shown to improve ER protein-folding ability by dose-dependently (1-25 μM) activating reporter genes whose expression is driven by the cellular UPR response element and the ER stress response element. At 1-25 μM, this compound can also stimulate the expression of multiple chaperone proteins to enhance ER chaperone capacity and induce phosphorylation of eukaryotic translation initiation factor 2α subunit (eIF2α) to reduce protein synthesis. At 150 mg/kg, azoramide exerts antidiabetic activity in both ob/ob and diet-induced obese mice, improving insulin sensitivity and glucose homeostasis, as well as protecting pancreatic β cells against ER stress.More related product prices
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