Casein Kinase II Inhibitor III
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- $37 - $1380
- Product name: Casein Kinase II Inhibitor III
- CAS: 934358-00-6
- MF: C9H4Br4O2
- MW: 463.74
- EINECS:-0
- MDL Number:MFCD20921901
- Synonyms:InSolution? Casein Kinase II Inhibitor III, TBCA ;Casein Kinase II Inhibitor III;(E)-3-(2,3,4,5-Tetrabromophenyl)acrylic Acid;TBCA;Tetrabromocinnamic acid;Casein Kinase II Inhibitor III, TBCA;SVJQCVOKYJWUBC-OWOJBTEDSA-N;(2E)-3-(2,3,4,5-Tetrabromophenyl)-2-propenoic acid
16 prices
Selected condition：
Brand
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 1mg
- 10
- 10μg
- 5mg
- 10mg
- 25mg
- 100mg
- ManufacturerApexBio Technology
- Product numberC3957
- Product descriptionTBCA
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3957
- Product descriptionTBCA
- Packaging10mg
- Price$242
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3957
- Product descriptionTBCA
- Packaging25mg
- Price$553
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb598048
- Product descriptionTBCA
- Packaging10μg
- Price$290.7
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14831
- Product descriptionTBCA ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14831
- Product descriptionTBCA ≥98%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14831
- Product descriptionTBCA ≥98%
- Packaging10mg
- Price$213
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14831
- Product descriptionTBCA ≥98%
- Packaging25mg
- Price$485
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0032876
- Product descriptionTBCA ≥98.0%
- Packaging5mg
- Price$285
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number61933
- Product description(E)-3-(2,3,4,5-Tetrabromophenyl)acrylicAcid
- Packaging100mg
- Price$1380
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0854
- Product descriptionTBCA ≥98% (HPLC)
- Packaging5mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number218710
- Product descriptionCasein Kinase II Inhibitor III, TBCA
- Packaging5mg
- Price$201
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number218861
- Product descriptionInSolution? Casein Kinase II Inhibitor III, TBCA
- Packaging5mg
- Price$216
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML0854
- Product descriptionTBCA ≥98% (HPLC)
- Packaging25mg
- Price$589
- Updated2023-01-07
- Buy
- ManufacturerTocris
- Product number2825
- Product descriptionTBCA ≥98%(HPLC)
- Packaging10
- Price$199
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberT291160
- Product description(E)-3-(2,3,4,5-Tetrabromophenyl)acrylicAcid
- Packaging10mg
- Price$115
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ApexBio Technology | C3957 | TBCA | 5mg | $130 | 2021-12-16 | Buy |
| ApexBio Technology | C3957 | TBCA | 10mg | $242 | 2021-12-16 | Buy |
| ApexBio Technology | C3957 | TBCA | 25mg | $553 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb598048 | TBCA | 10μg | $290.7 | 2021-12-16 | Buy |
| Cayman Chemical | 14831 | TBCA ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 14831 | TBCA ≥98% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 14831 | TBCA ≥98% | 10mg | $213 | 2024-03-01 | Buy |
| Cayman Chemical | 14831 | TBCA ≥98% | 25mg | $485 | 2024-03-01 | Buy |
| ChemScene | CS-0032876 | TBCA ≥98.0% | 5mg | $285 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 61933 | (E)-3-(2,3,4,5-Tetrabromophenyl)acrylicAcid | 100mg | $1380 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML0854 | TBCA ≥98% (HPLC) | 5mg | $152 | 2024-03-01 | Buy |
| Sigma-Aldrich | 218710 | Casein Kinase II Inhibitor III, TBCA | 5mg | $201 | 2024-03-01 | Buy |
| Sigma-Aldrich | 218861 | InSolution? Casein Kinase II Inhibitor III, TBCA | 5mg | $216 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0854 | TBCA ≥98% (HPLC) | 25mg | $589 | 2023-01-07 | Buy |
| Tocris | 2825 | TBCA ≥98%(HPLC) | 10 | $199 | 2021-12-16 | Buy |
| TRC | T291160 | (E)-3-(2,3,4,5-Tetrabromophenyl)acrylicAcid | 10mg | $115 | 2021-12-16 | Buy |
Properties
Melting point :189.2-191.2 °C
Boiling point :490.8±45.0 °C(Predicted)
Density :2.443±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :3.83±0.16(Predicted)
form :powder
color :white to beige
Boiling point :490.8±45.0 °C(Predicted)
Density :2.443±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :3.83±0.16(Predicted)
form :powder
color :white to beige
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Casein kinase 2 (CK2) is a kinase with many targets and diverse roles in cell signaling and disease. TBCA is a selective, cell-permeable inhibitor of CK2 (IC50 = 0.11 μM, Ki = 77 nM) that has minimal effect on a panel of 28 other kinases. It induces cell death in Jurkat adult T cell leukemia cells (DC50 = 7.7 μM), driving caspase-dependent degradation of poly-ADP ribose polymerase while inhibiting CK2 activity. TBCA also supports a role for CK2 in platelet function and Akt phosphorylation but not protein splicing.Suppliers and manufacturers
Wuhan Topule Biopharmaceutical Co., Ltd
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Beijing Jin Ming Biotechnology Co., Ltd.
Shenzhen Polymeri Biochemical Technology Co., Ltd.
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Guangzhou Younan Technology Co., Ltd
MedBioPharmaceutical Technology Inc
Jinan Jiuli Biotechnology Co. , Ltd.