[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide, Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl]-
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide, Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl]- price.](/CAS/GIF/945526-43-2.gif)
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- $34 - $1700
- Product name: [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide, Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl]-
- CAS: 945526-43-2
- MF: C19H21N3O2S
- MW: 355.45
- EINECS:
- MDL Number:MFCD12031591
- Synonyms:[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide, Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl]-;ISCK03;SteM-Cell Factor/c-Kit Inhibitor, ISCK03;[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide;Benzenesulfonamide,4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl];ISCK 03; ISCK-03;4-tert-butyl-N-(4-imidazol-1-ylphenyl)benzenesulfonamide;Stem-Cell Factor/c-Kit Inhibitor, ISCK03 - CAS 945526-43-2 - Calbiochem
31 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 1MG
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number1455BB
- Product descriptionTert-Butylphenylimidazolylphenylsulfonamide
- Packaging100mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65114
- Product descriptionStem-Cell Factor/c-Kit Inhibitor
- Packaging10mg
- Price$139
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65114
- Product descriptionStem-Cell Factor/c-Kit Inhibitor
- Packaging50mg
- Price$459
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA263965
- Product descriptionISCK03 98+%
- Packaging5mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA263965
- Product descriptionISCK03 98+%
- Packaging10mg
- Price$273
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA263965
- Product descriptionISCK03 98+%
- Packaging25mg
- Price$354
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA263965
- Product descriptionISCK03 98+%
- Packaging50mg
- Price$460
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA263965
- Product descriptionISCK03 98+%
- Packaging100mg
- Price$598
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000313
- Product description[4-T-BUTYLPHENYL]-N-(4-IMIDAZOL-1-YL PHENYL)SULFONAMIDE 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000313
- Product description[4-T-BUTYLPHENYL]-N-(4-IMIDAZOL-1-YL PHENYL)SULFONAMIDE 95.00%
- Packaging5MG
- Price$670.32
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000313
- Product description[4-T-BUTYLPHENYL]-N-(4-IMIDAZOL-1-YL PHENYL)SULFONAMIDE 95.00%
- Packaging25MG
- Price$922.3
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3152
- Product descriptionISCK03
- Packaging25mg
- Price$422
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15781
- Product descriptionISCK03 ≥95%
- Packaging1mg
- Price$34
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15781
- Product descriptionISCK03 ≥95%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15781
- Product descriptionISCK03 ≥95%
- Packaging10mg
- Price$166
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15781
- Product descriptionISCK03 ≥95%
- Packaging25mg
- Price$371
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1455BB | Tert-Butylphenylimidazolylphenylsulfonamide | 100mg | $180 | 2021-12-16 | Buy |
| Alfa Aesar | J65114 | Stem-Cell Factor/c-Kit Inhibitor | 10mg | $139 | 2023-06-20 | Buy |
| Alfa Aesar | J65114 | Stem-Cell Factor/c-Kit Inhibitor | 50mg | $459 | 2021-12-16 | Buy |
| Ambeed | A263965 | ISCK03 98+% | 5mg | $210 | 2021-12-16 | Buy |
| Ambeed | A263965 | ISCK03 98+% | 10mg | $273 | 2021-12-16 | Buy |
| Ambeed | A263965 | ISCK03 98+% | 25mg | $354 | 2021-12-16 | Buy |
| Ambeed | A263965 | ISCK03 98+% | 50mg | $460 | 2021-12-16 | Buy |
| Ambeed | A263965 | ISCK03 98+% | 100mg | $598 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000313 | [4-T-BUTYLPHENYL]-N-(4-IMIDAZOL-1-YL PHENYL)SULFONAMIDE 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000313 | [4-T-BUTYLPHENYL]-N-(4-IMIDAZOL-1-YL PHENYL)SULFONAMIDE 95.00% | 5MG | $670.32 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000313 | [4-T-BUTYLPHENYL]-N-(4-IMIDAZOL-1-YL PHENYL)SULFONAMIDE 95.00% | 25MG | $922.3 | 2021-12-16 | Buy |
| ApexBio Technology | C3152 | ISCK03 | 25mg | $422 | 2021-12-16 | Buy |
| Cayman Chemical | 15781 | ISCK03 ≥95% | 1mg | $34 | 2024-03-01 | Buy |
| Cayman Chemical | 15781 | ISCK03 ≥95% | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 15781 | ISCK03 ≥95% | 10mg | $166 | 2024-03-01 | Buy |
| Cayman Chemical | 15781 | ISCK03 ≥95% | 25mg | $371 | 2024-03-01 | Buy |
Properties
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in ethanol or DMSO
form :solid
color :yellow
Sensitive :Light Sensitive
InChIKey :XQABBHBFHWHMKF-UHFFFAOYSA-N
solubility :Soluble in ethanol or DMSO
form :solid
color :yellow
Sensitive :Light Sensitive
InChIKey :XQABBHBFHWHMKF-UHFFFAOYSA-N
Safety Information
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Description
The receptor tyrosine kinase c-kit, activated by its ligand stem-cell factor (SCF), modulates diverse cellular processes, including cell proliferation, differentiation, and survival. ISCK03 is a cell-permeable inhibitor of SCF-mediated c-kit activation, completely blocking phosphorylation of c-kit in human melanoma cells at a concentration between 1 and 5 μM. These concentrations also prevent SCF-mediated downstream phosphorylation of p44/p42 ERK but does not prevent phosphorylation of p44/p42 ERK induced by hepatocyte growth factor. Oral administration of ISCK03 in mice induces hair depigmentation, whereas topical application decreases epidermal melanin in guinea pig skin darkened by UV irradiation. ISCK03 has also been used to elucidate the role of SCF/c-kit signaling in cell viability, radiation-induced angiogenesis, and melanocortin receptor action.More related product prices
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![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide, Benzenesulfonamide, 4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl]-](https://img.chemicalbook.com/ProductImageEN/2019-12/small/1113a923-acfb-4d03-ac9d-6927d4fc7f9a.jpg){kind=small}