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ChemicalBook >> CAS DataBase List >> 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine

4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine

4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine price.
  • $37 - $1732.5
  • Product name: 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine
  • CAS: 956025-83-5
  • MF: C17H21N5
  • MW: 295.38
  • EINECS:
  • MDL Number:MFCD11655904
  • Synonyms:1-(1,1-Dimethylethyl)-3-[(3-methylphenyl)methyl]-1H-Pyrazolo[3,4-d]pyrimidin-4- amine;3-MB-PP1;4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine;1-tert-butyl-3-(3-Methylbenzyl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;4-Amino-1-tert-butyl-(3-methylbenzyl)pyrazolo[3,4-D]pyrimidine;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-[(3-methylphenyl)methyl]-;PP1 Analog III, 3-MB-PP1 - CAS 956025-83-5 - Calbiochem;1-tert-butyl-3-[(3-methylphenyl)methyl]pyrazolo[3,4-d]pyrimidin-4-amine
Price15 Properties Safety Information Description
15 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 1MG
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • ManufacturerAK Scientific
  • Product number1827DC
  • Product description1-Tert-Butyl-3-(3-Methylbenzyl)-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine
  • Packaging10mg
  • Price$334
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002450
  • Product description4-AMINO-1-TERT-BUTYL-3-(3-METHYLBENZYL)PYRAZOLO(3,4-D)PYRIMIDINE 95.00%
  • Packaging1MG
  • Price$140.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002450
  • Product description4-AMINO-1-TERT-BUTYL-3-(3-METHYLBENZYL)PYRAZOLO(3,4-D)PYRIMIDINE 95.00%
  • Packaging10MG
  • Price$721.88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0002450
  • Product description4-AMINO-1-TERT-BUTYL-3-(3-METHYLBENZYL)PYRAZOLO(3,4-D)PYRIMIDINE 95.00%
  • Packaging100MG
  • Price$1732.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3340
  • Product description3MB-PP1
  • Packaging5mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3340
  • Product description3MB-PP1
  • Packaging10mg
  • Price$242
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA15230
  • Product description4-Amino-1-tert-butyl-(3-methylbenzyl)pyrazolo[3,4-D]pyrimidine
  • Packaging2mg
  • Price$86
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA15230
  • Product description4-Amino-1-tert-butyl-(3-methylbenzyl)pyrazolo[3,4-D]pyrimidine
  • Packaging25mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA15230
  • Product description4-Amino-1-tert-butyl-(3-methylbenzyl)pyrazolo[3,4-D]pyrimidine
  • Packaging50mg
  • Price$988
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17860
  • Product description3MB-PP1 ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17860
  • Product description3MB-PP1 ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17860
  • Product description3MB-PP1 ≥98%
  • Packaging10mg
  • Price$213
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number6408
  • Product description4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine
  • Packaging10mg
  • Price$860
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number529582
  • Product descriptionPP1 Analog III, 3-MB-PP1 - CAS 956025-83-5 - Calbiochem
  • Packaging5mg
  • Price$159
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberA602960
  • Product description4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine
  • Packaging2mg
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1827DC 1-Tert-Butyl-3-(3-Methylbenzyl)-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine 10mg $334 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002450 4-AMINO-1-TERT-BUTYL-3-(3-METHYLBENZYL)PYRAZOLO(3,4-D)PYRIMIDINE 95.00% 1MG $140.7 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002450 4-AMINO-1-TERT-BUTYL-3-(3-METHYLBENZYL)PYRAZOLO(3,4-D)PYRIMIDINE 95.00% 10MG $721.88 2021-12-16 Buy
American Custom Chemicals Corporation KIN0002450 4-AMINO-1-TERT-BUTYL-3-(3-METHYLBENZYL)PYRAZOLO(3,4-D)PYRIMIDINE 95.00% 100MG $1732.5 2021-12-16 Buy
ApexBio Technology C3340 3MB-PP1 5mg $130 2021-12-16 Buy
ApexBio Technology C3340 3MB-PP1 10mg $242 2021-12-16 Buy
Biosynth Carbosynth FA15230 4-Amino-1-tert-butyl-(3-methylbenzyl)pyrazolo[3,4-D]pyrimidine 2mg $86 2021-12-16 Buy
Biosynth Carbosynth FA15230 4-Amino-1-tert-butyl-(3-methylbenzyl)pyrazolo[3,4-D]pyrimidine 25mg $550 2021-12-16 Buy
Biosynth Carbosynth FA15230 4-Amino-1-tert-butyl-(3-methylbenzyl)pyrazolo[3,4-D]pyrimidine 50mg $988 2021-12-16 Buy
Cayman Chemical 17860 3MB-PP1 ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 17860 3MB-PP1 ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 17860 3MB-PP1 ≥98% 10mg $213 2024-03-01 Buy
Medical Isotopes, Inc. 6408 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine 10mg $860 2021-12-16 Buy
Sigma-Aldrich 529582 PP1 Analog III, 3-MB-PP1 - CAS 956025-83-5 - Calbiochem 5mg $159 2024-03-01 Buy
TRC A602960 4-Amino-1-tert-butyl-3-(3-methylbenzyl)pyrazolo[3,4-d]pyrimidine 2mg $100 2021-12-16 Buy

Properties

Melting point :136-1380C
Boiling point :475.5±40.0 °C(Predicted)
Density :1.20±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), Methanol (Slightly)
form :White solid
pka :4.52±0.30(Predicted)
color :White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

In several model organisms, the generation of conditional analog-sensitive kinase alleles has been developed as a chemical genetic strategy wherein a mutational enlargement of the ATP-binding site enables a protein kinase to interact with bulky ATP analogs. Thus, a generic bulky ATP analog can competitively inhibit the activity of the mutant kinase, without interfering with the function of wild-type kinases whose ATP-binding pockets remain too small to accommodate the bulky analog. 3MB-PP1 is a bulky purine analog that acts as a selective, ATP-competitive, analog-sensitive polo-like kinase 1 (Plk1) allele inhibitor. At 10 μM, it can block mitotic progression in cells expressing analog-sensitive Plk1 alleles and has been used to selectively sensitize Plk1 to small-molecule inhibitors.

Suppliers and manufacturers

CONIER CHEM AND PHARMA LIMITED
LEAPCHEM CO., LTD.
Aladdin Scientific
Amadis Chemical Company Limited J & K SCIENTIFIC LTD. Chemsky（shanghai）International Co.,Ltd. BOC Sciences Shanghai T&W Pharmaceutical Co., Ltd. Sigma-Aldrich Shanghai EFE Biological Technology Co., Ltd.