ABT-639
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- $44 - $2520
- Product name: ABT-639
- CAS: 1235560-28-7
- MF: C20H20ClF2N3O3S
- MW: 455.91
- EINECS:
- MDL Number:MFCD29924737
- Synonyms:ABT-639;4-Chloro-2-fluoro-N-(2-fluorophenyl)-5-[[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl]carbonyl]benzenesulfonamide;4-CHLORO-2-FLURO-N-(2-FLUOROPHENYL)-5-[(8AR)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-2(1H)-YLCARBONYL]BENZENESULFONAMIDE;ABT-639, CID 46851313;(R)-4-chloro-2-fluoro-N-(2-fluorophenyl)-5-(octahydropyrrolo[1,2-a]pyrazine-2-carbonyl)benzenesulfonamide;ABT-639 (ABT639;CS-2286;ABT-693
17 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Tocris
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number8455DG
- Product descriptionAbt-639
- Packaging5mg
- Price$289
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number28742
- Product descriptionABT-639
- Packaging1mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28742
- Product descriptionABT-639
- Packaging5mg
- Price$172
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28742
- Product descriptionABT-639
- Packaging10mg
- Price$257
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number28742
- Product descriptionABT-639
- Packaging25mg
- Price$586
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5515
- Product descriptionABT-639 99.36%
- Packaging1mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5515
- Product descriptionABT-639 99.36%
- Packaging5mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5515
- Product descriptionABT-639 99.36%
- Packaging10mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5515
- Product descriptionABT-639 99.36%
- Packaging50mg
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5515
- Product descriptionABT-639 99.36%
- Packaging100mg
- Price$2520
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004143
- Product descriptionABT-639 98+%
- Packaging5mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004143
- Product descriptionABT-639 98+%
- Packaging10mg
- Price$347
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004143
- Product descriptionABT-639 98+%
- Packaging50mg
- Price$1042
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004143
- Product descriptionABT-639 98+%
- Packaging100mg
- Price$1459
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9706
- Product descriptionABT-639 >98%
- Packaging100mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9706
- Product descriptionABT-639 >98%
- Packaging250mg
- Price$1200
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 8455DG | Abt-639 | 5mg | $289 | 2021-12-16 | Buy |
Cayman Chemical | 28742 | ABT-639 | 1mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 28742 | ABT-639 | 5mg | $172 | 2024-03-01 | Buy |
Cayman Chemical | 28742 | ABT-639 | 10mg | $257 | 2024-03-01 | Buy |
Cayman Chemical | 28742 | ABT-639 | 25mg | $586 | 2024-03-01 | Buy |
ChemScene | CS-5515 | ABT-639 99.36% | 1mg | $180 | 2021-12-16 | Buy |
ChemScene | CS-5515 | ABT-639 99.36% | 5mg | $420 | 2021-12-16 | Buy |
ChemScene | CS-5515 | ABT-639 99.36% | 10mg | $600 | 2021-12-16 | Buy |
ChemScene | CS-5515 | ABT-639 99.36% | 50mg | $1800 | 2021-12-16 | Buy |
ChemScene | CS-5515 | ABT-639 99.36% | 100mg | $2520 | 2021-12-16 | Buy |
Crysdot | CD31004143 | ABT-639 98+% | 5mg | $243 | 2021-12-16 | Buy |
Crysdot | CD31004143 | ABT-639 98+% | 10mg | $347 | 2021-12-16 | Buy |
Crysdot | CD31004143 | ABT-639 98+% | 50mg | $1042 | 2021-12-16 | Buy |
Crysdot | CD31004143 | ABT-639 98+% | 100mg | $1459 | 2021-12-16 | Buy |
DC Chemicals | DC9706 | ABT-639 >98% | 100mg | $650 | 2021-12-16 | Buy |
DC Chemicals | DC9706 | ABT-639 >98% | 250mg | $1200 | 2021-12-16 | Buy |
Properties
Boiling point :612.2±65.0 °C(Predicted)
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:9.71(Max Conc. mg/mL);21.3(Max Conc. mM)
DMF:14.0(Max Conc. mg/mL);30.71(Max Conc. mM)
DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.09(Max Conc. mM)
Ethanol:0.5(Max Conc. mg/mL);1.1(Max Conc. mM) form :A solid
pka :6.80±0.10(Predicted)
color :White to off-white
Density :1.51±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:9.71(Max Conc. mg/mL);21.3(Max Conc. mM)
DMF:14.0(Max Conc. mg/mL);30.71(Max Conc. mM)
DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.09(Max Conc. mM)
Ethanol:0.5(Max Conc. mg/mL);1.1(Max Conc. mM) form :A solid
pka :6.80±0.10(Predicted)
color :White to off-white
Safety Information
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Description
ABT-639 is a T-type calcium channel blocker. It inhibits inactivated-state Cav3.2 channels with an IC50 value of 2.3 μM and inactivated-state Cav3.1 and Cav3.3 channels by 50 and 39%, respectively, when used at a concentration of 10 μM. ABT-639 selectively inhibits inactivated-state T-type calcium currents over resting-state currents in rat dorsal root ganglion (DRG) neurons (IC50s = 7.6 and >30 μM, respectively). It reverses the hind limb grip force deficit in a rat model of osteoarthritic pain induced by monoiodoacetic acid (MIA; ED50 = 2 mg/kg). ABT-639 also increases the paw withdrawal threshold in rat spinal nerve ligation (SNL) and chronic constriction injury (CCI) models of neuropathic pain in a dose-dependent manner and attenuates cold allodynia in the CCI rat model when administered at doses greater than or equal to 3 mg/kg.More related product prices
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$1.00 /1KG
4-Chloro-2-fluoro-N-(2-fluorophenyl)-5-[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-ylcarbonyl]benzenesulfonamide CAS:1235560-28-7
4-Chloro-2-fluoro-N-(2-fluorophenyl)-5-[(8aR)-hexahydropyrrolo[1,2-a]pyrazin-2(1H)-ylcarbonyl]benzenesulfonamide CAS:1235560-28-7