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ChemicalBook >> CAS DataBase List >> AMG 925

AMG 925

AMG 925 price.
  • $32 - $2237
  • Product name: AMG 925
  • CAS: 1401033-86-0
  • MF: C26H29N7O2
  • MW: 471.55
  • EINECS:
  • MDL Number:MFCD28155269
  • Synonyms:AMG 925;1-[7,8-Dihydro-2-[[9-(trans-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl]amino]-1,6-naphthyridin-6(5H)-yl]-2-hydroxyethanone;2-Hydroxy-1-(2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-;Ethanone, 1-[7,8-dihydro-2-[[9-(trans-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl]amino]-1,6-naphthyridin-6(5H)-yl]-2-hydroxy-;AMG 925;AMG925;AMG-925;CS-1594;2-Hydroxy-1-(2-((9-((1r,4r)-4-methylcyclohexyl)-9H-pyrido[4',3':4,5]pyrrolo[2,3-d]pyrimidin-2-yl)amino)-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)ethanone;AMG925; AMG-925; AMG 925; FLX925; FLX-925; FLX 925.
Price27 Properties Safety Information Description
27 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5735
  • Product descriptionAMG-925
  • Packaging100mg
  • Price$2237
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3277
  • Product descriptionAMG925
  • Packaging5mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3277
  • Product descriptionAMG925
  • Packaging25mg
  • Price$335
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3277
  • Product descriptionAMG925
  • Packaging100mg
  • Price$685
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA137647
  • Product descriptionAMG 925
  • Packaging10mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA137647
  • Product descriptionAMG 925
  • Packaging50mg
  • Price$507.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number29245
  • Product descriptionAMG 925
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29245
  • Product descriptionAMG 925
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29245
  • Product descriptionAMG 925
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number29245
  • Product descriptionAMG 925
  • Packaging25mg
  • Price$267
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2486
  • Product descriptionAMG925 98.24%
  • Packaging5mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2486
  • Product descriptionAMG925 98.24%
  • Packaging10mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2486
  • Product descriptionAMG925 98.24%
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2486
  • Product descriptionAMG925 98.24%
  • Packaging100mg
  • Price$550
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003624
  • Product descriptionAMG925 98+%
  • Packaging5mg
  • Price$84
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003624
  • Product descriptionAMG925 98+%
  • Packaging10mg
  • Price$133
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5735 AMG-925 100mg $2237 2021-12-16 Buy
ApexBio Technology B3277 AMG925 5mg $105 2021-12-16 Buy
ApexBio Technology B3277 AMG925 25mg $335 2021-12-16 Buy
ApexBio Technology B3277 AMG925 100mg $685 2021-12-16 Buy
Biosynth Carbosynth FA137647 AMG 925 10mg $145 2021-12-16 Buy
Biosynth Carbosynth FA137647 AMG 925 50mg $507.5 2021-12-16 Buy
Cayman Chemical 29245 AMG 925 1mg $32 2024-03-01 Buy
Cayman Chemical 29245 AMG 925 5mg $93 2024-03-01 Buy
Cayman Chemical 29245 AMG 925 10mg $153 2024-03-01 Buy
Cayman Chemical 29245 AMG 925 25mg $267 2024-03-01 Buy
ChemScene CS-2486 AMG925 98.24% 5mg $85 2021-12-16 Buy
ChemScene CS-2486 AMG925 98.24% 10mg $120 2021-12-16 Buy
ChemScene CS-2486 AMG925 98.24% 50mg $350 2021-12-16 Buy
ChemScene CS-2486 AMG925 98.24% 100mg $550 2021-12-16 Buy
Crysdot CD31003624 AMG925 98+% 5mg $84 2021-12-16 Buy
Crysdot CD31003624 AMG925 98+% 10mg $133 2021-12-16 Buy
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Properties

Boiling point :712.3±70.0 °C(Predicted)
Density :1.48±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :13.41±0.10(Predicted)
color :Light yellow to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

AMG 925 is a dual inhibitor of FMS-related tyrosine kinase 3 (FLT3) and cyclin-dependent kinase 4 (Cdk4; IC50s = 1 and 3 nM, respectively). It is selective for FLT3 and Cdk4 over Cdk1 (IC50 = 2.22 μM). AMG 925 also binds to FLT3ITD, FLT3D835Y, FLT3D835H, FLT3K663Q, and FLT3N841I (Kds = 1-4 nM). It inhibits proliferation of MOLM-13, COLO 205, and U937 cancer cells (IC50s = 19, 55, and 52 nM, respectively). AMG 925 (50, 75, and 150 mg/kg) reduces intratumor levels of pSTAT5 and pRb and inhibits tumor growth in a MOLM-13 acute myeloid leukemia (AML) mouse xenograft model.

Suppliers and manufacturers

BOC Sciences
InvivoChem
TargetMol Chemicals Inc.
Aladdin Scientific
Amadis Chemical Company Limited WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. Dalian Meilun Biotech Co., Ltd. Shanghai Topbiochem Technology Co., Ltd Haoyuan Chemexpress Co., Ltd. AdooQ BioScience, LLC