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ChemicalBook >> CAS DataBase List >> AMG 9810

AMG 9810

AMG 9810 price.
  • $34 - $1350
  • Product name: AMG 9810
  • CAS: 545395-94-6
  • MF: C21H23NO3
  • MW: 337.41
  • EINECS:
  • MDL Number:MFCD00955103
  • Synonyms:3-[4-(TERT-BUTYL)PHENYL]-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ACRYLAMIDE;AMG 9810;(2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE;(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide;2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)-;CS-2548;AMG 9810;AMG-9810;3-(4-tert-Butyl-phenyl)-N-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-acrylamide
32 prices
Selected condition:
Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • ApexBio Technology
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mg
  • 50
  • 5mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 10
  • 1g
  • ManufacturerAHH
  • Product numberMT-09667
  • Product description(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide 98%
  • Packaging1g
  • Price$488
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8773BA
  • Product description(E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide
  • Packaging50mg
  • Price$279
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64202
  • Product descriptionAMG 9810
  • Packaging25mg
  • Price$308
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA715034
  • Product descriptionAMG 9810 98%
  • Packaging5mg
  • Price$34
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA715034
  • Product descriptionAMG 9810 98%
  • Packaging10mg
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA715034
  • Product descriptionAMG 9810 98%
  • Packaging50mg
  • Price$78
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA715034
  • Product descriptionAMG 9810 98%
  • Packaging100mg
  • Price$124
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA715034
  • Product descriptionAMG 9810 98%
  • Packaging250mg
  • Price$249
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA715034
  • Product descriptionAMG 9810 98%
  • Packaging1g
  • Price$620
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7018
  • Product descriptionAMG 9810
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7018
  • Product descriptionAMG 9810
  • Packaging25mg
  • Price$155
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7018
  • Product descriptionAMG 9810
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA164880
  • Product descriptionAMG 9810
  • Packaging10mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA164880
  • Product descriptionAMG 9810
  • Packaging50mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA164880
  • Product descriptionAMG 9810
  • Packaging100mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFA164880
  • Product descriptionAMG 9810
  • Packaging250mg
  • Price$500
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-09667 (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propenamide 98% 1g $488 2021-12-16 Buy
AK Scientific 8773BA (E)-3-(4-t-Butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide 50mg $279 2021-12-16 Buy
Alfa Aesar J64202 AMG 9810 25mg $308 2023-06-20 Buy
Ambeed A715034 AMG 9810 98% 5mg $34 2021-12-16 Buy
Ambeed A715034 AMG 9810 98% 10mg $44 2021-12-16 Buy
Ambeed A715034 AMG 9810 98% 50mg $78 2021-12-16 Buy
Ambeed A715034 AMG 9810 98% 100mg $124 2021-12-16 Buy
Ambeed A715034 AMG 9810 98% 250mg $249 2021-12-16 Buy
Ambeed A715034 AMG 9810 98% 1g $620 2021-12-16 Buy
ApexBio Technology B7018 AMG 9810 10mg $70 2021-12-16 Buy
ApexBio Technology B7018 AMG 9810 25mg $155 2021-12-16 Buy
ApexBio Technology B7018 AMG 9810 50mg $300 2021-12-16 Buy
Biosynth Carbosynth FA164880 AMG 9810 10mg $60 2021-12-16 Buy
Biosynth Carbosynth FA164880 AMG 9810 50mg $170 2021-12-16 Buy
Biosynth Carbosynth FA164880 AMG 9810 100mg $260 2021-12-16 Buy
Biosynth Carbosynth FA164880 AMG 9810 250mg $500 2021-12-16 Buy

Properties

Boiling point :512.5±50.0 °C(Predicted)
Density :1.175±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5mg/mL
pka :12.22±0.20(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H413 May cause long lasting harmful effects to aquatic life Hazardous to the aquatic environment, long-term hazard Category 4
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501 Dispose of contents/container to..…

Description

AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat, respectively). Additionally, it has been shown to compete with other modes of TRPV1 activation, including protons (IC50s = 92.7 and 294 nM for human and rat, respectively), heat (IC50s = 15.8 and 21 nM for human and rat, respectively), and the endogenous ligands: anandamide, N-arachidonyl dopamine (IC50s = 8.5 and 260 nM for human and rat, respectively), and oleoyldopamine. In a rat model of inflammatory pain induced by intraplantar injection of complete Freund’s adjuvant, 30-100 mg/kg AMG 9810 reverses thermal and mechanical hyperalgesia.

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