ANSAMITOCIN P-3
- $50 - $1200
- Product name: ANSAMITOCIN P-3
- CAS: 66547-09-9
- MF: C32H43ClN2O9
- MW: 635.14
- EINECS:
- MDL Number:MFCD01939731
- Synonyms:3-de(2-(acetylmethylamino)propionyloxy)-3-hydroxy-maytansinbutyrate(ester ;Maytansine, 3-de(2-(acetylmethylamino)propionyloxy)-3-hydroxy-, butyrate (ester);Maytansine, o(sup 3)-de(2-(acetylmethylamino)-1-oxopropyl)-o(sup 3)-(1-oxobutyl)- (9ci);Ansamitocin P-3, >=70%;Maytansinoid AP-3;ANSAMITOCIN P-N;Aansamitocin P3;3-de(2-(acetylmethylamino)propionyloxy)-3-hydroxymaytansinebutyrate(ester)
26 prices
Selected condition:
Brand
- ApexBio Technology
- BroadPharm
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 250mg
- 1g
- 10mM(in 1mL DMSO)
- 50mg
- 100mg
- ManufacturerApexBio Technology
- Product numberA3183
- Product descriptionAnsamitocinP-3
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3183
- Product descriptionAnsamitocinP-3
- Packaging10mM(in 1mL DMSO)
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3183
- Product descriptionAnsamitocinP-3
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3183
- Product descriptionAnsamitocinP-3
- Packaging25mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3183
- Product descriptionAnsamitocinP-3
- Packaging50mg
- Price$490
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-23646
- Product descriptionMaytansinoidAP-3 95%
- Packaging25mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-23646
- Product descriptionMaytansinoidAP-3 95%
- Packaging50mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerBroadPharm
- Product numberBP-23646
- Product descriptionMaytansinoidAP-3 95%
- Packaging100mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number20538
- Product descriptionAnsamitocin P-3 ≥85%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20538
- Product descriptionAnsamitocin P-3 ≥85%
- Packaging5mg
- Price$169
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20538
- Product descriptionAnsamitocin P-3 ≥85%
- Packaging10mg
- Price$302
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20538
- Product descriptionAnsamitocin P-3 ≥85%
- Packaging25mg
- Price$669
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5466
- Product descriptionAnsamitocinP3'
- Packaging2mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5466
- Product descriptionAnsamitocinP3'
- Packaging5mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5466
- Product descriptionAnsamitocinP3'
- Packaging10mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5466
- Product descriptionAnsamitocinP3'
- Packaging25mg
- Price$300
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
ApexBio Technology | A3183 | AnsamitocinP-3 | 5mg | $90 | 2021-12-16 | Buy |
ApexBio Technology | A3183 | AnsamitocinP-3 | 10mM(in 1mL DMSO) | $120 | 2021-12-16 | Buy |
ApexBio Technology | A3183 | AnsamitocinP-3 | 10mg | $150 | 2021-12-16 | Buy |
ApexBio Technology | A3183 | AnsamitocinP-3 | 25mg | $300 | 2021-12-16 | Buy |
ApexBio Technology | A3183 | AnsamitocinP-3 | 50mg | $490 | 2021-12-16 | Buy |
BroadPharm | BP-23646 | MaytansinoidAP-3 95% | 25mg | $180 | 2021-12-16 | Buy |
BroadPharm | BP-23646 | MaytansinoidAP-3 95% | 50mg | $290 | 2021-12-16 | Buy |
BroadPharm | BP-23646 | MaytansinoidAP-3 95% | 100mg | $420 | 2021-12-16 | Buy |
Cayman Chemical | 20538 | Ansamitocin P-3 ≥85% | 1mg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 20538 | Ansamitocin P-3 ≥85% | 5mg | $169 | 2024-03-01 | Buy |
Cayman Chemical | 20538 | Ansamitocin P-3 ≥85% | 10mg | $302 | 2024-03-01 | Buy |
Cayman Chemical | 20538 | Ansamitocin P-3 ≥85% | 25mg | $669 | 2024-03-01 | Buy |
ChemScene | CS-5466 | AnsamitocinP3' | 2mg | $50 | 2021-12-16 | Buy |
ChemScene | CS-5466 | AnsamitocinP3' | 5mg | $90 | 2021-12-16 | Buy |
ChemScene | CS-5466 | AnsamitocinP3' | 10mg | $150 | 2021-12-16 | Buy |
ChemScene | CS-5466 | AnsamitocinP3' | 25mg | $300 | 2021-12-16 | Buy |
Properties
Melting point :182-185℃
Boiling point :837.6±65.0 °C(Predicted)
Density :1.30±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 30 mg/ml with warming).
pka :9.83±0.70(Predicted)
form :White to off-white crystalline solid.
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Boiling point :837.6±65.0 °C(Predicted)
Density :1.30±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 50 mg/ml) or in Ethanol (up to 30 mg/ml with warming).
pka :9.83±0.70(Predicted)
form :White to off-white crystalline solid.
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
Safety Information
Symbol(GHS): | |||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | ||||||||||||||||||||||||||||||||||||||||||
Hazard statements: |
|
||||||||||||||||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Ansamitocin P-3 is a microtubule depolymerizing agent that can be isolated from culture broths of certain Gram-positive bacteria. It binds tubulin (Kd = 1.3 μM), depolymerizes microtubules in both interphase and mitosis, and perturbs chromosome segregation. Ansamitocin P-3 also activates the spindle checkpoint surveillance proteins Mad2 and BubR1, blocking cell cycling during mitosis. It inhibits the growth of cancer cells in culture and significantly suppresses the growth of several cancer tumors in mice, prolonging survival time.Related product price
- MYOSEVERIN
$36-795.33 - NOCODAZOLE
$36-1504.5 - ansamitocin P-3
$41-5040