AP26113
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- $28 - $1169
- Product name: AP26113
- CAS: 1197958-12-5
- MF: C26H34ClN6O2P
- MW: 529.01
- EINECS:234-394-2
- MDL Number:MFCD23704187
- Synonyms:5-chloro-2-N-[4-[4-(dimethylamino)piperidin-1-yl]-2-methoxyphenyl]-4-N-(2-dimethylphosphorylphenyl)pyrimidine-2,4-diamine;AP26113-ANALOG;(2-((5-Chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)ami;AP26113;AP26113/AP-26113;5-chloro-N2-(4-(4-(diMethylaMino)piperidin-1-yl)-2-Methoxy-5-Methylphenyl)-N4-(2-(diMethylphosphoryl)phenyl)pyriMidine-2,4-diaMine;5-Chloro-N2-[4-[4-(dimethylamino)-1-piperidinyl]-2-methoxyphenyl]-N4-[2-(dimethylphosphinyl)phenyl]-2,4-pyrimidinediamine;5-Chloro-N2-[4-[4-(diMethylaMino)-1-piperidinyl]-2-Methoxyphenyl]-N4-[2-(diMethylphosphinyl)phenyl]
29 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
- Usbiological
Package
- 1mg
- 25mg
- 100mg
- 250mg
- 1g
- 1unit
- 5MG
- 10mg
- 50mg
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product number2218AH
- Product description(2-((5-Chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide
- Packaging10mg
- Price$151
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2218AH
- Product description(2-((5-Chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide
- Packaging50mg
- Price$404
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0026216
- Product descriptionAP-26113 95.00%
- Packaging5MG
- Price$499.71
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1367
- Product descriptionAP26113
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1367
- Product descriptionAP26113
- Packaging5mg
- Price$84
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1367
- Product descriptionAP26113
- Packaging10mM(in 1mL DMSO)
- Price$93
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1367
- Product descriptionAP26113
- Packaging10mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1367
- Product descriptionAP26113
- Packaging50mg
- Price$333
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA1367
- Product descriptionAP26113
- Packaging100mg
- Price$428
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD76641
- Product descriptionAP 26113
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD76641
- Product descriptionAP 26113
- Packaging50mg
- Price$262.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18775
- Product descriptionALK-IN-1 ≥98%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18775
- Product descriptionALK-IN-1 ≥98%
- Packaging5mg
- Price$201
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18775
- Product descriptionALK-IN-1 ≥98%
- Packaging10mg
- Price$370
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18775
- Product descriptionALK-IN-1 ≥98%
- Packaging50mg
- Price$1169
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM166858
- Product description(2-((5-Chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98%
- Packaging100mg
- Price$252
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 2218AH | (2-((5-Chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide | 10mg | $151 | 2021-12-16 | Buy |
AK Scientific | 2218AH | (2-((5-Chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide | 50mg | $404 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0026216 | AP-26113 95.00% | 5MG | $499.71 | 2021-12-16 | Buy |
ApexBio Technology | A1367 | AP26113 | 1unit | $28 | 2021-12-16 | Buy |
ApexBio Technology | A1367 | AP26113 | 5mg | $84 | 2021-12-16 | Buy |
ApexBio Technology | A1367 | AP26113 | 10mM(in 1mL DMSO) | $93 | 2021-12-16 | Buy |
ApexBio Technology | A1367 | AP26113 | 10mg | $147 | 2021-12-16 | Buy |
ApexBio Technology | A1367 | AP26113 | 50mg | $333 | 2021-12-16 | Buy |
ApexBio Technology | A1367 | AP26113 | 100mg | $428 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD76641 | AP 26113 | 10mg | $75 | 2021-12-16 | Buy |
Biosynth Carbosynth | FD76641 | AP 26113 | 50mg | $262.5 | 2021-12-16 | Buy |
Cayman Chemical | 18775 | ALK-IN-1 ≥98% | 1mg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 18775 | ALK-IN-1 ≥98% | 5mg | $201 | 2024-03-01 | Buy |
Cayman Chemical | 18775 | ALK-IN-1 ≥98% | 10mg | $370 | 2024-03-01 | Buy |
Cayman Chemical | 18775 | ALK-IN-1 ≥98% | 50mg | $1169 | 2024-03-01 | Buy |
Chemenu | CM166858 | (2-((5-Chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphineoxide 98% | 100mg | $252 | 2021-12-16 | Buy |
Properties
Boiling point :737.6±70.0 °C(Predicted)
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥26.45 mg/mL in DMSO; insoluble in H2O; ≥55.9 mg/mL in EtOH
form :solid
pka :9.27±0.20(Predicted)
color :White to off-white
CAS DataBase Reference :1197958-12-5
Density :1.29±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥26.45 mg/mL in DMSO; insoluble in H2O; ≥55.9 mg/mL in EtOH
form :solid
pka :9.27±0.20(Predicted)
color :White to off-white
CAS DataBase Reference :1197958-12-5
Safety Information
Symbol(GHS): |
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Description
ALK-IN-1 is an analog of AP26113, a phosphine oxide-containing ALK inhibitor. ALK-IN-1 potently inhibits ALK (IC50 = 0.07 nM) over IGF-1R and InsR (IC50s = 3.2 and 100 nM, respectively). It drives cell death in (ALK+) Karpas-299 lymphoma cells with an IC50 value of 41.5 nM, while killing (ALK-) U937 cells with an IC50 value of 1,718 nM.Related product price
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Suppliers and manufacturers
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