ARV-771
|
- $57 - $4173.5
- Product name: ARV-771
- CAS: 1949837-12-0
- MF: C49H60ClN9O7S2
- MW: 986.65
- EINECS:
- MDL Number:MFCD30738017
- Synonyms:ARV-771;ARV 771; ARV771;(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide;(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-;(2S,4R)-1-((2S)-2-(tert-butyl)-15-((6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,14-dioxo-6,10-dioxa-3,13-diazapentadecan-1-oyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide;Epigenetic Reader Domain,ARV-771,ARV771,inhibit,ARV 771,PROTACs,Inhibitor
18 prices
Selected condition：
Brand
- AK Scientific
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- Tocris
Package
- 1mg
- 5mg
- 50mg
- 5
- 10mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number2258EJ
- Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-Chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide
- Packaging10mg
- Price$768
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573102
- Product descriptionARV-771 >98%
- Packaging100mg
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573102
- Product descriptionARV-771 >98%
- Packaging250mg
- Price$2097.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573102
- Product descriptionARV-771 >98%
- Packaging1g
- Price$4173.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21299
- Product descriptionARV-771
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21299
- Product descriptionARV-771
- Packaging5mg
- Price$141
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21299
- Product descriptionARV-771
- Packaging10mg
- Price$253
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM328356
- Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+
- Packaging10mg
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM328356
- Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+
- Packaging50mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM328356
- Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+
- Packaging100mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM328356
- Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+
- Packaging250mg
- Price$780
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6389
- Product descriptionARV-771 99.82%
- Packaging1mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6389
- Product descriptionARV-771 99.82%
- Packaging5mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6389
- Product descriptionARV-771 99.82%
- Packaging10mg
- Price$600
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6389
- Product descriptionARV-771 99.82%
- Packaging50mg
- Price$1800
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-6389
- Product descriptionARV-771 99.82%
- Packaging100mg
- Price$2520
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 2258EJ | (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-Chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide | 10mg | $768 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573102 | ARV-771 >98% | 100mg | $1208.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573102 | ARV-771 >98% | 250mg | $2097.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573102 | ARV-771 >98% | 1g | $4173.5 | 2021-12-16 | Buy |
| Cayman Chemical | 21299 | ARV-771 | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 21299 | ARV-771 | 5mg | $141 | 2024-03-01 | Buy |
| Cayman Chemical | 21299 | ARV-771 | 10mg | $253 | 2024-03-01 | Buy |
| Chemenu | CM328356 | (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+ | 10mg | $178 | 2021-12-16 | Buy |
| Chemenu | CM328356 | (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+ | 50mg | $300 | 2021-12-16 | Buy |
| Chemenu | CM328356 | (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+ | 100mg | $390 | 2021-12-16 | Buy |
| Chemenu | CM328356 | (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+ | 250mg | $780 | 2021-12-16 | Buy |
| ChemScene | CS-6389 | ARV-771 99.82% | 1mg | $180 | 2021-12-16 | Buy |
| ChemScene | CS-6389 | ARV-771 99.82% | 5mg | $420 | 2021-12-16 | Buy |
| ChemScene | CS-6389 | ARV-771 99.82% | 10mg | $600 | 2021-12-16 | Buy |
| ChemScene | CS-6389 | ARV-771 99.82% | 50mg | $1800 | 2021-12-16 | Buy |
| ChemScene | CS-6389 | ARV-771 99.82% | 100mg | $2520 | 2021-12-16 | Buy |
Properties
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:65.92(Max Conc. mg/mL);68.22(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);20.7(Max Conc. mM)
DMF:PBS (pH 7.2) (1:6):0.14(Max Conc. mg/mL);0.14(Max Conc. mM)
Ethanol:55.0(Max Conc. mg/mL);56.92(Max Conc. mM) form :A crystalline solid
pka :13.61±0.46(Predicted)
color :White to light yellow
InChIKey :PQOGZKGXGLHDGS-BZTQNJCZNA-N
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:65.92(Max Conc. mg/mL);68.22(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);20.7(Max Conc. mM)
DMF:PBS (pH 7.2) (1:6):0.14(Max Conc. mg/mL);0.14(Max Conc. mM)
Ethanol:55.0(Max Conc. mg/mL);56.92(Max Conc. mM) form :A crystalline solid
pka :13.61±0.46(Predicted)
color :White to light yellow
InChIKey :PQOGZKGXGLHDGS-BZTQNJCZNA-N
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
ARV-771 is a BET PROTAC based on E3 ligase von Hippel-Lindau with Kds of 34 nM, 4.7 nM, 8.3 nM, 7.6 nM, 9.6 nM, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1) and BRD4(2), respectively.Suppliers and manufacturers
Shanghai finete Pharmaceutical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Zhengzhou Alfa Chemical Co.,Ltd
Career Henan Chemica Co
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
