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ChemicalBook >> CAS DataBase List >> ARV-771

ARV-771

ARV-771 price.
  • $57 - $4173.5
  • Product name: ARV-771
  • CAS: 1949837-12-0
  • MF: C49H60ClN9O7S2
  • MW: 986.65
  • EINECS:
  • MDL Number:MFCD30738017
  • Synonyms:ARV-771;ARV 771; ARV771;(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide;(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-;(2S,4R)-1-((2S)-2-(tert-butyl)-15-((6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,14-dioxo-6,10-dioxa-3,13-diazapentadecan-1-oyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide;Epigenetic Reader Domain,ARV-771,ARV771,inhibit,ARV 771,PROTACs,Inhibitor
Price18 Properties Safety Information Description
18 prices
Selected condition：
Brand
  • AK Scientific
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • DC Chemicals
  • Tocris
Package
  • 1mg
  • 5mg
  • 50mg
  • 5
  • 10mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2258EJ
  • Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-Chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide
  • Packaging10mg
  • Price$768
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573102
  • Product descriptionARV-771 >98%
  • Packaging100mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573102
  • Product descriptionARV-771 >98%
  • Packaging250mg
  • Price$2097.8
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb573102
  • Product descriptionARV-771 >98%
  • Packaging1g
  • Price$4173.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21299
  • Product descriptionARV-771
  • Packaging1mg
  • Price$57
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21299
  • Product descriptionARV-771
  • Packaging5mg
  • Price$141
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21299
  • Product descriptionARV-771
  • Packaging10mg
  • Price$253
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM328356
  • Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+
  • Packaging10mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM328356
  • Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+
  • Packaging50mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM328356
  • Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+
  • Packaging100mg
  • Price$390
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM328356
  • Product description(2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+
  • Packaging250mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6389
  • Product descriptionARV-771 99.82%
  • Packaging1mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6389
  • Product descriptionARV-771 99.82%
  • Packaging5mg
  • Price$420
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6389
  • Product descriptionARV-771 99.82%
  • Packaging10mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6389
  • Product descriptionARV-771 99.82%
  • Packaging50mg
  • Price$1800
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6389
  • Product descriptionARV-771 99.82%
  • Packaging100mg
  • Price$2520
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2258EJ (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-Chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide 10mg $768 2021-12-16 Buy
Biorbyt Ltd orb573102 ARV-771 >98% 100mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb573102 ARV-771 >98% 250mg $2097.8 2021-12-16 Buy
Biorbyt Ltd orb573102 ARV-771 >98% 1g $4173.5 2021-12-16 Buy
Cayman Chemical 21299 ARV-771 1mg $57 2024-03-01 Buy
Cayman Chemical 21299 ARV-771 5mg $141 2024-03-01 Buy
Cayman Chemical 21299 ARV-771 10mg $253 2024-03-01 Buy
Chemenu CM328356 (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+ 10mg $178 2021-12-16 Buy
Chemenu CM328356 (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+ 50mg $300 2021-12-16 Buy
Chemenu CM328356 (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+ 100mg $390 2021-12-16 Buy
Chemenu CM328356 (2S,4R)-1-[(2S)-2-[[2-[3-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]propoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3- 95%+ 250mg $780 2021-12-16 Buy
ChemScene CS-6389 ARV-771 99.82% 1mg $180 2021-12-16 Buy
ChemScene CS-6389 ARV-771 99.82% 5mg $420 2021-12-16 Buy
ChemScene CS-6389 ARV-771 99.82% 10mg $600 2021-12-16 Buy
ChemScene CS-6389 ARV-771 99.82% 50mg $1800 2021-12-16 Buy
ChemScene CS-6389 ARV-771 99.82% 100mg $2520 2021-12-16 Buy
Next Last

Properties

Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO:65.92(Max Conc. mg/mL);68.22(Max Conc. mM)
DMF:20.0(Max Conc. mg/mL);20.7(Max Conc. mM)
DMF:PBS (pH 7.2) (1:6):0.14(Max Conc. mg/mL);0.14(Max Conc. mM)
Ethanol:55.0(Max Conc. mg/mL);56.92(Max Conc. mM) form :A crystalline solid
pka :13.61±0.46(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ARV-771 is a BET PROTAC based on E3 ligase von Hippel-Lindau with Kds of 34 nM, 4.7 nM, 8.3 nM, 7.6 nM, 9.6 nM, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1) and BRD4(2), respectively.

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Suppliers and manufacturers

Hubei Chuchang Biotech Co., Ltd.
ARV-771
$0.00 /100MG
ARV-771 CAS:1949837-12-0
Wuhan Fortuna Chemical Co., Ltd
ARV-771
$0.00 /1mg
ARV-771 CAS:1949837-12-0
Shanghai finete Pharmaceutical Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
BOC Sciences
Zhengzhou Alfa Chemical Co.,Ltd
Career Henan Chemica Co
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem