ASP 2151
- $121 - $1700
- Product name: ASP 2151
- CAS: 841301-32-4
- MF: C24H26N4O5S
- MW: 482.55
- EINECS:
- MDL Number:MFCD19443709
- Synonyms:ASP 2151;AMenaMevir;N-(2,6-Dimethylphenyl)tetrahydro-N-[2-[[4-(1,2,4-oxadiazol-3-yl)phenyl]amino]-2-oxoethyl]-2H-thiopyran-4-carboxamide 1,1-dioxide;ASP 2151 (Amenamevir);CS-2753;ASP2151;ASP 2151;ASP-2151;N-(2,6-Dimethylphenyl)-N-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl] amino}-2-oxoethyl)-1,1-dioxothiane-4-carboxamide;N-(2-((4-(1,2,4-Oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-N-(2,6-dimethylphenyl)tetrahydro-2H-thiopyran-4-carboxamide 1,1-dioxide
13 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1G
- ManufacturerAK Scientific
- Product number7642CS
- Product descriptionAmenamevir
- Packaging1mg
- Price$233
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number7642CS
- Product descriptionAmenamevir
- Packaging10mg
- Price$969
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0013791
- Product descriptionASP-2151 95.00%
- Packaging1G
- Price$134.4
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number27921
- Product descriptionAmenamevir
- Packaging1mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27921
- Product descriptionAmenamevir
- Packaging5mg
- Price$452
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27921
- Product descriptionAmenamevir
- Packaging10mg
- Price$783
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number27921
- Product descriptionAmenamevir
- Packaging25mg
- Price$1652
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-8093
- Product descriptionAmenamevir 99.81%
- Packaging5mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-8093
- Product descriptionAmenamevir 99.81%
- Packaging10mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-8093
- Product descriptionAmenamevir 99.81%
- Packaging50mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-8093
- Product descriptionAmenamevir 99.81%
- Packaging100mg
- Price$950
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10621
- Product descriptionAmenamevir >98%
- Packaging250mg
- Price$1700
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberA576425
- Product descriptionAmenamevir
- Packaging50mg
- Price$730
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 7642CS | Amenamevir | 1mg | $233 | 2021-12-16 | Buy |
AK Scientific | 7642CS | Amenamevir | 10mg | $969 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0013791 | ASP-2151 95.00% | 1G | $134.4 | 2021-12-16 | Buy |
Cayman Chemical | 27921 | Amenamevir | 1mg | $121 | 2024-03-01 | Buy |
Cayman Chemical | 27921 | Amenamevir | 5mg | $452 | 2024-03-01 | Buy |
Cayman Chemical | 27921 | Amenamevir | 10mg | $783 | 2024-03-01 | Buy |
Cayman Chemical | 27921 | Amenamevir | 25mg | $1652 | 2024-03-01 | Buy |
ChemScene | CS-8093 | Amenamevir 99.81% | 5mg | $150 | 2021-12-16 | Buy |
ChemScene | CS-8093 | Amenamevir 99.81% | 10mg | $250 | 2021-12-16 | Buy |
ChemScene | CS-8093 | Amenamevir 99.81% | 50mg | $650 | 2021-12-16 | Buy |
ChemScene | CS-8093 | Amenamevir 99.81% | 100mg | $950 | 2021-12-16 | Buy |
DC Chemicals | DC10621 | Amenamevir >98% | 250mg | $1700 | 2021-12-16 | Buy |
TRC | A576425 | Amenamevir | 50mg | $730 | 2021-12-16 | Buy |
Properties
Density :1.360±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.08(Max Conc. mM)
DMF:2.0(Max Conc. mg/mL);4.14(Max Conc. mM) form :A solid
pka :12.60±0.70(Predicted)
color :White to off-white
storage temp. :Store at -20°C
solubility :DMF:PBS (pH 7.2) (1:20):0.04(Max Conc. mg/mL);0.08(Max Conc. mM)
DMF:2.0(Max Conc. mg/mL);4.14(Max Conc. mM) form :A solid
pka :12.60±0.70(Predicted)
color :White to off-white
Safety Information
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Description
Amenamevir is an antiviral inhibitor of herpes simplex virus 1 (HSV-1) helicase-primase complex activity. It inhibits recombinant HSV-1 helicase with an IC50 value of 0.078 μM and recombinant HSV-1 primase when used at concentrations greater than or equal to 0.03 μM. Amenamevir inhibits replication of varicella-zoster virus (VZV), HSV-1, and HSV-2 in human embryonic fibroblast (HEF) cells (EC50s = 0.047, 0.036, and 0.028 μM, respectively) and is not cytotoxic to HEF cells with a 50% cytotoxic concentration (CC50) of greater than 30 μM. Amenamevir also inhibits replication of clinical VZV isolates in HEF cells (EC50s = 0.038-0.10 μM). In vivo, it increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day).More related product prices
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