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ChemicalBook >> CAS DataBase List >> AST-1306

AST-1306

AST-1306 price.
  • $123 - $9740
  • Product name: AST-1306
  • CAS: 897383-62-9
  • MF: C24H18ClFN4O2
  • MW: 448.88
  • EINECS:
  • MDL Number:MFCD17169993
  • Synonyms:AST-1306;ALS 1306;N-[4-[[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]amino]quinazolin-6-yl]acrylamide;N-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide;Allitinib (AST1306);Allitinib;CS-590;N-(4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)acrylamide
19 prices
Selected condition:
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • TRC
Package
  • 100mg
  • 250mg
  • 1g
  • 1000mg
  • 10mM(in 1mL DMSO)
  • 5MG
  • 10MG
  • 50MG
  • 200mg
  • ManufacturerAK Scientific
  • Product number2230AH
  • Product descriptionN-[4-[[3-Chloro-4-[(3-fluorophenyl)-methoxy]-phenyl]-amino]-6-quinazolinyl]-2-propenamide
  • Packaging1g
  • Price$9740
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001438
  • Product descriptionN-[4-[[3-CHLORO-4-[(3-FLUORO PHENYL)-METHOXY]-PHENYL]-AMINO]-6-QUINAZOLINYL]-2-PROPENAMIDE 95.00%
  • Packaging5MG
  • Price$534.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001438
  • Product descriptionN-[4-[[3-CHLORO-4-[(3-FLUORO PHENYL)-METHOXY]-PHENYL]-AMINO]-6-QUINAZOLINYL]-2-PROPENAMIDE 95.00%
  • Packaging10MG
  • Price$1115.73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001438
  • Product descriptionN-[4-[[3-CHLORO-4-[(3-FLUORO PHENYL)-METHOXY]-PHENYL]-AMINO]-6-QUINAZOLINYL]-2-PROPENAMIDE 95.00%
  • Packaging50MG
  • Price$2134.44
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8367
  • Product descriptionAST-1306
  • Packaging5mg
  • Price$176
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8367
  • Product descriptionAST-1306
  • Packaging10mM(in 1mL DMSO)
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8367
  • Product descriptionAST-1306
  • Packaging10mg
  • Price$308
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8367
  • Product descriptionAST-1306
  • Packaging50mg
  • Price$836
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181197
  • Product descriptionAST-1306 >98%
  • Packaging100mg
  • Price$1133.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181197
  • Product descriptionAST-1306 >98%
  • Packaging250mg
  • Price$2245.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181197
  • Product descriptionAST-1306 >98%
  • Packaging1000mg
  • Price$4469.3
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM142791
  • Product descriptionN-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)acrylamide 98%
  • Packaging10mg
  • Price$201
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM142791
  • Product descriptionN-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)acrylamide 98%
  • Packaging50mg
  • Price$636
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000371
  • Product descriptionAST-1306 98+%
  • Packaging5mg
  • Price$123
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000371
  • Product descriptionAST-1306 98+%
  • Packaging10mg
  • Price$215
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000371
  • Product descriptionAST-1306 98+%
  • Packaging50mg
  • Price$680
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2230AH N-[4-[[3-Chloro-4-[(3-fluorophenyl)-methoxy]-phenyl]-amino]-6-quinazolinyl]-2-propenamide 1g $9740 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001438 N-[4-[[3-CHLORO-4-[(3-FLUORO PHENYL)-METHOXY]-PHENYL]-AMINO]-6-QUINAZOLINYL]-2-PROPENAMIDE 95.00% 5MG $534.6 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001438 N-[4-[[3-CHLORO-4-[(3-FLUORO PHENYL)-METHOXY]-PHENYL]-AMINO]-6-QUINAZOLINYL]-2-PROPENAMIDE 95.00% 10MG $1115.73 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001438 N-[4-[[3-CHLORO-4-[(3-FLUORO PHENYL)-METHOXY]-PHENYL]-AMINO]-6-QUINAZOLINYL]-2-PROPENAMIDE 95.00% 50MG $2134.44 2021-12-16 Buy
ApexBio Technology A8367 AST-1306 5mg $176 2021-12-16 Buy
ApexBio Technology A8367 AST-1306 10mM(in 1mL DMSO) $250 2021-12-16 Buy
ApexBio Technology A8367 AST-1306 10mg $308 2021-12-16 Buy
ApexBio Technology A8367 AST-1306 50mg $836 2021-12-16 Buy
Biorbyt Ltd orb181197 AST-1306 >98% 100mg $1133.9 2021-12-16 Buy
Biorbyt Ltd orb181197 AST-1306 >98% 250mg $2245.7 2021-12-16 Buy
Biorbyt Ltd orb181197 AST-1306 >98% 1000mg $4469.3 2021-12-16 Buy
Chemenu CM142791 N-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)acrylamide 98% 10mg $201 2021-12-16 Buy
Chemenu CM142791 N-(4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)acrylamide 98% 50mg $636 2021-12-16 Buy
Crysdot CD31000371 AST-1306 98+% 5mg $123 2021-12-16 Buy
Crysdot CD31000371 AST-1306 98+% 10mg $215 2021-12-16 Buy
Crysdot CD31000371 AST-1306 98+% 50mg $680 2021-12-16 Buy

Properties

Boiling point :655℃
Density :1.395
Flash point :350℃
storage temp. :Store at -20°C
solubility :≥22.45 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
pka :12.16±0.43(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

AST-1306 is a selective irreversible inhibitor of the epidermal growth factor receptor (EGFR) 1 and 2. Studies show that AST-1306 inhibited the enzymatic activities of wild-type EGF) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based systems. AST-1306 was more effective in inhibiting tumors with ErbB2-overexpressing cells than EGFR-overexpressing tumor.