ATN-224
|
- $68 - $2400
- Product name: ATN-224
- CAS: 649749-10-0
- MF: C5H14MoNOS4-
- MW: 328.36
- EINECS:
- MDL Number:MFCD25976790
- Synonyms:ATN-224;Bis(choline)tetrathioMolybdate;ATN-224 (Choline tetrathiomolybdate;WTX-101);Choline tetrathiomolybdate;CHOLINE TETRATHIOMOLYBDATE;WTX-101;WTX 101;WTX101;bis(sulfanylidene)molybdenum,2-hydroxyethyl(trimethyl)azanium,sulfanide;2-Hydroxy-N,N,N-trimethylethanaminium tetrathiomolybdate
13 prices
Selected condition：
Brand
- Biosynth Carbosynth
- Cayman Chemical
- Crysdot
- DC Chemicals
- Sigma-Aldrich
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 1g
- ManufacturerBiosynth Carbosynth
- Product numberFA167656
- Product descriptionATN-224
- Packaging1mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA167656
- Product descriptionATN-224
- Packaging2mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA167656
- Product descriptionATN-224
- Packaging5mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA167656
- Product descriptionATN-224
- Packaging10mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFA167656
- Product descriptionATN-224
- Packaging25mg
- Price$780
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23553
- Product descriptionATN-224 ≥95%
- Packaging1mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23553
- Product descriptionATN-224 ≥95%
- Packaging5mg
- Price$214
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23553
- Product descriptionATN-224 ≥95%
- Packaging10mg
- Price$365
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31001169
- Product descriptionATN-224 98+%
- Packaging10mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31001169
- Product descriptionATN-224 98+%
- Packaging50mg
- Price$630
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC20891
- Product descriptionATN-224 >98%
- Packaging1g
- Price$2400
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML3409
- Product descriptionATN-224 ≥95% (elemental analysis)
- Packaging5MG
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML3409
- Product descriptionATN-224 ≥95% (elemental analysis)
- Packaging25MG
- Price$327
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Biosynth Carbosynth | FA167656 | ATN-224 | 1mg | $120 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA167656 | ATN-224 | 2mg | $180 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA167656 | ATN-224 | 5mg | $300 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA167656 | ATN-224 | 10mg | $480 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA167656 | ATN-224 | 25mg | $780 | 2021-12-16 | Buy |
| Cayman Chemical | 23553 | ATN-224 ≥95% | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 23553 | ATN-224 ≥95% | 5mg | $214 | 2024-03-01 | Buy |
| Cayman Chemical | 23553 | ATN-224 ≥95% | 10mg | $365 | 2024-03-01 | Buy |
| Crysdot | CD31001169 | ATN-224 98+% | 10mg | $300 | 2021-12-16 | Buy |
| Crysdot | CD31001169 | ATN-224 98+% | 50mg | $630 | 2021-12-16 | Buy |
| DC Chemicals | DC20891 | ATN-224 >98% | 1g | $2400 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML3409 | ATN-224 ≥95% (elemental analysis) | 5MG | $81 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML3409 | ATN-224 ≥95% (elemental analysis) | 25MG | $327 | 2024-03-01 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMSO:20.0(Max Conc. mg/mL);46.24(Max Conc. mM)
DMSO:PBS (pH 7.2):0.5(Max Conc. mg/mL);1.16(Max Conc. mM) form :A crystalline solid
color :Pink to red
solubility :DMSO:20.0(Max Conc. mg/mL);46.24(Max Conc. mM)
DMSO:PBS (pH 7.2):0.5(Max Conc. mg/mL);1.16(Max Conc. mM) form :A crystalline solid
color :Pink to red
Safety Information
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Description
ATN-224 is a choline salt of tetrathiomolybdate and an inhibitor of superoxide dismutase 1 (SOD1; IC50s = 2.91 and 3.51 μM in human and mouse blood cells, respectively, in vitro). ATN-224 reduces the viability of cultured oxidative stress-resistant WEHI7.2 murine thymic lymphoma cells (EC50s = 5-6 nM) and human diffuse large B cell lymphoma cell lines (EC50s = 9.73-105.61 nM) independently of Bcl-2 and Bcl-xL. In vivo, ATN-224 (0.7 mg/kg) chelates copper to stabilize an antitumor viral vector, enhancing its efficacy against lung metastases in mice. It also inhibits angiogenesis in a mouse model (IC50s = 1.50-3 mg/kg via gavage).Suppliers and manufacturers
Hubei Jusheng Technology Co.,Ltd.
TargetMol Chemicals Inc.
Career Henan Chemica Co
InvivoChem
LEAPCHEM CO., LTD.
Shanghai Acmec Biochemical Technology Co., Ltd.
Amadis Chemical Company Limited
Shanghai Boyle Chemical Co., Ltd.
Beijing HwrkChemical Technology Co., Ltd
Lanzhou Angeli Biochemical Technology Co., Ltd.