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ChemicalBook >> CAS DataBase List >> AX 048

AX 048

AX 048 price.
  • $149 - $1366
  • Product name: AX 048
  • CAS: 873079-69-7
  • MF: C22H41NO4
  • MW: 383.57
  • EINECS:
  • MDL Number:MFCD09832585
  • Synonyms:AX 048;FMFKQXKYWWJNJS-UHFFFAOYSA-N;Butanoic acid, 4-[(1,2-dioxohexadecyl)amino]-, ethyl ester
4 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
Package
  • 500μg
  • 1mg
  • 5mg
  • ManufacturerAK Scientific
  • Product number1881CW
  • Product descriptionButanoicacid,4-((1,2-dioxohexadecyl)amino)-,ethylester
  • Packaging5mg
  • Price$1366
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13823
  • Product descriptionAX 048 ≥98%
  • Packaging500μg
  • Price$149
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13823
  • Product descriptionAX 048 ≥98%
  • Packaging1mg
  • Price$283
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number13823
  • Product descriptionAX 048 ≥98%
  • Packaging5mg
  • Price$969
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1881CW Butanoicacid,4-((1,2-dioxohexadecyl)amino)-,ethylester 5mg $1366 2021-12-16 Buy
Cayman Chemical 13823 AX 048 ≥98% 500μg $149 2024-03-01 Buy
Cayman Chemical 13823 AX 048 ≥98% 1mg $283 2024-03-01 Buy
Cayman Chemical 13823 AX 048 ≥98% 5mg $969 2024-03-01 Buy

Properties

Melting point :63-64 °C
Density :0.963±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 10 mg/ml; DMSO: 2 mg/ml; Ethanol: 5 mg/ml
form :A crystalline solid
pka :12.25±0.46(Predicted)

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes. AX 048 is a potent group IVA cPLA2 inhibitor that demonstrates 50% inhibition of the enzyme at a mole fraction (XI(50)) of 0.022. Pretreatment with AX 048 (ED50 = 1.2 mg/kg) dose-dependently reduces thermal hyperalgesia evoked by carrageenan injection of rat hind paw. At concentrations as high as 30 μM, AX 048 does not inhibit COX activity or interfere with central cannabinoid receptor signaling.