AZD1152
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- $65 - $1100
- Product name: AZD1152
- CAS: 722543-31-9
- MF: C26H31FN7O6P
- MW: 587.54
- EINECS:
- MDL Number:MFCD15146330
- Synonyms:1H-Pyrazole-3-acetamide, 5-[[7-[3-[ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-;AZD1152;5-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-3-acetamide;BARASERTIB; AZD-1152; AZD 1152;Barasertib (AZD1152);CS-1053;2-[[3-({4-[(5-{2-[(3-fluorophenyl)amino]-2-oxoethyl}-1H-pyrazol-3-yl)amino]quinazolin-7-yl}oxy)propyl](ethyl)amino]ethyl dihydrogen phosphate;2-(Ethyl(3-((4-((3-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-5-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyl dihydrogen phosphate
22 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- TRC
Package
- 1mg
- 2mg
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number8582CS
- Product descriptionBarasertib
- Packaging2mg
- Price$185
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0002466
- Product descriptionAZD-1152 HYDROCHLORIDE 95.00%
- Packaging5MG
- Price$496.24
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3214
- Product descriptionAZD1152
- Packaging50mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE18067
- Product description3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide
- Packaging1mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE18067
- Product description3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide
- Packaging2mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE18067
- Product description3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide
- Packaging5mg
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE18067
- Product description3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide
- Packaging10mg
- Price$350
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFE18067
- Product description3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide
- Packaging25mg
- Price$650
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13647
- Product descriptionAZD 1152 ≥95%
- Packaging1mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13647
- Product descriptionAZD 1152 ≥95%
- Packaging5mg
- Price$293
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13647
- Product descriptionAZD 1152 ≥95%
- Packaging10mg
- Price$488
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13647
- Product descriptionAZD 1152 ≥95%
- Packaging25mg
- Price$975
- Updated2021-12-16
- Buy
- ManufacturerChemenu
- Product numberCM142789
- Product description2-(ethyl(3-((4-((5-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyldihydrogenphosphate 95%
- Packaging10mg
- Price$234
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0978
- Product descriptionBarasertib 99.62%
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0978
- Product descriptionBarasertib 99.62%
- Packaging10mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0978
- Product descriptionBarasertib 99.62%
- Packaging50mg
- Price$470
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8582CS | Barasertib | 2mg | $185 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0002466 | AZD-1152 HYDROCHLORIDE 95.00% | 5MG | $496.24 | 2021-12-16 | Buy |
| ApexBio Technology | A3214 | AZD1152 | 50mg | $470 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE18067 | 3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide | 1mg | $65 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE18067 | 3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide | 2mg | $100 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE18067 | 3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide | 5mg | $210 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE18067 | 3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide | 10mg | $350 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FE18067 | 3-[[7-[3-[Ethyl[2-(phosphonooxy)ethyl]amino]propoxy]-4-quinazolinyl]amino]-N-(3-fluorophenyl)-1H-pyrazole-5-acetamide | 25mg | $650 | 2021-12-16 | Buy |
| Cayman Chemical | 13647 | AZD 1152 ≥95% | 1mg | $65 | 2021-12-16 | Buy |
| Cayman Chemical | 13647 | AZD 1152 ≥95% | 5mg | $293 | 2021-12-16 | Buy |
| Cayman Chemical | 13647 | AZD 1152 ≥95% | 10mg | $488 | 2021-12-16 | Buy |
| Cayman Chemical | 13647 | AZD 1152 ≥95% | 25mg | $975 | 2021-12-16 | Buy |
| Chemenu | CM142789 | 2-(ethyl(3-((4-((5-(2-((3-fluorophenyl)amino)-2-oxoethyl)-1H-pyrazol-3-yl)amino)quinazolin-7-yl)oxy)propyl)amino)ethyldihydrogenphosphate 95% | 10mg | $234 | 2021-12-16 | Buy |
| ChemScene | CS-0978 | Barasertib 99.62% | 5mg | $85 | 2021-12-16 | Buy |
| ChemScene | CS-0978 | Barasertib 99.62% | 10mg | $145 | 2021-12-16 | Buy |
| ChemScene | CS-0978 | Barasertib 99.62% | 50mg | $470 | 2021-12-16 | Buy |
Properties
Density :1.463
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL in DMSO
form :solid
pka :1.75±0.10(Predicted)
color :Off-white to light yellow
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
solubility :insoluble in H2O; insoluble in EtOH; ≥5.88 mg/mL in DMSO
form :solid
pka :1.75±0.10(Predicted)
color :Off-white to light yellow
Safety Information
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Description
AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50 = 0.36 nM). AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis followed by apoptosis. AZD 1152 inhibits tumor xenograft growth in vivo.More related product prices
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