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ChemicalBook >> CAS DataBase List >> Aftin-4

Aftin-4

Aftin-4 price.
  • $45 - $1500
  • Product name: Aftin-4
  • CAS: 866893-90-5
  • MF: C20H28N6O
  • MW: 368.48
  • EINECS:-0
  • MDL Number:MFCD30187584
  • Synonyms:Aftin-4;AFTIN-4;AFTIN 4;AFTIN4;N6-methyl-(R)-roscovitine;1-Butanol, 2-[[9-(1-methylethyl)-6-[methyl(phenylmethyl)amino]-9H-purin-2-yl]amino]-, (2R)-;Aftin-4 >=98% (HPLC);(R)-2-((6-(Benzyl(methyl)amino)-9-isopropyl-9H-purin-2-yl)amino)butan-1-ol;β-amyloid peptide,inhibit,Abeta,Amyloid-β,Aftin-4,Inhibitor
22 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 2mg
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-MR-C0014-M001
  • Product descriptionAftin-4 ≥98%(HPLC)
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8855CN
  • Product descriptionAftin-4
  • Packaging5mg
  • Price$324
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009881
  • Product descriptionAFTIN-4 95.00%
  • Packaging5MG
  • Price$454.49
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number27341
  • Product descriptionAftin-4
  • Packaging1mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27341
  • Product descriptionAftin-4
  • Packaging5mg
  • Price$202
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27341
  • Product descriptionAftin-4
  • Packaging10mg
  • Price$356
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number27341
  • Product descriptionAftin-4
  • Packaging25mg
  • Price$593
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0034791
  • Product descriptionAftin-4 98.13%
  • Packaging2mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0034791
  • Product descriptionAftin-4 98.13%
  • Packaging5mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0034791
  • Product descriptionAftin-4 98.13%
  • Packaging10mg
  • Price$240
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0034791
  • Product descriptionAftin-4 98.13%
  • Packaging25mg
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0034791
  • Product descriptionAftin-4 98.13%
  • Packaging50mg
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0034791
  • Product descriptionAftin-4 98.13%
  • Packaging100mg
  • Price$1500
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004939
  • Product descriptionAftin-4 97%
  • Packaging25mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004939
  • Product descriptionAftin-4 97%
  • Packaging50mg
  • Price$103
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004939
  • Product descriptionAftin-4 97%
  • Packaging1g
  • Price$632
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-MR-C0014-M001 Aftin-4 ≥98%(HPLC) 1mg $45 2021-12-16 Buy
AK Scientific 8855CN Aftin-4 5mg $324 2021-12-16 Buy
American Custom Chemicals Corporation INB0009881 AFTIN-4 95.00% 5MG $454.49 2021-12-16 Buy
Cayman Chemical 27341 Aftin-4 1mg $49 2024-03-01 Buy
Cayman Chemical 27341 Aftin-4 5mg $202 2024-03-01 Buy
Cayman Chemical 27341 Aftin-4 10mg $356 2024-03-01 Buy
Cayman Chemical 27341 Aftin-4 25mg $593 2024-03-01 Buy
ChemScene CS-0034791 Aftin-4 98.13% 2mg $75 2021-12-16 Buy
ChemScene CS-0034791 Aftin-4 98.13% 5mg $150 2021-12-16 Buy
ChemScene CS-0034791 Aftin-4 98.13% 10mg $240 2021-12-16 Buy
ChemScene CS-0034791 Aftin-4 98.13% 25mg $480 2021-12-16 Buy
ChemScene CS-0034791 Aftin-4 98.13% 50mg $850 2021-12-16 Buy
ChemScene CS-0034791 Aftin-4 98.13% 100mg $1500 2021-12-16 Buy
Crysdot CD31004939 Aftin-4 97% 25mg $77 2021-12-16 Buy
Crysdot CD31004939 Aftin-4 97% 50mg $103 2021-12-16 Buy
Crysdot CD31004939 Aftin-4 97% 1g $632 2021-12-16 Buy

Properties

storage temp. :-20°C
solubility :DMSO: soluble
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Aftin-4 is an inducer of amyloid-β (1-42) (Aβ42). It selectively increases extracellular Aβ42 over Aβ40 production in N2a-AβPP695 cells when used at concentrations ranging from 1 to 100 mM. In vivo, aftin-4 (3-20 nmol/animal, i.c.v.) increases hippocampal Aβ42 content, lipid peroxidation, and production of the pro-inflammatory cytokines IL-1β, IL-6, and TNF-α in mice. It also induces spatial working and spatial reference memory deficits in mice, effects that are reversed by co-administration of the γ-secretase inhibitor BMS-299,897.