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ChemicalBook >> CAS DataBase List >> Aloin

Aloin

Aloin price.
  • $32 - $261
  • Product name: Aloin
  • CAS: 452311-56-7
  • MF: C21H22O9
  • MW: 418.4
  • EINECS:
  • MDL Number:
  • Synonyms:9(10H)-Anthracenone, 10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-;10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
Price3 Properties Safety Information Description
3 prices
Selected condition：
Brand
  • Cayman Chemical
Package
  • 500mg
  • 1g
  • 5g
  • ManufacturerCayman Chemical
  • Product number22435
  • Product descriptionAloin
  • Packaging500mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22435
  • Product descriptionAloin
  • Packaging1g
  • Price$61
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number22435
  • Product descriptionAloin
  • Packaging5g
  • Price$261
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 22435 Aloin 500mg $32 2024-03-01 Buy
Cayman Chemical 22435 Aloin 1g $61 2024-03-01 Buy
Cayman Chemical 22435 Aloin 5g $261 2024-03-01 Buy

Properties

Boiling point :752.6±60.0 °C(Predicted)
Density :1.647±0.06 g/cm3(Predicted)
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.25 mg/ml; PBS (pH 7.2): 0.5 mg/ml
form :A crystalline solid
pka :7.12±0.40(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

Aloin is a mixture of aloin A and aloin B , anthraquinones found in Aloe vera, and has diverse biological activities. It reduces IL-6 and TNF-α expression as well as nitric oxide (NO) production and COX-2 and inducible NO synthase (iNOS) expression in LPS-stimulated RAW 264.7 cells when used at concentrations ranging from 100 to 400 mM. Aloin inhibits LPS-induced p65 acetylation, nuclear translocation of NF-kB, and apoptosis in RAW 264.7 cells. It reduces motility of T. congolense in vitro and reduces the number of parasites in T. congolense-infected mice when administered at a dose of 400 mg/kg. Aloin (50 and 100 mg/kg) also reduces activity of glutathione peroxidase (GPX), glutathione-S-transferase (GST), and glutathione reductase (GR), the level of colonic malondialdehyde (MDA), and the number of aberrant crypt foci and mucin-depleted foci in a rat model of 1,2-dimethylhydrazine-induced colon cancer.

Suppliers and manufacturers

Shanghai Yifei Biotechnology Co. , Ltd.