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ChemicalBook >> CAS DataBase List >> Antimycin A4

Antimycin A4

Antimycin A4 price.
  • $231 - $1096
  • Product name: Antimycin A4
  • CAS: 27220-59-3
  • MF: C25H34N2O9
  • MW: 506.54546
  • EINECS:248-343-7
  • MDL Number:
  • Synonyms:8-butyl-3-(3-formamido-2-hydroxybenzamido)-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl butyrate ;8-Butyl-3-[[3-(formylamino)-2-hydroxybenzoyl]amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonane-7-yl=butyrate;Butyric acid 8-butyl-3-[(3-formylamino-2-hydroxybenzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl ester;antimycin A4;Antimycin A4 DISCONTINUED, offer A697508;Antimycin A4 (7CI,9CI)
Price3 Properties Safety Information Description
3 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
Package
  • 500μg
  • 2.5mg
  • 5MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010163
  • Product descriptionANTIMYCIN A4 95.00%
  • Packaging5MG
  • Price$504.44
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21999
  • Product descriptionAntimycin A4 ≥98%
  • Packaging500μg
  • Price$231
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21999
  • Product descriptionAntimycin A4 ≥98%
  • Packaging2.5mg
  • Price$1096
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0010163 ANTIMYCIN A4 95.00% 5MG $504.44 2021-12-16 Buy
Cayman Chemical 21999 Antimycin A4 ≥98% 500μg $231 2024-03-01 Buy
Cayman Chemical 21999 Antimycin A4 ≥98% 2.5mg $1096 2024-03-01 Buy

Properties

Boiling point :595.17°C (rough estimate)
Density :1.3028 (rough estimate)
refractive index :1.5500 (estimate)
storage temp. :-20°C
solubility :DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form :A solid

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger GHS hazard pictograms P280, P302+P352, P312, P322, P361,P363, P405, P501
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger GHS hazard pictograms P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P311 Call a POISON CENTER or doctor/physician.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P322 Specific measures (see …on this label).
P330 Rinse mouth.
P361 Remove/Take off immediately all contaminated clothing.
P363 Wash contaminated clothing before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Antimycin A4 is an active component of the antimycin A antibiotic complex that is more polar than antimycin A1 , antimycin A2 , and antimycin A3 . Antimycin A4 inhibits ATP-citrate lyase with a Ki value of 64.8 μM. The antimycin A complex is a mixture of antimycins A1, A2, A3, and A4 that demonstrates antifungal, insecticidal, nematocidal, and piscicidal properties. It blocks mitochondrial respiration and can deplete cellular levels of ATP via inhibition of complex III of the mitochondrial electron transport chain (ETC). Antimycin A prevents the transfer of electrons between the b-cytochromes and ubiquinone at the Q(inner) site of complex III. This results in the stabilization of the ubisemiquinone radical at the Q(outer) site of complex III, leading to increased production of superoxide. Antimycin A is widely used in research to shunt electron flow through the ETC to study the chemical details of oxygen respiration. Additionally, antimycin A has been shown to inhibit Bcl-2 and Bcl-xL proteins, inducing apoptosis.

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BOC Sciences Lynnchem Novachemistry Shanghai Hongye Biotechnology Co. Ltd Shenzhen Polymeri Biochemical Technology Co., Ltd. ChemeGen(Shanghai) Biotechnology Co.,Ltd. Meng Cheng Technology (Shanghai) Co., LTD Energy Chemical Shanghai Universal Biotech Co.,Ltd TargetMol Chemicals Inc.