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ChemicalBook >> CAS DataBase List >> BC-1258

BC-1258

BC-1258 price.
  • $105 - $1600
  • Product name: BC-1258
  • CAS: 1507370-40-2
  • MF: C22H22N4S2
  • MW: 406.57
  • EINECS:
  • MDL Number:MFCD28137686
  • Synonyms:N,N′-Bis-(4-thiazol-2-yl-benzyl)-ethane-1,2-diamine;BC-1258;N,N'-bis[[4-(1,3-thiazol-2-yl)phenyl]methyl]ethane-1,2-diamine;1,2-Ethanediamine, N1,N2-bis[[4-(2-thiazolyl)phenyl]methyl]-;LRR,F-box,inhibit,repeat,BC-?1258,BC ?1258,FBXL2,Apoptosis,tumor,Inhibitor,BC?1258;N1,N2-Bis(4-(thiazol-2-yl)benzyl)ethane-1,2-diamine;LRR|||F-box|||BC1258|||inhibit|||repeat|||BC-1258|||BC-1258|||BC-?1258|||BC ?1258|||FBXL2|||Apoptosis|||BC-1258|||tumor|||Inhibitor|||BC?1258|||BC 1258
Price4 Properties Safety Information Description
4 prices
Selected condition：
Brand
  • AK Scientific
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 5mg
  • 25mg
  • 100mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5045
  • Product descriptionBC-1258
  • Packaging100mg
  • Price$830
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC43054
  • Product descriptionBC-1258 >98%
  • Packaging1g
  • Price$1600
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1021
  • Product descriptionBC-1258 ≥98% (HPLC)
  • Packaging5mg
  • Price$105
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML1021
  • Product descriptionBC-1258 ≥98% (HPLC)
  • Packaging25mg
  • Price$423
  • Updated2022-05-15
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5045 BC-1258 100mg $830 2021-12-16 Buy
DC Chemicals DC43054 BC-1258 >98% 1g $1600 2021-12-16 Buy
Sigma-Aldrich SML1021 BC-1258 ≥98% (HPLC) 5mg $105 2022-05-15 Buy
Sigma-Aldrich SML1021 BC-1258 ≥98% (HPLC) 25mg $423 2022-05-15 Buy

Properties

storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear (warmed)
form :powder
color :white to beige
InChI :InChI=1S/C22H22N4S2/c1-5-19(21-25-11-13-27-21)6-2-17(1)15-23-9-10-24-16-18-3-7-20(8-4-18)22-26-12-14-28-22/h1-8,11-14,23-24H,9-10,15-16H2
InChIKey :FRTSLZJCGAFSET-UHFFFAOYSA-N
SMILES :C(NCC1=CC=C(C2=NC=CS2)C=C1)CNCC1=CC=C(C2=NC=CS2)C=C1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

BC-1258 (N,N′-Bis-(4-thiazol-2-yl-benzyl)-ethane-1,2-diamine) is a potent activator of unique E3 ligase F-box/LRR-repeat protein 2 (FBXL2) that increases levels of FBXLs protein, thus promoting Aurora B degradation. BC-1258 induces mitotic arrest and apoptosis of tumorigenic cells. Also BC-1258 inhibits tumor formation in athymic nude mice.

Suppliers and manufacturers

Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Hangzhou MolCore BioPharmatech Co.,Ltd.
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Wuhan Jingkang en Biomedical Technology Co., Ltd
Amadis Chemical Company Limited Pharmacodia (Beijing) Co.,Ltd Shanghai EFE Biological Technology Co., Ltd. Tianjin Kailiqi Biotechnology Co., Ltd. Shanghai Rechem science Co., Ltd.