(-)-BETA-HYDRASTINE
- $55 - $1175
- Product name: (-)-BETA-HYDRASTINE
- CAS: 118-08-1
- MF: C21H21NO6
- MW: 383.39
- EINECS:204-233-0
- MDL Number:MFCD00152561
- Synonyms:HYDRASTINE, (-)-B-(P) (AHP Verified);HYDRASTINE, (-)-B-(P);Hydrastine (base and/or unspecified salts);(1R,9S)-(-)-β-Hydrastine;(3R)-6,7-Dimethoxy-3-[[(1R)-1,2,3,4-tetrahydro-2-methyl-6,7-(methylenedioxy)isoquinoline]-1-yl]isobenzofuran-1(3H)-one;[R,(-)]-6,7-Dimethoxy-3-[[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinoline]-5-yl]isobenzofuran-1(3H)-one;(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranone;[S,(-)]-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]isobenzofuran-1(3H)-one
14 prices
Selected condition:
Brand
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- Biorbyt Ltd
- Cayman Chemical
- Crysdot
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 5g
- ManufacturerAHH
- Product numberMT-52735
- Product descriptionHydrastine 98%
- Packaging5g
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number6606AF
- Product descriptionHydrastine
- Packaging10mg
- Price$241
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPXT0001683
- Product descriptionHYDRASTINE 98.00%
- Packaging10MG
- Price$716.1
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS348789
- Product descriptionHydrastine
- Packaging10mg
- Price$378
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb611709
- Product descriptionHydrastine
- Packaging10mg
- Price$248.2
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number22363
- Product description(1R,9S)-(–)-β-Hydrastine ≥98%
- Packaging5mg
- Price$68
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22363
- Product description(1R,9S)-(–)-β-Hydrastine ≥98%
- Packaging10mg
- Price$130
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22363
- Product description(1R,9S)-(–)-β-Hydrastine ≥98%
- Packaging25mg
- Price$235
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number22363
- Product description(1R,9S)-(–)-β-Hydrastine ≥98%
- Packaging50mg
- Price$401
- Updated2024-03-01
- Buy
- ManufacturerCrysdot
- Product numberCD31004394
- Product descriptionHydrastine 98+%
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD31004394
- Product descriptionHydrastine 98+%
- Packaging10mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC23931
- Product descriptionHydrastine >98%
- Packaging10mg
- Price$88
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number1313210
- Product description(1R,9S)-(?)-β-Hydrastine United States Pharmacopeia (USP) Reference Standard
- Packaging10mg
- Price$644
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberH675701
- Product description(-)-β-Hydrastine
- Packaging50mg
- Price$1175
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | MT-52735 | Hydrastine 98% | 5g | $230 | 2021-12-16 | Buy |
AK Scientific | 6606AF | Hydrastine | 10mg | $241 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PXT0001683 | HYDRASTINE 98.00% | 10MG | $716.1 | 2021-12-16 | Buy |
Arctom | AS348789 | Hydrastine | 10mg | $378 | 2021-12-16 | Buy |
Biorbyt Ltd | orb611709 | Hydrastine | 10mg | $248.2 | 2021-12-16 | Buy |
Cayman Chemical | 22363 | (1R,9S)-(–)-β-Hydrastine ≥98% | 5mg | $68 | 2024-03-01 | Buy |
Cayman Chemical | 22363 | (1R,9S)-(–)-β-Hydrastine ≥98% | 10mg | $130 | 2024-03-01 | Buy |
Cayman Chemical | 22363 | (1R,9S)-(–)-β-Hydrastine ≥98% | 25mg | $235 | 2024-03-01 | Buy |
Cayman Chemical | 22363 | (1R,9S)-(–)-β-Hydrastine ≥98% | 50mg | $401 | 2024-03-01 | Buy |
Crysdot | CD31004394 | Hydrastine 98+% | 5mg | $55 | 2021-12-16 | Buy |
Crysdot | CD31004394 | Hydrastine 98+% | 10mg | $76 | 2021-12-16 | Buy |
DC Chemicals | DC23931 | Hydrastine >98% | 10mg | $88 | 2021-12-16 | Buy |
Sigma-Aldrich | 1313210 | (1R,9S)-(?)-β-Hydrastine United States Pharmacopeia (USP) Reference Standard | 10mg | $644 | 2024-03-01 | Buy |
TRC | H675701 | (-)-β-Hydrastine | 50mg | $1175 | 2021-12-16 | Buy |
Properties
Melting point :132℃
alpha :D20 -50° (c = 0.3 in abs alc)
Boiling point :510.32°C (rough estimate)
Density :1.339±0.06 g/cm3 (20 ºC 760 Torr)
refractive index :1.5614 (estimate)
storage temp. :−20°C
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :7.8(at 25℃)
color :White to light yellow
Water Solubility :30mg/L(20 ºC)
CAS DataBase Reference :118-08-1(CAS DataBase Reference)
alpha :D20 -50° (c = 0.3 in abs alc)
Boiling point :510.32°C (rough estimate)
Density :1.339±0.06 g/cm3 (20 ºC 760 Torr)
refractive index :1.5614 (estimate)
storage temp. :−20°C
solubility :DMF: 10 mg/ml; DMSO: 10 mg/ml
form :A crystalline solid
pka :7.8(at 25℃)
color :White to light yellow
Water Solubility :30mg/L(20 ºC)
CAS DataBase Reference :118-08-1(CAS DataBase Reference)
Safety Information
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Signal word: | Warning | ||||||||||||||
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Description
(1R,9S)-(–)-β-Hydrastine is an enantiomer of the alkaloid hydrastine that inhibits dopamine biosynthesis (IC50 = 20.7 μM in PC12 cells) by inhibiting tyrosine hydroxylase activity. It inhibits dopamine release with an IC50 value of 66.5 μM in the presence of high extracellular K+ levels. It also inhibits L-type and caffeine-activated store-operated Ca2+ channels and prevents Ca2+ leakage from intracellular stores.Related product price
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