BIBB 515
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- $44 - $715.52
- Product name: BIBB 515
- CAS: 156635-05-1
- MF: C22H21ClN2O2
- MW: 380.87
- EINECS:
- MDL Number:MFCD00930515
- Synonyms:BIBB 515;(4-chlorophenyl)-[4-[[4-(4,5-dihydro-1,3-oxazol-2-yl)phenyl]methylidene]piperidin-1-yl]methanone;Methanone, (4-chlorophenyl)[4-[[4-(4,5-dihydro-2-oxazolyl)phenyl]methylene]-1-piperidinyl]-;BIBB 515,Inhibitor,OSC,inhibit,cyclase,effect,metabolism,LDL,BIBB-515,2,3-oxidosqualene,BIBB515,sterol,cholesterol,lipid-lowering
9 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Cayman Chemical
Package
- 1MG
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number3666CC
- Product description1-(4-Chlorobenzoyl)-4-((4-(2-oxazolin-2-yl)benzylidene))piperidine
- Packaging5mg
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3666CC
- Product description1-(4-Chlorobenzoyl)-4-((4-(2-oxazolin-2-yl)benzylidene))piperidine
- Packaging10mg
- Price$181
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000098
- Product descriptionBIBB-515 95.00%
- Packaging1MG
- Price$555.44
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000098
- Product descriptionBIBB-515 95.00%
- Packaging5MG
- Price$617.46
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000098
- Product descriptionBIBB-515 95.00%
- Packaging25MG
- Price$715.52
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10010517
- Product descriptionBIBB 515 ≥98%
- Packaging5mg
- Price$44
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010517
- Product descriptionBIBB 515 ≥98%
- Packaging10mg
- Price$74
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010517
- Product descriptionBIBB 515 ≥98%
- Packaging50mg
- Price$299
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010517
- Product descriptionBIBB 515 ≥98%
- Packaging100mg
- Price$469
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3666CC | 1-(4-Chlorobenzoyl)-4-((4-(2-oxazolin-2-yl)benzylidene))piperidine | 5mg | $147 | 2021-12-16 | Buy |
| AK Scientific | 3666CC | 1-(4-Chlorobenzoyl)-4-((4-(2-oxazolin-2-yl)benzylidene))piperidine | 10mg | $181 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000098 | BIBB-515 95.00% | 1MG | $555.44 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000098 | BIBB-515 95.00% | 5MG | $617.46 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000098 | BIBB-515 95.00% | 25MG | $715.52 | 2021-12-16 | Buy |
| Cayman Chemical | 10010517 | BIBB 515 ≥98% | 5mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 10010517 | BIBB 515 ≥98% | 10mg | $74 | 2024-03-01 | Buy |
| Cayman Chemical | 10010517 | BIBB 515 ≥98% | 50mg | $299 | 2024-03-01 | Buy |
| Cayman Chemical | 10010517 | BIBB 515 ≥98% | 100mg | $469 | 2024-03-01 | Buy |
Properties
Boiling point :586.5±50.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:1.38(Max Conc. mg/mL);3.62(Max Conc. mM)
DMF:0.3(Max Conc. mg/mL);0.79(Max Conc. mM)
Ethanol:0.15(Max Conc. mg/mL);0.39(Max Conc. mM) form :White solid.
pka :4.72±0.50(Predicted)
color :White to off-white
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO:1.38(Max Conc. mg/mL);3.62(Max Conc. mM)
DMF:0.3(Max Conc. mg/mL);0.79(Max Conc. mM)
Ethanol:0.15(Max Conc. mg/mL);0.39(Max Conc. mM) form :White solid.
pka :4.72±0.50(Predicted)
color :White to off-white
Safety Information
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Description
BIBB 515 is a selective and potent inhibitor of 2,3-oxidosqualene cyclase (OSC) with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. Total cholesterol was reduced by 19% in normalipemic hamsters at a dose of 55 mg/kg/day for 11 days and 25% in hyperlipemic hamsters at a dose of 148 mg/kg/day for 25 days. OSC is an important enzyme in the biosynthesis of animal, fungal and plant sterols. OSC catalyzes the conversion of (3S)-2,3-oxidosqualene to lanosterol, a precursor to cholesterol, in fungi and mammals.More related product prices
RO 48-8071Related product price
- RO 48-8071
$44-1500 - (4-Chlorophenyl)(piperidin-1-yl)methanone
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$500.6
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