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ChemicalBook >> CAS DataBase List >> BINUCLEINE 2

BINUCLEINE 2

BINUCLEINE 2 price.
  • $36 - $725.46
  • Product name: BINUCLEINE 2
  • CAS: 220088-42-6
  • MF: C13H11ClFN5
  • MW: 291.71
  • EINECS:
  • MDL Number:MFCD00177827
  • Synonyms:Binucleine 2 - CAS 220088-42-6 - Calbiochem;N'-[2-(3-chloro-4-fluorophenyl)-4-cyanopyrazol-3-yl]-N,N-dimethylmethanimidamide;Methanimidamide, N'-[1-(3-chloro-4-fluorophenyl)-4-cyano-1H-pyrazol-5-yl]-N,N-dimethyl-
Price7 Properties Safety Information Description
7 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • Sigma-Aldrich
Package
  • 1mg
  • 2MG
  • 5MG
  • 10mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001278
  • Product descriptionBINUCLEINE 2 95.00%
  • Packaging2MG
  • Price$587.43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0001278
  • Product descriptionBINUCLEINE 2 95.00%
  • Packaging5MG
  • Price$725.46
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23367
  • Product descriptionBinucleine 2 ≥98%
  • Packaging1mg
  • Price$36
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23367
  • Product descriptionBinucleine 2 ≥98%
  • Packaging5mg
  • Price$143
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23367
  • Product descriptionBinucleine 2 ≥98%
  • Packaging10mg
  • Price$269
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB1186
  • Product descriptionBinucleine 2 ≥97% (HPLC)
  • Packaging2mg
  • Price$104
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB1186
  • Product descriptionBinucleine 2 ≥97% (HPLC)
  • Packaging5mg
  • Price$210
  • Updated2023-01-07
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation KIN0001278 BINUCLEINE 2 95.00% 2MG $587.43 2021-12-16 Buy
American Custom Chemicals Corporation KIN0001278 BINUCLEINE 2 95.00% 5MG $725.46 2021-12-16 Buy
Cayman Chemical 23367 Binucleine 2 ≥98% 1mg $36 2024-03-01 Buy
Cayman Chemical 23367 Binucleine 2 ≥98% 5mg $143 2024-03-01 Buy
Cayman Chemical 23367 Binucleine 2 ≥98% 10mg $269 2024-03-01 Buy
Sigma-Aldrich B1186 Binucleine 2 ≥97% (HPLC) 2mg $104 2024-03-01 Buy
Sigma-Aldrich B1186 Binucleine 2 ≥97% (HPLC) 5mg $210 2023-01-07 Buy

Properties

Boiling point :456.9±55.0 °C(Predicted)
Density :1.30±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >5 mg/mL, soluble
form :solid
pka :4.81±0.50(Predicted)
Stability :Moisture Sensitive

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Binucleine 2 is a cell-permeable pyrazolo compound that inhibits cytokinesis function of the ARK-2 pathway. It inhibits Histone H3 phosphorylation on Ser10 in mitotic Drosophila Kc167 cells at 20 μM, while inactive in mammalian systems. Binucleine 2 does neither function as a general kinase inhibitor nor inhibit Cdk-dependent entry into mitosis.

Suppliers and manufacturers

Aladdin Scientific BOC Sciences Shanghai EFE Biological Technology Co., Ltd. Shanghai Hongye Biotechnology Co. Ltd Jinan ponder chemical co. LTD Energy Chemical TargetMol Chemicals Inc.