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ChemicalBook >> CAS DataBase List >> BMS 181176

BMS 181176

BMS 181176 price.
  • $214 - $761
  • Product name: BMS 181176
  • CAS: 119673-08-4
  • MF: C33H34Cl2N4O7
  • MW: 669.559
  • EINECS:
  • MDL Number:MFCD14635404
  • Synonyms:BMS 181176;Becatecarin;5H-Indolo[2,3-A]pyrrolo[3,4-C]carbazole-5,7(6H)-dione, 1,11-.beta.-D-glucopyranosyl)-;Bmy 27557;Bacatecarin;JSKFWUPVIZYJMR-UDOAKELVSA-N;5H-Indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione, 1,11-dichloro-6-[2-(diethylamino)ethyl]-12,13-dihydro-12-(4-O-methyl-β-D-glucopyranosyl)-
5 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • TRC
  • Usbiological
Package
  • 250ug
  • 250μg
  • 1mg
  • ManufacturerAK Scientific
  • Product numberX2117
  • Product descriptionBecatecarin
  • Packaging1mg
  • Price$761
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15576
  • Product descriptionBecatecarin ≥98%
  • Packaging250μg
  • Price$214
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15576
  • Product descriptionBecatecarin ≥98%
  • Packaging1mg
  • Price$595
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberB131078
  • Product descriptionBecatecarin
  • Packaging250μg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number207087
  • Product descriptionBecatecarin
  • Packaging250ug
  • Price$392
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X2117 Becatecarin 1mg $761 2021-12-16 Buy
Cayman Chemical 15576 Becatecarin ≥98% 250μg $214 2024-03-01 Buy
Cayman Chemical 15576 Becatecarin ≥98% 1mg $595 2024-03-01 Buy
TRC B131078 Becatecarin 250μg $280 2021-12-16 Buy
Usbiological 207087 Becatecarin 250ug $392 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO: Soluble; Water: Soluble
form :Yellow solid.
color :Yellow

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Becatecarin is a water-soluble, diethylaminoethyl analog of the antineoplastic antibiotic rebeccamycin. It intercalates into DNA, stabilizing the DNA-topoisomerase complex. This results in the potent catalytic inhibition of both topoisomerases I and II, initiating DNA cleavage and apoptosis. Becatecarin, alone or in combination with other compounds, has anti-cancer as well as myelosuppressive effects in vivo. It is also a transport substrate of the ATP-binding cassette (ABC) transporter ABCG2.

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