BMS453
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- $37 - $950
- Product name: BMS453
- CAS: 166977-43-1
- MF: C27H24O2
- MW: 380.48
- EINECS:
- MDL Number:MFCD18086870
- Synonyms:BMS453;4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid;(E)-4-[2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid;Benzoic acid, 4-[(1E)-2-(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-;(E)-4-[2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid;BMS-189453 (BMS189453;Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X receptors,BMS189453,arrest,cell,RARα,Retinoic acid receptors
13 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 250mg
- ManufacturerAK Scientific
- Product numberSYN5134
- Product descriptionBMS-453
- Packaging50mg
- Price$605
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7396
- Product descriptionBMS453
- Packaging10mg
- Price$339
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19076
- Product descriptionBMS 453 ≥98%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19076
- Product descriptionBMS 453 ≥98%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19076
- Product descriptionBMS 453 ≥98%
- Packaging10mg
- Price$178
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19076
- Product descriptionBMS 453 ≥98%
- Packaging25mg
- Price$353
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0019762
- Product descriptionBMS453 ≥98.0%
- Packaging5mg
- Price$320
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC22988
- Product descriptionBMS-189453 >98%
- Packaging250mg
- Price$950
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1149
- Product descriptionBMS-189453 ≥98% (HPLC)
- Packaging5mg
- Price$132
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1149
- Product descriptionBMS-189453 ≥98% (HPLC)
- Packaging25mg
- Price$535
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number3409
- Product descriptionBMS453 ≥98%(HPLC)
- Packaging10
- Price$229
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB596410
- Product descriptionBMS453
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number254791
- Product descriptionBMS 453
- Packaging10mg
- Price$480
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5134 | BMS-453 | 50mg | $605 | 2021-12-16 | Buy |
| ApexBio Technology | B7396 | BMS453 | 10mg | $339 | 2021-12-16 | Buy |
| Cayman Chemical | 19076 | BMS 453 ≥98% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 19076 | BMS 453 ≥98% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 19076 | BMS 453 ≥98% | 10mg | $178 | 2024-03-01 | Buy |
| Cayman Chemical | 19076 | BMS 453 ≥98% | 25mg | $353 | 2024-03-01 | Buy |
| ChemScene | CS-0019762 | BMS453 ≥98.0% | 5mg | $320 | 2021-12-16 | Buy |
| DC Chemicals | DC22988 | BMS-189453 >98% | 250mg | $950 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1149 | BMS-189453 ≥98% (HPLC) | 5mg | $132 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1149 | BMS-189453 ≥98% (HPLC) | 25mg | $535 | 2024-03-01 | Buy |
| Tocris | 3409 | BMS453 ≥98%(HPLC) | 10 | $229 | 2021-12-16 | Buy |
| TRC | B596410 | BMS453 | 10mg | $160 | 2021-12-16 | Buy |
| Usbiological | 254791 | BMS 453 | 10mg | $480 | 2021-12-16 | Buy |
Properties
Boiling point :560.9±50.0 °C(Predicted)
Density :1.167±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :4.27±0.10(Predicted)
color :white to beige
Density :1.167±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO: soluble10mg/mL, clear
form :powder
pka :4.27±0.10(Predicted)
color :white to beige
Safety Information
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Description
Nuclear retinoic acid receptors (RARs) are transcriptional regulators with roles in cell proliferation and differentiation. BMS 453 is a synthetic retinoid that acts as an agonist of RARβ and an antagonist of RARα and RARγ. It has been shown to inhibit the proliferation of normal breast cells via the induction of TGF-β activity, causing G1 arrest. BMS 453 binding to RARα and RARγ can induce a transrepression of phorbol ester-induced AP-1 activity (IC50s = ~0.1 nM in HeLa and MCSF-7 cells), which also correlates with reduced cell proliferation. BM 453 has been used to trigger the differentiation of mouse embryonic stem cells (mES) in a study of RARβ-induced mES cell adipogenesis.Suppliers and manufacturers
Career Henan Chemica Co
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Hangzhou MolCore BioPharmatech Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd
Aladdin Scientific
Wuhan Jingkang en Biomedical Technology Co., Ltd
Amadis Chemical Company Limited
3B Pharmachem (Wuhan) International Co.,Ltd.
