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ChemicalBook >> CAS DataBase List >> BRD73954

BRD73954

BRD73954 price.
  • $10 - $931
  • Product name: BRD73954
  • CAS: 1440209-96-0
  • MF: C16H16N2O3
  • MW: 284.31
  • EINECS:-0
  • MDL Number:MFCD26383435
  • Synonyms:N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide;BRD73954;N1-hydroxy-N3-phenethylisophthalamide;N1-hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide BRD73954;BRD73954, 1-N-hydroxy-3-N-(2-phenylethyl)benzene-1,3-dicarboxamide;BRD-73954;BRD 73954;CS-1777;1,3-Benzenedicarboxamide, N1-hydroxy-N3-(2-phenylethyl)-
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
Package
  • 10
  • 1mg
  • 5mg
  • 2x5mg
  • 10mg
  • 50
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1707DV
  • Product description3-N-Hydroxy-1-N-(2-phenylethyl)benzene-1,3-dicarboxamide
  • Packaging250mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5469
  • Product descriptionBRD73954
  • Packaging100mg
  • Price$931
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA985320
  • Product descriptionBRD73954 98+%
  • Packaging5mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA985320
  • Product descriptionBRD73954 98+%
  • Packaging10mg
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA985320
  • Product descriptionBRD73954 98+%
  • Packaging25mg
  • Price$20
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA985320
  • Product descriptionBRD73954 98+%
  • Packaging50mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA985320
  • Product descriptionBRD73954 98+%
  • Packaging100mg
  • Price$44
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA985320
  • Product descriptionBRD73954 98+%
  • Packaging250mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA985320
  • Product descriptionBRD73954 98+%
  • Packaging1g
  • Price$160
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009762
  • Product descriptionBRD-73954 95.00%
  • Packaging5MG
  • Price$459.2
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4988
  • Product descriptionBRD73954
  • Packaging5mg
  • Price$156
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4988
  • Product descriptionBRD73954
  • Packaging10mg
  • Price$260
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB4988
  • Product descriptionBRD73954
  • Packaging25mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB4988
  • Product descriptionBRD73954
  • Packaging50mg
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2471
  • Product descriptionBRD73954 99%
  • Packaging5mg
  • Price$93.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2471
  • Product descriptionBRD73954 99%
  • Packaging2x5mg
  • Price$132
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1707DV 3-N-Hydroxy-1-N-(2-phenylethyl)benzene-1,3-dicarboxamide 250mg $189 2021-12-16 Buy
AK Scientific SYN5469 BRD73954 100mg $931 2021-12-16 Buy
Ambeed A985320 BRD73954 98+% 5mg $10 2021-12-16 Buy
Ambeed A985320 BRD73954 98+% 10mg $14 2021-12-16 Buy
Ambeed A985320 BRD73954 98+% 25mg $20 2021-12-16 Buy
Ambeed A985320 BRD73954 98+% 50mg $30 2021-12-16 Buy
Ambeed A985320 BRD73954 98+% 100mg $44 2021-12-16 Buy
Ambeed A985320 BRD73954 98+% 250mg $66 2021-12-16 Buy
Ambeed A985320 BRD73954 98+% 1g $160 2021-12-16 Buy
American Custom Chemicals Corporation INB0009762 BRD-73954 95.00% 5MG $459.2 2021-12-16 Buy
ApexBio Technology B4988 BRD73954 5mg $156 2021-12-16 Buy
ApexBio Technology B4988 BRD73954 10mg $260 2021-12-16 Buy
ApexBio Technology B4988 BRD73954 25mg $520 2021-12-16 Buy
ApexBio Technology B4988 BRD73954 50mg $780 2021-12-16 Buy
Axon Medchem Axon2471 BRD73954 99% 5mg $93.5 2021-12-16 Buy
Axon Medchem Axon2471 BRD73954 99% 2x5mg $132 2021-12-16 Buy

Properties

Melting point :172-175oC
Density :1.245±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :8.56±0.10(Predicted)
color :Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

BRD73954 is a dual inhibitor of histone deacetylase 6 (HDAC6) and HDAC8 (IC50s = 36 and 120 nM, respectively). It is selective for HDAC6 and -8 over HDAC1-5, -7, and -9 (IC50s = 12, 9, 23, >33, >33, 13, and >33 μM, respectively). BRD73954 (10 μM) increases acetylation of α-tubulin, a known HDAC6 substrate, but not histone H3, a substrate for HDAC1, -2, and -3, in HeLa cells.