BRL 50481
- $34 - $2691.1
- Product name: BRL 50481
- CAS: 433695-36-4
- MF: C9H12N2O4S
- MW: 244.27
- EINECS:1592732-453-0
- MDL Number:MFCD03039912
- Synonyms:5-NITRO-2,N,N-TRIMETHYLBENZENESULFONAMIDE;BRL 50481;N,N,2-TRIMETHYL-5-NITRO-BENZENESULFONAMIDE;3-(N,N-Dimethylsulfonamido)-4-methylnitrobenzene,5-Nitro-2-N,N-trimethylbenzenesulfonamide;Benzenesulfonamide, N,N,2-trimethyl-5-nitro-;-50481
42 prices
Selected condition:
Brand
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 10
- 5mg
- 10mg
- 25mg
- 50mg
- 50
- 100mg
- 200MG
- 250mg
- 500mg
- 1g
- ManufacturerAK Scientific
- Product number4516CJ
- Product descriptionN,N,2-Trimethyl-5-nitrobenzenesulfonamide
- Packaging100mg
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67146
- Product descriptionBRL-50481, 98%
- Packaging10mg
- Price$122
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0024926
- Product descriptionBRL 50481 95.00%
- Packaging100MG
- Price$1593.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6988
- Product descriptionBRL 50481
- Packaging5mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6988
- Product descriptionBRL 50481
- Packaging10mg
- Price$103
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6988
- Product descriptionBRL 50481
- Packaging25mg
- Price$205
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6988
- Product descriptionBRL 50481
- Packaging50mg
- Price$347
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6988
- Product descriptionBRL 50481
- Packaging100mg
- Price$567
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573365
- Product descriptionBRL 50481 >98%
- Packaging100mg
- Price$690.2
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573365
- Product descriptionBRL 50481 >98%
- Packaging250mg
- Price$1356.6
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb573365
- Product descriptionBRL 50481 >98%
- Packaging1g
- Price$2691.1
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19012
- Product descriptionBRL 50481
- Packaging25mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19012
- Product descriptionBRL 50481
- Packaging50mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19012
- Product descriptionBRL 50481
- Packaging100mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19012
- Product descriptionBRL 50481
- Packaging250mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFB19012
- Product descriptionBRL 50481
- Packaging500mg
- Price$275
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 4516CJ | N,N,2-Trimethyl-5-nitrobenzenesulfonamide | 100mg | $212 | 2021-12-16 | Buy |
Alfa Aesar | J67146 | BRL-50481, 98% | 10mg | $122 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0024926 | BRL 50481 95.00% | 100MG | $1593.9 | 2021-12-16 | Buy |
ApexBio Technology | B6988 | BRL 50481 | 5mg | $79 | 2021-12-16 | Buy |
ApexBio Technology | B6988 | BRL 50481 | 10mg | $103 | 2021-12-16 | Buy |
ApexBio Technology | B6988 | BRL 50481 | 25mg | $205 | 2021-12-16 | Buy |
ApexBio Technology | B6988 | BRL 50481 | 50mg | $347 | 2021-12-16 | Buy |
ApexBio Technology | B6988 | BRL 50481 | 100mg | $567 | 2021-12-16 | Buy |
Biorbyt Ltd | orb573365 | BRL 50481 >98% | 100mg | $690.2 | 2021-12-16 | Buy |
Biorbyt Ltd | orb573365 | BRL 50481 >98% | 250mg | $1356.6 | 2021-12-16 | Buy |
Biorbyt Ltd | orb573365 | BRL 50481 >98% | 1g | $2691.1 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB19012 | BRL 50481 | 25mg | $50 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB19012 | BRL 50481 | 50mg | $80 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB19012 | BRL 50481 | 100mg | $120 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB19012 | BRL 50481 | 250mg | $180 | 2021-12-16 | Buy |
Biosynth Carbosynth | FB19012 | BRL 50481 | 500mg | $275 | 2021-12-16 | Buy |
Properties
Melting point :65-67°C
Boiling point :391.1±52.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 12 mg/mL
form :solid
pka :-5?+-.0.70(Predicted)
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :391.1±52.0 °C(Predicted)
Density :1.334±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 12 mg/mL
form :solid
pka :-5?+-.0.70(Predicted)
color :white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Precautionary statements: |
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Description
BRL 50481 is a potent, selective inhibitor of phosphodiesterase (PDE) 7, inhibiting human recombinant PDE7A1 with a Ki value of 180 nM. It is much less effective against PDE3 and PDE4 and is without effect against PDE1B, PDE1C, PDE2, and PDE5. Through its effects on PDE7A1, BRL 50481 enhances the inhibitory effects of the PDE4 blocker rolipram on monocytes, lung macrophages, and CD8+ T-lymphocytes. BRL 50481, at 30 μM, promotes apoptosis in chronic lymphocytic leukemia cells overexpressing PDE7B, suggesting that this compound also acts against PDE7B. BRL 50481 can be used to evaluate the role of PDE7 isoforms in intracellular signaling.More related product prices
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Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
InvivoChem
Hefei TNJ Chemical Industry Co.,Ltd.
LEAP CHEM CO., LTD.
Hebei Weibang Biotechnology Co., Ltd
TargetMol Chemicals Inc.