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ChemicalBook >> CAS DataBase List >> CAY10574

CAY10574

CAY10574 price.
  • $25 - $997
  • Product name: CAY10574
  • CAS: 140651-18-9
  • MF: C9H10N6O
  • MW: 218.22
  • EINECS:
  • MDL Number:MFCD09262258
  • Synonyms:CAY10574;Cdk9 Inhibitor II;4-[2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]phenol;CAN-508;CAN-508 (CAN508);CaMKII Inhibitor, CK59 - CAS 140651-18-9 - Calbiochem;inhibit,CAN 508,ATP-competitive,Cyclin dependent kinase,esophageal,cells,CDK,CAN508,Inhibitor,adenocarcinoma,HT-29,CAN-508;Phenol, 4-[2-(3,5-diamino-1H-pyrazol-4-yl)diazenyl]-
12 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number1666AH
  • Product descriptionCDK9inhibitorII
  • Packaging1mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number1666AH
  • Product descriptionCDK9inhibitorII
  • Packaging50mg
  • Price$997
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011247
  • Product descriptionCAY10574 ≥95%
  • Packaging1mg
  • Price$25
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011247
  • Product descriptionCAY10574 ≥95%
  • Packaging5mg
  • Price$107
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011247
  • Product descriptionCAY10574 ≥95%
  • Packaging10mg
  • Price$186
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10011247
  • Product descriptionCAY10574 ≥95%
  • Packaging50mg
  • Price$807
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018885
  • Product descriptionCAN508
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018885
  • Product descriptionCAN508
  • Packaging10mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018885
  • Product descriptionCAN508
  • Packaging25mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0018885
  • Product descriptionCAN508
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number238811
  • Product descriptionCdk9 Inhibitor II - CAS 140651-18-9 - Calbiochem
  • Packaging5mg
  • Price$289
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC228128
  • Product descriptionCdk9InhibitorII
  • Packaging50mg
  • Price$605
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1666AH CDK9inhibitorII 1mg $125 2021-12-16 Buy
AK Scientific 1666AH CDK9inhibitorII 50mg $997 2021-12-16 Buy
Cayman Chemical 10011247 CAY10574 ≥95% 1mg $25 2024-03-01 Buy
Cayman Chemical 10011247 CAY10574 ≥95% 5mg $107 2024-03-01 Buy
Cayman Chemical 10011247 CAY10574 ≥95% 10mg $186 2024-03-01 Buy
Cayman Chemical 10011247 CAY10574 ≥95% 50mg $807 2024-03-01 Buy
ChemScene CS-0018885 CAN508 5mg $90 2021-12-16 Buy
ChemScene CS-0018885 CAN508 10mg $170 2021-12-16 Buy
ChemScene CS-0018885 CAN508 25mg $350 2021-12-16 Buy
ChemScene CS-0018885 CAN508 50mg $600 2021-12-16 Buy
Sigma-Aldrich 238811 Cdk9 Inhibitor II - CAS 140651-18-9 - Calbiochem 5mg $289 2024-03-01 Buy
TRC C228128 Cdk9InhibitorII 50mg $605 2021-12-16 Buy

Properties

Boiling point :638.3±55.0 °C(Predicted)
Density :1.67±0.1 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :DMF: 0.5 mg/ml; DMSO: 0.5 mg/ml
pka :8.52±0.30(Predicted)
form :Yellow semi-solid
color :Light yellow to yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Cdk9 Inhibitor II is an ATP-competitive inhibitor of cyclin-dependent kinase 9 (Cdk9; IC50 = 350 nM) and moderate inhibitor of similar enzymes including Cdk2-cyclin E. In the HT-29 cancer cell line, Cdk9 inhibitor II was observed to attenuate the frequency of the S-phase. Other Cdk9 Inhibitor II effects were shown to involve inhibition of mRNA synthesis, induction of p53, inhibition of IL-6 signaling and reduced phosphorylation of both retinoblastoma protein and RNA polymerase II at the C-terminal domain. Cdk9 Inhibitor II has been observed to be an effective antitumor and antimetastatic agent by disrupting TNFα signaling. Cdk9 Inhibitor II is an inhibitor of Cdk4, cyclin D1 and p70 S6 Kinase.